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ACO2


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Gene DB Home
Symbol:ACO2
Name(s):aconitase 2, mitochondrial
Type:protein-coding
Organism:Homo sapiens
Synonyms:ACONM, MGC20605, MGC33908
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12746427 ACO2 is often deleted in colorectal cancer but is unlikely to be the true target of the deletions
16625280 Manganese acts as an antagonist of iron, disrupting the enzymatic activity and gene expression of mACON and citrate metabolism in the prostate.
12198491 Lon protease selectively recognizes and degrades the oxidized, hydrophobic form of aconitase after mild oxidative modification, but that severe oxidation results in aconitase aggregation, which makes it a poor substrate for Lon.
16598741 The m-aconitase promoter is contained in a 153-bp 5' fragment lacking a TATA or CAAT sequence. Sp1 binding to specific Sp1 site is needed for promoter activity. Other transcription factors are recruited through protein-protein interactions.

Recent Publications on ACO2:

Pubmed Logo
Molecular characterization and association analysis of porcine PANE1 gene.
The proliferation associated nuclear element 1 (PANE1) is a novel gene...
28th August, 2009
Key Laboratory for Farm Animal Genetic Resources and Utilization of Mol Biol Rep. 2009 Aug 27.
DOI Direct Link
The effects of reduced end-tidal carbon dioxide tension on cerebral blood flow during heat stress.
Passive heat stress reduces arterial carbon dioxide partial pressure...
17th June, 2009
Texas Health Presbyterian Hospital Dallas, Institute for Exercise and J Physiol. 2009 Aug 1;587(Pt 15):3921-7. Epub 2009 Jun 15.
DOI Direct Link
Characterization of the 1-aminocyclopropane-1-carboxylic acid (ACC) oxidase multigene family of Malus domestica Borkh.
Two 1-aminocyclopropane-1-carboxylic acid (ACC) oxidase (ACO) genes have...
10th June, 2009
Institute of Molecular Biosciences, Massey University, Private Bag 11222, Phytochemistry. 2009 Feb;70(3):348-60. Epub 2009 Feb 14.
DOI Direct Link
Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2(+/-) mice: two-stage oxidative injury.
The determinants of susceptibility to troglitazone-induced idiosyncratic...
20th September, 2008
Department of Pharmacology, Yong Loo Lin School of Medicine, National Toxicol Appl Pharmacol. 2008 Aug 15;231(1):43-51. Epub 2008 Apr 12.
DOI Direct Link
Altered expression of 12S/MT-RNR1, MT-CO2/COX2, and MT-ATP6 mitochondrial genes in prostate cancer.
BACKGROUND: Prostate cancer is one of the commonest cancers worldwide and...
1st August, 2008
Centre de Genetica Medica i Molecular-IDIBELL, Hospital Duran i Reynals, Prostate. 2008 Jul 1;68(10):1086-96.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
5487642 Turbine nozzle positioning system
6174289 Cardiopulmonary exercise testing apparatus and method
6204437 DNA constructs and plants incorporating them
6261825 Production of amino acids using auxotrophic mutants of methylotrophic bacillus
6262346 Ripening-related DNAs from banana

View more patents.

ACO2 results (if any) from reagent suppliers

Google CSE Logo
HPA001097 Anti-ACO2 antibody produced in rabbit Prestige ...
HPA001097 Anti-ACO2 antibody produced in rabbit Prestige Antibodies Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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ACO2 Antibody (Center)
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with ACO2 antibody (Center) (Cat.#AP7561c), which was peroxidase-conjugated to ...
http://www.abgent.com/products/catalog_no/AP7561c_ACO2_Antib...

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ACO2 antibody - GeneTex Inc. - Your source for monoclonal ...
Product Description, Rabbit polyclonal antibody to ACO2 (aconitase 2, mitochondrial) ... Specificity, This antibody is specific to the Human ACO2
protein. ...
http://www.genetex.com/WebPage/Product/ProductDetail.aspx?Ca...

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ACO2 Antibody (C-term)
AP7561b).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ACO2 gene (Lane 2) (Origene Technologies). ...
http://www.abgent.com/products/catalog_no/AP7561b_ACO2_Antib...

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ACO2 (A-22) Antibody sc-130677
ACO2 (A-22): sc-130677. Immunoperoxidase staining of formalin-fixed, ... Western blot analysis of ACO2 expression in non-transfected (A) and human ACO2 ...
http://www.scbt.com/ko/datasheet-130677-aco2-a-22-antibody.h...

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Abgent - Cell and Function Antibodies
AP7561d, ACO2 Antibody (C-term), WB, IHC, E, H ... AP1936c, ACO2 Antibody ( Center), WB, E, H, M, R ... AP1936a, ACO2 Antibody (N-term), WB, E, H, R ...
http://www.abgent.com/products/category/cell_function...

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ACO2 siRNA (m) sc-61937
Click here for details. contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: ACO2 (m)-PR: sc-61937, 20 µl ...
http://www.scbt.com/ko/datasheet-61937-aco2-sirna-m.html...

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