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OAS1


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Gene DB Home
Symbol:OAS1
Name(s):2',5'-oligoadenylate synthetase 1, 40/46kDa
Type:protein-coding
Organism:Homo sapiens
Synonyms:IFI-4, OIAS, OIASI
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16824203 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17092260 Observational study of gene-disease association. (HuGE Navigator)
16644715 Observational study of gene-disease association. (HuGE Navigator)
12447867 Observational study of gene-environment interaction. (HuGE Navigator)
12944978 Observational study of gene-disease association. (HuGE Navigator)
15766558 Observational study of gene-disease association. (HuGE Navigator)
16014697 Observational study of gene-disease association. (HuGE Navigator)
15850793 IL-28A and IL-29 induced mRNA expression of the antiviral proteins 2',5'-OAS and MxA was abolished by overexpression of SOCS-1
15865429 Naturally mutated residues Lys404, Pro500 and Ser471 of E17 isozyme of 2',5'-oligoadenylate synthetase from a transgenic mouse serve an essential function in maintaining the enzyme activity of the protein.
11980899 role in interferon-gamma inhibition of respiratory syncytial virus infection of human epithelial cells

View more information from publications.

Recent Publications on OAS1:

Pubmed Logo
[Relationship between SNP rs10774671 on OAS-1 gene and spontaneous HBeAg seroconversion in chronic HBV infection]
OBJECTIVE: To investigate the relationship between the SNP rs10774671 on...
21st October, 2009
Department of Infectious Diseases, Third Affiliated Hospital of Sun Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2009 Feb;23(1):35-7.
Lack of association between the interferon-alpha signature and longitudinal changes in disease activity in systemic lupus erythematosus.
OBJECTIVE: To study the longitudinal expression of interferon...
6th October, 2009
Arthritis Centre of Excellence, Division of Genetics and Development, Ann Rheum Dis. 2009 Sep;68(9):1440-6. Epub 2008 Sep 4.
DOI Direct Link
2'-5'-Oligoadenylate synthetase is activated by a specific RNA sequence motif.
2'-5'-Oligoadenylate synthetase plays a central role in the cellular...
22nd September, 2009
Division of Molecular Radiation Biology, Department of Radiation Oncology, Biochem Biophys Res Commun. 2009 Oct 16;388(2):317-22. Epub 2009 Aug 5.
DOI Direct Link
Anti-hepatitis B virus activity and mechanisms of recombinant human serum albumin-interferon-alpha-2b fusion protein in vitro and in vivo.
AIMS: To evaluate the anti-hepatitis B virus (anti-HBV) effects and...
29th August, 2009
Institute of Clinical Pharmacology, Anhui Medical University, Hefei, PR Pharmacology. 2009;83(6):323-32. Epub 2009 Apr 29.
DOI Direct Link
Genetic variation in OAS1 is a risk factor for initial infection with West Nile virus in man.
West Nile virus (WNV) is a re-emerging pathogen that can cause fatal...
18th August, 2009
Molecular Signaling Section, Laboratory of Molecular Immunology, National PLoS Pathog. 2009 Feb;5(2):e1000321. Epub 2009 Feb 27.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Efficacy of Acetylcysteine in Patients Undergoing Surgery for Otosclerosis

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
7232678 Identification of oligoadenylate synthetase-like genes
7214787 Recombinant vaccine against botulinum neurotoxin
7074557 Ribosome display
7026121 Methods and compositions for diagnosing and monitoring transplant rejection

View more patents.

OAS1 results (if any) from reagent suppliers

Google CSE Logo
OAS1 (18-K) Antibody sc-100639
mouse monoclonal IgG2a, 100 µg/ml; raised against recombinant OAS1 of human origin ... OAS1 (18-K): sc-100639. Immunoperoxidase staining of formalin-fixed,
...
http://www.scbt.com/datasheet-100639-oas1-18-k-antibody.html...

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OAS1 Antibody (C-term)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected selected from the C-terminal region of human OAS1.
...
http://www.abgent.com/products/catalog_no/AP6226a...

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OAS1 antibody (ab86343) | Abcam
Rabbit polyclonal to OAS1. OAS1 is an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and
catalyzes the ...
http://www.abcam.com/OAS1-antibody-ab86343.html...

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OAS Antibody / OAS Antibodies
OAS1 (A-17) Antibody, sc-49833, goat IgG, C-terminus (h), WB, IF, ELISA, human ... OAS1 (V-18) Antibody, sc-49849, goat IgG, C-terminus (h), WB, IP, IF, ...
http://www.scbt.com/table-oas.html...

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Abgent Antibodies and Peptides
AM1008a, HA Tag Antibody, N/A. AP6226a, OAS1 Antibody (C-term), P00973 · AP7041b , PDK4 Antibody (C-term), Q16654 · AP1812b, Autophagy PAG5L Antibody (C-term ...
http://www.abgent.com/docs/abgent_newsletter_2007_jan...

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OAS1 (V-18) Antibody sc-49849
Western blot analysis of OAS1 expression in non-transfected: sc-110760 (A) and human OAS1 transfected (B) 293 whole cell lysates. 다운로드 ...
http://www.scbt.com/ko/datasheet-49849-oas1-v-18-antibody.ht...

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OAS1 antibody, 2 - Protein and Antibody Solutions Provider - GenWay
This product is temporary unavailable. Continue. Exact | Advanced Search. Specific Categories. Antibodies · Secondary Antibodies ...
http://www.genwaybio.com/product_info.php?products_id=366...

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