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OAS3


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Gene DB Home
Symbol:OAS3
Name(s):2'-5'-oligoadenylate synthetase 3, 100kDa
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC133260, p100
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12447867 Observational study of gene-environment interaction. (HuGE Navigator)
16014697 Observational study of gene-disease association. (HuGE Navigator)
17408844 OAS are interferon-inducible enzymes catalyzing 2'-5' instead of 3'-5' phosphodiester bond formation [review]

Recent Publications on OAS3:

Pubmed Logo
Activation of the 2-5OAS/RNase L pathway in CVB1 or HAV/18f infected FRhK-4 cells does not require induction of OAS1 or OAS2 expression.
The latent, constitutively expressed protein RNase L is activated in...
22nd May, 2009
Division of Molecular Biology, Office of Applied Research and Safety Virology. 2009 May 25;388(1):169-84. Epub 2009 Apr 19.
DOI Direct Link
The large form of human 2',5'-Oligoadenylate Synthetase (OAS3) exerts antiviral effect against Chikungunya virus.
Chikungunya virus (CHIKV) becomes one of the most important mosquito-borne...
24th February, 2009
Unite Interactions Moleculaires Flavivirus-Hotes and Centre National de Virology. 2009 Feb 5;384(1):216-22. Epub 2008 Dec 3.
DOI Direct Link
Increased expression of the type I interferon-inducible gene, lymphocyte antigen 6 complex locus E, in peripheral blood cells is predictive of lupus activity in a large cohort of Chinese lupus patients.
Several studies by microarray analysis and real-time polymerase chain...
30th January, 2009
Shanghai Clinical Centre of Rheumatic Diseases and Institute of Lupus. 2008 Sep;17(9):805-13.
DOI Direct Link
Cutaneous pharmacodynamics of a toll-like receptor 7 agonist, 852A, in humans.
852A is a specific toll-like receptor 7 (TLR7) agonist. Thirty-two healthy...
19th September, 2008
3M Pharmaceuticals, Department of Pharmacokinetics/Drug Metabolism, 3M J Clin Pharmacol. 2008 Jun;48(6):755-62. Epub 2008 Apr 9.
DOI Direct Link
Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation.
Studies were conducted to determine whether gene expression profiles...
24th May, 2007
Radiation Biology, Center for Cancer Research, National Cancer Cancer Res. 2007 Apr 15;67(8):3845-52.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Prediction of Response to Treatment of Patients With Chronic HCV Infection by Genetic Profile

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
7148326 Tumor antigen
7232678 Identification of oligoadenylate synthetase-like genes

View more patents.

OAS3 results (if any) from reagent suppliers

Google CSE Logo
OAS3 antibody - Carboxyterminal end (ab71780) | Abcam
Rabbit polyclonal to OAS3 - Carboxyterminal end. This protein is an enzyme included in the 2', 5' oligoadenylate synthase family.
http://www.abcam.com/OAS3-antibody-Carboxyterminal-end-ab717...

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OAS Antibody / OAS Antibodies
OAS3 (D-20) Antibody, sc-49867, goat IgG, N-terminus (m), WB, IF, ELISA, m, r. OAS3 (C-15) Antibody, sc-49866, goat IgG, C-terminus (h), WB, IF, ELISA ...
http://www.scbt.com/table-oas.html...

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OAS3 antibodies: Immunology > Innate Immunity > Cytokines ...
OAS3 antibodies. ... OAS3 antibody - Carboxyterminal end. WB, ELISA. Images. Rabbit polyclonal. Reacts with: Hu. Terms and conditions · Legal ...
http://www.abcam.com/index.html?t=248787&pt=1&c=531&ei=&mu=r...

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OAS3 (H-130) Antibody sc-99100
rabbit polyclonal IgG, 200µg/ml; epitope corresponding to amino acids 71-200 mapping near the N-terminus of OAS3 of human origin; recommended for detection
...
http://www.scbt.com/ko/datasheet-99100-oas3-h-130-antibody.h...

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Innate Immunity Antibodies :: Page 4
OAS1 Antibody, 48-425, H, E, IHC, ICC, 2'-5'-oligoadenylate Synthetase E16. OAS3 Antibody, 48-426, H, E, IHC, 2'-5'-oligoadenylate Synthetase 3 ...
http://www.prosci-inc.com/shop/catalog1/Innate-Immunity-Anti...

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OAS3 (M-190) Antibody sc-99101
rabbit polyclonal IgG, 200µg/ml; epitope corresponding to amino acids 1-190 mapping at the N-terminus of OAS3 of mouse origin; recommended for detection of
...
http://www.scbt.com/ko/datasheet-99101-oas3-m-190-antibody.h...

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Human OAS MAb (Clone 56/3)
OAS (69kDa), is one of three related proteins (along with OAS1 and OAS3) that catalyze the conversion of ATP into 2',5'-linked adenosine oligomers with the
...
http://www.rndsystems.com/pdf/mab1925.pdf...

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