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P2RY6


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Symbol:P2RY6
Name(s):pyrimidinergic receptor P2Y, G-protein coupled, 6
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC15335, P2Y6
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17762175 on/off effect of IL-13 on P2Y(6)-induced Cl-secretion may help to identify the molecular determinants responsible for the CaCC channel activity
12623123 P2Y(6) receptors interact rapidly with the TNF alpha-related intracellular signals to prevent apoptotic cell death.
11690642 expression profile in human peripheral tissues and brain regions using PCR
16543499 inotropic effects of UDP, mediated by P2Y6 receptors
12691958 Adenine and uracil nucleotides differentially activate this receptor, which regulates the proliferation of lung cancer cells
16322472 P2Y receptors revealed that the P2Y6 (ligand of UDP) signaling pathway plays a predominant role in mediating human neutrophil peptides-induced IL-8 production.
12464620 hypertonic stress increases T cell interleukin-2 expression through a mechanism that involves ATP release, P2 receptor, and p38 MAPK activation
15796906 findings expand the pro-inflammatory biology of UDP mediated by the P2Y6 receptor
12716436 P2Y6 receptors highly responsive to UDP are endogenously expressed in human neuroblastoma SK-N-BE(2)C cells and they are involved in modulation of phospholipase C-coupled receptor-mediated Ca2+ mobilization by depleting the IP3-sensitive Ca2+ stores

Recent Publications on P2RY6:

Pubmed Logo
New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC.
BACKGROUND: Expression of purine genes is modulated by inflammation or...
2nd September, 2009
Department of Bioinformatics, Ohio State University, Columbus, Ohio 43210, Inflamm Bowel Dis. 2009 Jul;15(7):971-84.
DOI Direct Link
Gene expression profiling of alpha-radiation-induced rat osteosarcomas: identification of dysregulated genes involved in radiation-induced tumorigenesis of bone.
To better understand the molecular basis of radiation-induced osteosarcoma...
23rd July, 2009
Laboratoire de Cancerologie Experimentale, iRCM, DSV, CEA, Int J Cancer. 2009 Aug 1;125(3):612-20.
DOI Direct Link
Expression analysis of G Protein-Coupled Receptors in mouse macrophages.
ABSTRACT: BACKGROUND: Monocytes and macrophages express an extensive...
30th April, 2008
Cooperative Research Centre for Chronic Inflammatory Diseases and Special Immunome Res. 2008 Apr 29;4(1):5.
DOI Direct Link

Patents:

Patents logo
US Patent No.Title
7547687 Therapeutic treatment methods
7514209 Diagnosis and prognosis of breast cancer patients
7482334 Therapeutic treatment methods
7459437 Molecular determinants of myeloma bone disease and uses thereof
7426441 Methods for determining renal toxins

View more patents.

P2RY6 results (if any) from reagent suppliers

Google CSE Logo
P2Y6 (N-16) Antibody sc-15215
Human, P2RY6, 5031, 11q13.4, NM_004154, NM_176796, NM_176797, NM_176798 · Q15077 · 602451. Mouse, P2ry6, 233571, 7 E3, Q9ERK9 ...
http://www.scbt.com/datasheet-15215-p2y6-n-16-antibody.html...

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BIOMOL International - Purinergic Receptor Antibodies
Anti-P2Y6 (P2RY6) · Anti-P2Y12 (P2RY12) · Anti-P2Y13 (P2RY13, GPR86, GPR94) · Anti-P2Y14 (extracellular) (P2RY14, GPR105) ...
http://www.biomol.com/?pageId=36&categoryId=965...

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P2Y Antibody / P2Y Antibodies
PRODUCT NAME, CATALOG #, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. P2Y1 (A-15) Antibody, sc-15204, goat IgG, internal (h), WB, IF, ELISA, m, r, h, ...
http://www.scbt.com/table-p2y.html...

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SelectScreen® Cell-based GPCR Profiling Services
P2Y, P2RY6, NFAT-bla CHO-K1. Platelet Activating Factor, PTAFR, U2OS. Prolactin Releasing Peptide, GPR10, NFAT-bla CHO-K1. Prostanoid, GPR44 (CRTH2) ...
http://www.invitrogen.com/site/us/en/home/Products-and-Servi...

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P2Y Antibody / P2Y Antibodies
製品名, カタログ番号, アイソタイプ, エピトープ, アプリケーション, 動物種. P2Y1 ( A-15) 抗体, sc-15204, goat IgG, internal (h), WB, IF, ELISA, m, r, h, ...
http://www.scbt.com/ja/table-p2y.html...

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Cell-Based GPCR Reporter Assays
Pyrimidinergic), P2RY2, PDF Download · K1722 · K1337, X, Ca²+(Fluo-4). P2Y ( Purinergic), P2RY4, K1863, Ca²+(Fluo-4). P2Y (Purinergic), P2RY6, PDF Download
...
http://www.invitrogen.com/site/us/en/home/Products-and-Servi...

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P2Y6 (H-70) Antibody sc-20127
ヒト, P2RY6, 5031, 11q13.4, NM_004154, NM_176796, NM_176797, NM_176798 · Q15077 · 602451. マウス, P2ry6, 233571, 7 E3, Q9ERK9 ...
http://www.scbt.com/ja/datasheet-20127-p2y6-h-70-antibody.ht...

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