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YBX1
| Symbol: | YBX1 | | Name(s): | Y box binding protein 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | BP-8, CSDA2, CSDB, DBPB, MDR-NF1, MGC104858, MGC110976, MGC117250, NSEP-1, NSEP1, YB-1, YB1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18075498 |
TGF-beta1 translation in proximal tubule cells requires YB-1 binding to a high-affinity site in the 5'-untranslated region of its mRNA. |
| 18172301 |
Both YB-1 and Twist expression could induce tumor progression, promoting cell growth and driving oncogenesis in various cancers. |
| 17822788 |
Y-box binding protein-1 (YB-1) as a new repressor of MMP-13 transactivation. |
| 17686777 |
YB-1 thus appears to have a novel regulatory role in NEIL2-mediated repair under oxidative stress. |
| 17595327 |
OSU-03012 prevents YBX1 from inducing EGFR. |
| 17459055 |
YB-1 nuclear expression is an important prognostic factor in ovarian carcinoma. |
| 17572683 |
PP2Cgamma modulates alternative splicing of specific pre-mRNAs coregulated by YB-1. |
| 15806160 |
activated Akt is positively correlated with the protein expression of the transcription/translation factor Y-box binding protein-1 (YB-1) in primary breast cancer; activated Akt binds to and phosphorylates the YB-1 cold shock domain at Ser102 |
| 12917425 |
YB1 interacts directly with Smad3 during TGFbeta signal inhibition by interferon gamma |
| 15735691 |
YB-1 overexpression can induce EGF independence in human mammary epithelial cells via activation of the EGFR pathway | →View more information from publications. |
Recent Publications on YBX1: |  |
Novel DNA mismatch-repair activity involving YB-1 in human mitochondria.
Maintenance of the mitochondrial genome (mtDNA) is essential for proper... | 7th August, 2009
| Laboratory of Molecular Gerontology, National Institute on
| DNA Repair (Amst). 2009 Jun 4;8(6):704-19. Epub 2009 Mar 9.
DOI Direct Link |
Translational activation of snail1 and other developmentally regulated transcription factors by YB-1 promotes an epithelial-mesenchymal transition.
Increased expression of the transcription/translation regulatory protein... | 4th August, 2009
| Department of Molecular Oncology, British Columbia Cancer Research Centre,
| Cancer Cell. 2009 May 5;15(5):402-15.
DOI Direct Link |
YB-1 translational control of epithelial-mesenchyme transition.
Transitions between epithelial and mesenchmal phenotypes play critical... | 4th August, 2009
| Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
| Cancer Cell. 2009 May 5;15(5):357-9.
DOI Direct Link |
[Studies of YB-1 protein in breast tumors]
The multifunctional mammalian protein YB-1 is involved in multiple DNA-... | 11th July, 2009
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| Klin Lab Diagn. 2009 Apr;(4):21-4.
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[YB-1 as a potential target in cancer therapy]
The 42-kDa multifunctional cellular protein Y-box protein 1 (YB-1) is... | 22nd May, 2009
| Institut fur Pathologie, Charite - Universitatsmedizin Berlin,
| Pathologe. 2008 Nov;29 Suppl 2:187-90.
DOI Direct Link |
→View more research publications. |
YBX1 results (if any) from reagent suppliers | 
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YBX1 Antibody (C-term)
293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the YBX1 gene (Lane 2) (Origene Technologies). ...
http://www.abgent.com/products/catalog_no/AP6295b_YBX1_Antib...
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YBX1 Antibody, RIP-grade | MBL International
The Y-box-binding protein (YBX1), family of cold shock proteins, is multifunctional and appears to regulate gene expression at both the
transcriptional and ...
http://www.mblintl.com/product/RN015P...
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NSEP1 antibody, NSEP1 Antibody, Rabbit Polyclonal Antibody
Synonym Names for NSEP1 antibody: NSEP1; BP-8, CSDB, DBPB, MDR-NF1, MGC110976, NSEP-1, YB-1, YB1, YBX1; Y-box-binding protein 1; Y-box transcription factor;
...
http://www.genwaybio.com/product_info.php?products_id=42521...
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RIP-Chip: RNA-Binding Protein Immunoprecipitation for Microarray ...
RN015P, YBX1 Antibody, RIP-grade. 200 µL. RN1001, RiboCluster Profiler™ RIP- Assay Kit, 10 assays. The RIP-Certified Antibodies have been validated for use
...
http://www.mblintl.com/rip-chip...
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Abgent - Translation and Regulation Antibodies ...
AT4545aNEW, WT1 monoclonal antibody (M01), ELISA,WB-Ce,WB-Re, H. AP6295a, YB1 ( YBX1) Antibody (N-term), WB, E, H. AP6295b, YBX1 Antibody (C-term), WB, E, H ...
http://www.abgent.com/products/category/nuclear_signaling/tr...
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YB-1 (A-16) Antibody sc-18057
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, YBX1, 4904, 1p34.2, NM_004559 ...
http://www.scbt.com/datasheet-18057-yb-1-a-16-antibody.html...
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STAU2 Antibody, RIP-grade | MBL International
RN015P Anti-YBX1 (polyclonal) RN1001 RIP-Assay Kit. Intended Use: For Research use only. Not for use in diagnostic procedure. ...
http://www.mblintl.com/product/RN013P...
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