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NPPC
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17951249 |
Ostn is a naturally occurring ligand of the NPR-C clearance receptor and may act to locally modulate the actions of the natriuretic system in bone by blocking the clearance action of NPR-C, thus locally elevating levels of C-type natriuretic peptide. |
| 17709640 |
Aortic valve stenosis is characterized by distinct downregulation of the gene expression of C-type natriuretic peptide. |
| 15911070 |
discussion of C-type natriuretic peptide and guanylyl cyclase B receptor [review] |
| 12736257 |
human pro-CNP processing requires furin |
| 15231517 |
The first intron in the CNP sequence does not contain any additional enhancer-binding sites. However, the signal sequence is indispensable for secretion of CNP and its appropriate physiological function. |
| 14654233 |
Particulate guanylate cyclase activation by CNP induces a post-transductional down-regulation of soluble guanylate cyclase by a mechanism involving PKG and the proteasome pathway |
| 16179391 |
CNP is a modulator of acute inflammation in the blood vessel wall characterized by leukocyte and platelet activation, mediated, at least in part, via suppression of P-selectin expression. |
| 16109786 |
CNP is capable of autoregulating the expression of its cognate receptor. |
| 12167597 |
findings demonstrate that CNP metabolism is altered in patients with nephrotic syndrome and support the hypothesis that activation of renal CNP can be partially offset by a low-protein diet |
| 17289171 |
There is a discordant expression of NPPC in newborn infants of mothers with type 1 diabetes. | →View more information from publications. |
Recent Publications on NPPC: |  |
Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, alphaT3-1 and LbetaT2 gonadotroph cells.
In the pituitary, C-type natriuretic peptide (CNP) has been implicated as... | 12th August, 2009
| Endocrine Signalling Group, Veterinary Basic Sciences, Royal Veterinary
| J Endocrinol. 2009 Nov;203(2):215-29. Epub 2009 Aug 7.
DOI Direct Link |
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.
Northwestern Europeans are among the tallest of human populations. The... | 3rd July, 2009
| Department of Internal Medicine, Erasmus University Medical Center
| Hum Mol Genet. 2009 Sep 15;18(18):3516-24. Epub 2009 Jul 1.
DOI Direct Link |
C-type natriuretic peptide and overgrowth.
Natriuretic peptides are a family of structurally related peptides with... | 12th May, 2009
| Laboratory of Molecular Genetics, G. Gaslini Institute, Genova, Italy.
| Endocr Dev. 2009;14:61-6. Epub 2009 Feb 27.
DOI Direct Link |
Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting.
BACKGROUND: Ventricular dysfunction (VnD) after primary coronary artery... | 29th April, 2009
| Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and
| Anesthesiology. 2009 Apr;110(4):738-47.
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Safety of primary intraocular lens insertion in unilateral childhood traumatic cataract.
This study analyzes the results of cataract surgery with primary... | 15th April, 2009
| Department of Ophthalmology, Subharti Institute of Medical Sciences,
| JNMA J Nepal Med Assoc. 2008 Oct-Dec;47(172):179-85.
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→View more research publications. |
NPPC results (if any) from reagent suppliers | 
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CNP (C-19) Antibody sc-21372
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, NPPC, 4880, 2q37.1, NM_024409 ...
http://www.scbt.com/datasheet-21372-cnp-c-19-antibody.html...
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Search Results
PL-Nppc/GrsrJ JAX® Mice Database Site Section: JAX® Mice and services · jaxmice.jax.org/strain/004521.html - 30Kb ...
http://www.jax.org/search/Main.jsp?sg=0&qt=abnormalities&pag...
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CNP-53 (S-20) Antibody sc-21371
Spezies, Gen, Gen ID, Chromosomaler Locus, mRNA (Isoform) Accession #, Protein Accession #, OMIM™ Nummer. Human, NPPC, 4880, 2q37.1, NM_024409 · P23582 ...
http://www.scbt.com/de/datasheet-21371-cnp-53-s-20-antibody....
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CNP (H-115) Antibody sc-20952
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, NPPC, 4880, 2q37.1, NM_024409 · P23582
...
http://www.scbt.com/ja/datasheet-20952-cnp-h-115-antibody.ht...
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CNP (H-115) Antibody sc-20952
种属, 基因名称, 基因ID, 染色质位置, 亚型（mRNA）即位号码, 蛋白质即位号码, OMIM™ 号码. 人类, NPPC, 4880, 2q37.1, NM_024409 · P23582 ...
http://www.scbt.com/zh/datasheet-20952-cnp-h-115-antibody.ht...
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