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FURIN
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17948127 |
Data suggest that furin levels in cystic fibrosis respiratory epithelial cells contributes to bacterial toxin-induced cell death, fibrosis, and local immunosuppression. |
| 17938254 |
s-HJV originates from a furin cleavage at position 332-335 |
| 18037384 |
These data support the hypothesis of a direct binding of heparin with site1 and site2, allowing selective exposure/accessibility of the REKR sequence, which is only then optimally cleaved by furin. |
| 17905608 |
HEPC MISSENSE MUTATION CAUSING INEFFICIENT CLEAVAGE INDICATES THAT THE FURIN BINDING SITE BE MORE THAN 4 RESIDUES |
| 17905609 |
the hepatic prohormone convertase furin mediates the posttranslational processing of hepcidin. The proteolytic cleavage of prohepcidin to hepcidin is not regulated by iron-transferrin or the HIF pathway |
| 17641413 |
Furin may constitute a marker for ovarian tumor progression and could contribute to predict the outcome of this disease. |
| 17909005 |
ppFurin expression in breast cancer cells decreased MMP-9 activity, but had no significant effect on TIMP-1 secretion. |
| 17477394 |
This study provides valuable insights into the structural properties of the furin prodomain in relation to its role in the folding of the furin zymogen and its inhibitory action toward furin. |
| 17360815 |
Furin P1A promoter undergoes transactivation via Sox9 binding during chondrogenesis. |
| 14644155 |
findings established the existence of a novel alternative/complementary pathway by which furin increases tumor cell invasion through an amplification/activation loop between MMP-2 and TGFbeta | →View more information from publications. |
Recent Publications on FURIN: |  |
Cell-surface processing of the metalloprotease pro-ADAMTS9 is influenced by the chaperone GRP94/GP96.
A Disintegrin-like And Metalloprotease domain with Thrombospondin type 1... | 31st October, 2009
| Cleveland Clinic, United States.
| J Biol Chem. 2009 Oct 29.
DOI Direct Link |
Role of L2 cysteines in papillomavirus infection and neutralization.
ABSTRACT: Vaccination of mice with minor capsid protein L2 or passive... | 29th October, 2009
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| Virol J. 2009 Oct 27;6(1):176.
DOI Direct Link |
Human testicular orphan receptor 4 enhances thyroid hormone receptor signaling.
The thyroid hormone receptor (TR) and human testicular orphan receptor 4... | 28th October, 2009
| Department of Biochemistry, School of Medicine, Chang-Gung University,
| J Cell Physiol. 2009 Oct 26.
DOI Direct Link |
Alternative mechanism of activation of the epithelial Na+ channel by cleavage.
We examined activation of the human epithelial sodium channel (ENaC) by... | 28th October, 2009
| Univ. Buffalo, United States;
| J Biol Chem. 2009 Oct 26.
DOI Direct Link |
The proprotein convertase furin in human trophoblast: Possible role in promoting trophoblast cell migration and invasion.
Furin, a proprotein convertase (PC), is ubiquitously expressed and... | 27th October, 2009
| State Key Laboratory of Reproductive Biology, Institute of Zoology,
| Placenta. 2009 Nov;30(11):929-38. Epub 2009 Oct 22.
DOI Direct Link |
→View more research publications. |
FURIN results (if any) from reagent suppliers | 
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