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NFKB1
| Symbol: | NFKB1 | | Name(s): | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | DKFZp686C01211, EBP-1, KBF1, MGC54151, NF-kappa-B, NFKB-p105, NFKB-p50 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17975552 |
the potential use of R-Roscovitine as a bitargeted anticancer drug that functions by simultaneously causing p53 activation and NF-kappaB suppression. |
| 18082293 |
Upregulation of NFkappaB pathway-related genes in DCs infected with the live RV vaccine strain results in protective activity of SPBNGAS-GAS. |
| 17242904 |
Unequal alterations in the levels of activated NF-kappaB subunits p50 and p65 might provide insights into the mechanisms of NF-kappaB action and anti-TNF-alpha therapy in AS. |
| 17950943 |
The reciprocal crosstalk between beta-catenin/Tcf pathway and NF-kappaB signaling in hMSCs is mediated through the regulation of lzts2 expression. |
| 18039660 |
Tyr-867 in Mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccharide-inducible NF-kappaB transcriptional activation |
| 18330586 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18347181 |
Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 18234964 |
TNF and possibly other inflammatory cytokines in the tumor-stroma matrix likely select for breast cancer cells that stably overexpress NF-kappaB, leading to greater cancer cell survival. |
| 18174252 |
the activation of NF-kappaB in human cancer cell lines and Min mice is inhibited by NO-donating aspirin |
| 17928629 |
The results of this study results support a role for NFkappaB in cytokine-induced prostaglandin E synthase expression in amnion mesenchymal cells in vitro. | →View more information from publications. |
Recent Publications on NFKB1: |  |
Diclofenac sodium inhibits NFkappaB transcription in osteoclasts.
A non-steroidal anti-inflammatory drug, diclofenac, acts efficiently... | 30th October, 2009
| Department of Pharmacology, Showa University School of Dentistry, 1-5-8
| J Dent Res. 2009 Nov;88(11):1042-7.
DOI Direct Link |
Oxaprozin-induced apoptosis on CD40 ligand-treated human primary monocytes is associated with the modulation of defined intracellular pathways.
The modulation of CD40L activity might represent a promising therapeutic... | 30th October, 2009
| Division of Cardiology, Faculty of Medicine, Foundation for Medical
| J Biomed Biotechnol. 2009;2009:478785. Epub 2009 Aug 10.
DOI Direct Link |
MicroRNA-9 inhibits ovarian cancer cell growth through regulation of NF-kappaB1.
MicroRNAs are emerging as important regulators of cancer-related... | 23rd October, 2009
| Tianjin Life Science Research Center and Basic Medical School, Tianjin
| FEBS J. 2009 Oct;276(19):5537-46. Epub 2009 Aug 21.
DOI Direct Link |
IkappaBalpha gene promoter polymorphisms are associated with hepatocarcinogenesis in patients infected with hepatitis B virus genotype C.
Genetic predisposition of nuclear factor kappaB signaling pathways linking... | 3rd October, 2009
| Department of Epidemiology.
| Carcinogenesis. 2009 Oct 1.
DOI Direct Link |
Computing Consistency Between Microarray Data andKnown Gene Regulation Relationships(submitted for IEEE Transactions on Information Technology in Biomedicine).
Microarray experiments produce expression patterns for thousands of genes... | 29th September, 2009
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| IEEE Trans Inf Technol Biomed. 2009 Sep 25.
DOI Direct Link |
→View more research publications. |
NFKB1 results (if any) from reagent suppliers | 
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