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P4HB
| Symbol: | P4HB | | Name(s): | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | DSI, ERBA2L, GIT, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15695804 |
Data show that protein disulfide isomerase can switch its conformation from dimer to tetramer in its functions as a foldase. |
| 15358778 |
domain c is required for the stabilization and maintenance of the chaperone function of PDI under extreme conditions |
| 15590633 |
data indicate that binding sites in three PDI domains, a, b', and a', contribute to efficient C-P4H tetramer assembly |
| 15611098 |
PDI can be S-nitrosated and PDI-SNO can be denitrosated by PDI suggesting that this enzyme could be intimately involved in the transport of intracellular NO equivalents to the cell surface. |
| 16847061 |
Protein disulfide isomerase (PDI) co-localizes with intracellular aggregates of mutant SOD1 (mSOD1) and binds to both wild type and mSOD1 in transgenic rat model of amyotrophic lateral sclerosis. |
Recent Publications on P4HB: |  |
Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers.
BACKGROUND: Although prior studies have demonstrated a smoking-induced... | 29th October, 2009
| The Pulmonary Center, Boston University Medical Center, Boston,
| PLoS One. 2009;4(4):e5043. Epub 2009 Apr 9.
DOI Direct Link |
An integrated approach for experimental target identification of hypoxia-induced miR-210.
miR-210 is a key player of cell response to hypoxia, modulating cell... | 15th October, 2009
| IRCCS-Policlinico San Donato, San Donato Milanese, Milan., Italy;
| J Biol Chem. 2009 Oct 13.
DOI Direct Link |
Proteomics of RAW 264.7 macrophages upon interaction with heat-inactivated Candida albicans cells unravel an anti-inflammatory response.
Murine macrophages (RAW 264.7) were allowed to interact with... | 10th September, 2009
| Departamento de Microbiologia II, Facultad de Farmacia, Universidad
| Proteomics. 2009 Jun;9(11):2995-3010.
DOI Direct Link |
Medical application of microbial biopolyesters polyhydroxyalkanoates.
Polyhydroxyalkanoates (PHA) are a family of polyesters synthesized by... | 16th June, 2009
| Department of Biological Sciences and Biotechnology, Protein Science
| Artif Cells Blood Substit Immobil Biotechnol. 2009;37(1):1-12. Epub 2009
DOI Direct Link |
Inhibition of transforming growth factor beta signaling by halofuginone as a modality for pancreas fibrosis prevention.
OBJECTIVES: Chronic pancreatitis is characterized by inflammation and... | 29th May, 2009
| Institute of Animal Sciences, The Volcani Center, Bet Dagan, Israel.
| Pancreas. 2009 May;38(4):427-35.
DOI Direct Link |
→View more research publications. |
P4HB results (if any) from reagent suppliers | 
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P4HB antibody (ab70415) | Abcam
Mouse polyclonal to P4HB. P4HB, Prolyl 4 hydroxylase subunit beta, is a multifunctional and highly abundant enzyme that belongs to the protein disulfide
...
http://www.abcam.com/P4HB-antibody-ab70415.html...
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ORDERING INFORMATION
P4HB (Prolyl 4-hydroxylase beta chain; also PDI) is a 60 kDa member of the ... Over aa 18 - 505, human P4HB shares 94% aa identity with mouse P4HB. ...
http://www.rndsystems.com/pdf/AF4236.pdf...
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Antibodies to ER and Golgi Proteins
affinity isolated antibody, rat ... P4hb(25506) human ... P4HB(5034) mouse ... P4hb(18453), human, rat, mouse, IF (i), IP, WB CL, pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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PDI (C-2) Antibody sc-74551
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, P4HB, 5034, 17q25.3, NM_000918 ...
http://www.scbt.com/datasheet-74551-pdi-c-2-antibody.html...
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P7122 Anti-Protein Disulfide Isomerase (DL-11) antibody produced ...
Gene Information, human ... P4HB(5034). rat ... P4hb(25506). mouse ... P4hb( 18453). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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Search for Products - R&D Systems
Protein Disulfide Isomerase/P4HB, Human P4HB Affinity Purified Polyclonal Ab, Goat IgG, IP, WB, AF4236, 100 µg, $355 ...
http://www.rndsystems.com/product_results.aspx?k=Collagen...
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P1-PC
AV48150, Anti-P4HB (AB1) antibody produced in rabbit, (polyclonal) ... HPA018884 , Anti-P4HB antibody produced in rabbit New, (polyclonal) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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