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P2RX5


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Symbol:P2RX5
Name(s):purinergic receptor P2X, ligand-gated ion channel, 5
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC47755, P2X5, P2X5R
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12787128 Different purinergic receptors have different functional roles in human epidermis with P2Y1 and P2Y2 receptors controlling proliferation, while P2X5 and P2X7 receptors control early differentiation, terminal differentiation and death of keratinocytes.
16322791 a P2X5 frameshift mutation has a role in response to treatment of chronic myeloid leukemia
16967306 Increased keratinocyte P2X(5) receptor activity may, in part, be accountable for epidermal thinning in chronic venous insufficiency.
12880424 Non-melanoma skin cancers express functional purinergic receptors and that P2X7 receptor agonists significantly reduce cell numbers in vitro.
17001079 analysis of topology, helix-helix interactions, and oligomerization of P2X5 subunits

Recent Publications on P2RX5:

Pubmed Logo
New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC.
BACKGROUND: Expression of purine genes is modulated by inflammation or...
2nd September, 2009
Department of Bioinformatics, Ohio State University, Columbus, Ohio 43210, Inflamm Bowel Dis. 2009 Jul;15(7):971-84.
DOI Direct Link
Gene expression profiling of alpha-radiation-induced rat osteosarcomas: identification of dysregulated genes involved in radiation-induced tumorigenesis of bone.
To better understand the molecular basis of radiation-induced osteosarcoma...
23rd July, 2009
Laboratoire de Cancerologie Experimentale, iRCM, DSV, CEA, Int J Cancer. 2009 Aug 1;125(3):612-20.
DOI Direct Link
[Comparative mapping of mink (Mustela vison) chromosome 8p: localization of three human BAC clones]
Using fluorescent in situ hybridization (FISH), three human BAC clones,...
14th November, 2007
Genetika. 2007 Aug;43(8):1074-8.

Patents:

Patents logo
US Patent No.Title
7447594 Molecular cardiotoxicology modeling
6673908 Tumor necrosis factor receptor 2

P2RX5 results (if any) from reagent suppliers

Google CSE Logo
Antibodies to P2X Receptors
P9247, Anti-Purinergic Receptor P2X5 antibody produced in rabbit, (polyclonal), affinity isolated antibody, mouse ... P2rx5(94045) rat ... P2rx5(113995) ...
https://www.sigmaaldrich.com/etc/controller/controller-page....

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P1-PC
WH0005026M1, Monoclonal Anti-P2RX5 antibody produced in mouse, 1C5 (monoclonal), purified immunoglobulin, human ... P2RX5(5026) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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P2X5 (H-90) Antibody sc-25695
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, P2RX5, 5026, 17p13.3, NM_002561, ...
http://www.scbt.com/datasheet-25695-p2x5-h-90-antibody.html...

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P2X5 (N-16) Antibody sc-15191
Human, P2RX5, 5026, 17p13.3, NM_002561, NM_175080, NM_175081 · Q93086 · 602836. Mouse, P2rx5, 94045, 11 B4, NP_201578 ...
http://www.scbt.com/ko/datasheet-15191-p2x5-n-16-antibody.ht...

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P2X5 (V-19) Antibody sc-15192
ヒト, P2RX5, 5026, 17p13.3, NM_002561, NM_175080, NM_175081 · Q93086 · 602836. マウス, P2rx5, 94045, 11 B4, NP_201578 ...
http://www.scbt.com/ja/datasheet-15192-p2x5-v-19-antibody.ht...

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