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P2RY2
| Symbol: | P2RY2 | | Name(s): | purinergic receptor P2Y, G-protein coupled, 2 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | HP2U, MGC20088, MGC40010, P2RU1, P2U, P2U1, P2UR, P2Y2, P2Y2R | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16495779 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17137217 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17609252 |
Activation inhibits keratinocyte cell spreading and induces lamellipodium withdrawal. |
| 17599409 |
These results suggest that P2Y2R activation in salivary gland cells increases the EGFR-dependent expression of VCAM-1 and the binding of lymphocytes. |
| 17452627 |
Alpha v integrin complexes provide the P2Y2R with access to G alpha12 protein, thereby allowing activation of this heterotrimeric G protein that controls actin cytoskeletal rearrangements required for chemotaxis. |
| 17186500 |
P2Y(2) nucleotide receptors in U937 monocytic cells regulate the activation of extracellular signal-regulated kinases 1 and 2 (ERK 1/2) by inducing the clustering of alpha(v) integrins. |
| 12787128 |
Different purinergic receptors have different functional roles in human epidermis with P2Y1 and P2Y2 receptors controlling proliferation, while P2X5 and P2X7 receptors control early differentiation, terminal differentiation and death of keratinocytes. |
| 15778502 |
activation of the G protein-coupled P2Y2 receptor (P2Y2R) subtype expressed in human 1321N1 astrocytoma cells enhanced the release of sAPP alpha in a time- and dose-dependent manner |
| 14613890 |
Fibrinogen is required for nucleotide-induced primary granule release from human neutrophils through the P2Y2 receptor without a role for arachidonic acid metabolites. |
| 14645014 |
ADP-mediated P2Y1 and P2Y12 receptor activation supports LPA-induced platelet aggregation. | →View more information from publications. |
Recent Publications on P2RY2: |  |
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance.
Phagocytic removal of apoptotic cells occurs efficiently in vivo such that... | 7th October, 2009
| Beirne B. Carter Center for Immunology Research, University of Virginia,
| Nature. 2009 Sep 10;461(7261):282-6.
DOI Direct Link |
Association of the Purinergic Receptor P2Y, G-Protein Coupled, 2 (P2RY2) Gene With Myocardial Infarction in Japanese Men.
Background: Atherosclerosis leads to myocardial infarction (MI) and P2RY2... | 3rd October, 2009
| Division of Laboratory Medicine, Department of Pathology and Microbiology,
| Circ J. 2009 Oct 2.
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Purinergic receptor P2Y, G-protein coupled, 2 (P2RY2) gene is associated with cerebral infarction in Japanese subjects.
G-protein-coupled purinergic receptor P2Y2 (P2RY2) has an important role... | 19th September, 2009
| [1] Division of Laboratory Medicine, Department of Pathology and
| Hypertens Res. 2009 Sep 18.
DOI Direct Link |
The purinergic receptor P2Y, G-protein coupled, 2 (P2RY2) gene associated with essential hypertension in Japanese men.
P2RY2 has an important function in the regulation of blood pressure by... | 28th August, 2009
| [1] Division of Laboratory Medicine, Department of Pathology and
| J Hum Hypertens. 2009 Aug 27.
DOI Direct Link |
Effect of basolateral adenosine triphosphate on chloride secretion by bovine oviductal epithelium.
The composition of the fluid within the oviduct is largely determined by... | 30th August, 2008
| Department of Physiology, National University of Ireland Galway, Galway,
| Biol Reprod. 2008 Jun;78(6):1119-26. Epub 2008 Mar 5.
DOI Direct Link |
→View more research publications. |
P2RY2 results (if any) from reagent suppliers | 
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P2Y2 (A-20) Antibody sc-15209
Human, P2RY2, 5029, 11q13.4, NM_002564, NM_176071, NM_176072 · P41231 · 600041. Mouse, P2ry2, 18442, 7 E3, P35383, N/A. Ordering Information ...
http://www.scbt.com/datasheet-15209-p2y2-a-20-antibody.html...
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Antibodies to Neurotransmitter Receptors
P2ry2(29597), rat, IHC, WB, pricing. S0445, Anti-Serotonin 5-HT2B Receptor antibody produced in rabbit, (polyclonal), affinity isolated antibody ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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P2Y2 (C-20) Antibody sc-15210
Humain, P2RY2, 5029, 11q13.4, NM_002564, NM_176071, NM_176072 · P41231 · 600041. Souris, P2ry2, 18442, 7 E3, P35383, Non disponible ...
http://www.scbt.com/fr/datasheet-15210-p2y2-c-20-antibody.ht...
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BIOMOL International - Purinergic Receptor Antibodies
+, Ubiquitons and Zomes (Ubiquitin and Proteasome). +, Special Purpose Biochemicals. Purinergic Receptor Antibodies. Anti-P2Y1 (P2RY1) · Anti-P2Y2 (
P2RY2) ...
http://www.biomol.com/?pageId=36&categoryId=965...
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P2Y2 (A-20) Antibody sc-15209
种属, 基因名称, 基因ID, 染色质位置, 亚型（mRNA）即位号码, 蛋白质即位号码, OMIM™ 号码. 人类, P2RY2, 5029, 11q13.4, NM_002564, NM_176071, NM_176072 · P41231 ...
http://www.scbt.com/zh/datasheet-15209-p2y2-a-20-antibody.ht...
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SelectScreen® Cell-based GPCR Profiling Services
P2Y, P2RY2, NFAT-bla CHO-K1. P2Y, P2RY6, NFAT-bla CHO-K1. Platelet Activating Factor, PTAFR, U2OS. Prolactin Releasing Peptide, GPR10, NFAT-bla CHO-K1 ...
http://www.invitrogen.com/site/us/en/home/Products-and-Servi...
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P2Y2 (A-20) Antibody sc-15209
Human, P2RY2, 5029, 11q13.4, NM_002564, NM_176071, NM_176072 · P41231 · 600041. Mouse, P2ry2, 18442, 7 E3, P35383, 없음. 주문정보 ...
http://www.scbt.com/ko/datasheet-15209-p2y2-a-20-antibody.ht...
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