Tuesday November 24 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

OGG1


Suggest Content
Advertise Here
Gene DB Home
Symbol:OGG1
Name(s):8-oxoguanine DNA glycosylase
Type:protein-coding
Organism:Homo sapiens
Synonyms:HMMH, HOGG1, MUTM, OGH1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18204928 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18270339 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
18272472 Observational study of gene-disease association. (HuGE Navigator)
18349297 Observational study of gene-disease association. (HuGE Navigator)
18272472 It is indicated that the hOGG1 codon 326 and XRCC1 codon 399 polymorphisms are risk factors of bladder cancer.
18222119 APEX1 serves to improve specificity of OGG1 for its biologically relevant substrates
11110971 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11307145 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11448535 Observational study of genotype prevalence, gene-disease association, and gene-environment interaction. (HuGE Navigator)
11675410 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRD8-oxoguanine DNA glycosylase isoform 2aProtein kinase C alpha--Pubmed

Recent Publications on OGG1:

Pubmed Logo
The hOGG1 Ser326Cys polymorphism and Huntington's disease.
Increasing evidence supports a role for oxidative DNA damage and impaired...
28th October, 2009
Department of Neuroscience, Neurological Clinic, University of Pisa, Via Toxicology. 2009 Oct 23.
DOI Direct Link
Do DNA repair genes OGG1, XRCC3 and XRCC7 have an impact on susceptibility to bladder cancer in the North Indian population?
OBJECTIVE: Polymorphisms in DNA repair genes may be associated with...
10th October, 2009
Department of Urology and Renal Transplantation, Sanjay Gandhi Post Mutat Res. 2009 Oct 6.
DOI Direct Link
Elevated ERCC1 gene expression in blood cells associated with exposure to arsenic from drinking water in Inner Mongolia.
BACKGROUND: Chronic arsenic exposure has been associated with human...
1st October, 2009
Center for Environmental Medicine, Asthma and Lung Biology, University of Anticancer Res. 2009 Aug;29(8):3253-9.
Deficiency of the oxidative damage-specific DNA glycosylase NEIL1 leads to reduced germinal center B cell expansion.
Mammalian cells possess multiple DNA glycosylases, including OGG1, NTH1,...
29th September, 2009
Laboratory for Immune Diversity, Research Center for Allergy and DNA Repair (Amst). 2009 Nov 2;8(11):1328-32. Epub 2009 Sep 24.
DOI Direct Link
Age-dependent down-regulation of mitochondrial 8-oxoguanine DNA glycosylase in SAM-P/8 mouse brain and its effect on brain aging.
Mitochondrial DNA (mtDNA) damage has been hypothesized to be responsible...
23rd September, 2009
Department of Biochemistry & Molecular Biology, Peking University Health Rejuvenation Res. 2009 Jun;12(3):209-15.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Study in PRE-Manifest Huntington's Disease of Coenzyme Q10 (UbiquinonE) Leading to Preventive Trials (PREQUEL)

Patents:

Patents logo
US Patent No.Title
7598031 Method for the detection of gene transcripts in blood and uses thereof
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
7109394 Methods for modulating floral organ identity, modulating floral organ number, increasing of meristem size, and delaying flowering time
7125658 Small protein that interacts with a ribonucleotide reductase subunit and uses thereof

View more patents.

OGG1 results (if any) from reagent suppliers

Google CSE Logo
Ogg1 antibody (ab204) | Abcam
Rabbit polyclonal to Ogg1. The Ogg1 gene encodes a DNA repair enzyme (N glycosylase/DNA lyase) that incises DNA at 8 oxoG residues. N glycosylase/DNA
lyase ...
http://www.abcam.com/Ogg1-antibody-ab204.html...

Thumbshot
OGG1/2 Antibody / OGG1/2 Antibodies
OGG1/2 Antibody / OGG1/2 Antibodies. ... OGG1/2 specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-ogg1-2.html...

Thumbshot
Ogg1 antibodies: Chromatin and Nuclear Signaling > DNA / RNA > DNA ...
Ogg1 antibodies. ... Ogg1 antibody (Biotin). IHC-P, WB, IHC-Fr. Rabbit polyclonal. Biotin conjugated. Reacts with: Hu, Rat, NHuPrm ...
http://www.abcam.com/index.html?t=9084&pt=1&c=876&ei=&mu=ra...

Thumbshot
OGG1/2 (N-20) Antibody sc-12074
OGG1/2 shRNA (h) Lentiviral Particles, sc-43983-V, 200 µl ... Western blot analysis of OGG1/2 expression in non-transfected 293T: sc-117752 (A), ...
http://www.scbt.com/datasheet-12074-ogg1-2-n-20-antibody.htm...

Thumbshot
OGG1 (8-oxoguanine DNA glycosylase 1) Antibody - Antibodies
Request » OGG1 (8-oxoguanine DNA glycosylase 1) Antibody. Name; E-Mail address; Country. Your Request. Locations. Germany · The Netherlands · North America ...
http://www.ibl-hamburg.com/products/antibodies/ogg1-8-oxogua...

Thumbshot
OGG1/2 siRNA (h) sc-43983
Click here for details. suitable control antibody: OGG1/2 (G-20): sc-12076; sqRT -PCR Primer also available: OGG1/2 (h)-PR: sc-43983-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-43983-ogg1-2-sirna-h.html...

Thumbshot
Ogg1 Assay Kit (CS0710) - Bulletin
to the slow AP-lyase reaction kinetics of Ogg1, the next .... provides radiolabeled substrate sufficient for 90 Ogg1 activity assays. ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Bulletin...

Thumbshot

Search Bioportfolio and other Life Science Sites for OGG1, or search for OGG1 on BioPortfolio's antibody search engine.
This page has been viewed 517 times
Recent Search Terms used to find this page:
OGG1 huntington s disease | ogg1 huntington | OGG1 huntington disease | Huntington s disease OGG1 | huntington s disease cure OGG1 | 8-oxoguanine huntington s disease | 8-oxoguanine DNA glycosylase antibody | ogg1 western | 8-oxoguanine glycosylase gene | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.