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PAEP
| Symbol: | PAEP | | Name(s): | progestagen-associated endometrial protein (placental protein 14, pregnancy-associated endometrial alpha-2-globulin, alpha uterine protein) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | GD, GdA, GdF, GdS, MGC138509, MGC142288, PAEG, PEP, PP14 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17570010 |
Prescence of glycodelin in peripheral white blood cells was demonstrated. |
| 17482165 |
Variability of seminal plasma glycodelin (Gd) adherence to spermatozoa suggests differences in sperm membrane properties according to the quality of the sperm; there is reduced Gd binding to normal-shaped male gametes compared with abnormal spermatozoa. |
| 17720699 |
glycodelin is a key regulatory protein of implantation and suggests that suberoylanilide hydroxamic acid may have a capacity to supplant steroid derivatives in the treatment of infertility. |
| 17716661 |
Removal of sialic acid residues from the active populations of GdA abrogates the activity of the molecule, suggesting that the extent of sialylation might be a factor regulating the activity of GdA. |
| 17649816 |
determination of Glycodelin A is not sensitive or specific enough for use as a tumour marker. |
| 17049713 |
Peri-implantation levels of glycodelin are lower in women with a history of recurrent miscarriage. |
| 17068141 |
Glycodelin positively regulates cell motility acting as mediator of histone deacetylase inhibitor-enhanced endometrial cell migration, suggesting involvement of glycodelin in dynamic endometrial gland morphogenesis during menstrual cycle. |
| 12672671 |
ZIF-1 is a differentially glycosylated isoform of glycodelin that potently inhibits human sperm-egg interaction. |
| 16269626 |
placental protein 14 promotes CD45 dimerization and clustering, a phenomenon that may regulate CD45 activity |
| 16759928 |
Down-regulation of PRB in the endometrium is concomitant with the presence of glycodelin in the endometrium, suggesting interaction. | →View more information from publications. |
Recent Publications on PAEP: |  |
Glycodelin A triggers T cell apoptosis through a novel calcium-independent galactose-binding lectin activity.
Glycodelin A (GdA) is one of the progesterone inducible endometrial... | 21st October, 2009
| Department of Biochemistry, Indian Institute of Science, Bangalore, India.
| Mol Immunol. 2009 Oct;46(16):3411-9. Epub 2009 Aug 14.
DOI Direct Link |
Ovarian cancer-derived glycodelin impairs in vitro dendritic cell maturation.
Local immunosuppressive mechanisms shape the tumor microenvironment and... | 9th October, 2009
| Department of Obstetrics and Gynecology, Ludwig-Maximilians University,
| J Immunother. 2009 Jun;32(5):492-7.
DOI Direct Link |
Functional characterization of the progestagen-associated endometrial protein gene in human melanoma.
Abstract Utilizing gene microarray profiling of melanoma samples, we have... | 6th October, 2009
| Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama,
| J Cell Mol Med. 2009 Oct 3.
DOI Direct Link |
The role of glycodelin in cell differentiation and tumor growth.
Glycodelin is a lipocalin family glycoprotein expressed mainly in... | 3rd September, 2009
| Department of Clinical Chemistry, Helsinki University Central Hospital and
| Scand J Clin Lab Invest. 2009;69(4):452-9.
DOI Direct Link |
Invasive hydatidiform mole: immunohistochemical labelling of inhibin/activin subunits, Ki67, p53 and glycodelin A in a rare case.
Invasive trophoblastic mole is an extremely rare condition. Its early... | 25th August, 2009
| Department of Obstetrics and Gynaecology, University of Rostock, Rostock,
| Acta Histochem. 2009;111(4):360-5. Epub 2009 Feb 4.
DOI Direct Link |
→View more research publications. |
PAEP results (if any) from reagent suppliers | 
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P1-PC
WH0005047M1, Monoclonal Anti-PAEP antibody produced in mouse, 6G2 (monoclonal), purified immunoglobulin, human ... PAEP(5047), human, ELISA (i), WB, pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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Placental Protein 14 / Glycodelin A antibody [EP870Y] (ab53289 ...
A synthetic peptide corresponding to residues near the C-terminal of human PAEP/ PEG. Reacts with (species key). Hu, Ms, Rat. Tested applications (see key) ...
http://www.abcam.com/Placental-Protein-14-Glycodelin-A-antib...
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Glycodelin (BTE 001) Antibody sc-57511
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, PAEP, 5047, 9q34.3, NM_001018049, ...
http://www.scbt.com/datasheet-57511-glycodelin-bte-001-antib...
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Glycodelin (BTE 001) Antibody sc-57511
... Numero de Accesion de Isoforma (ARNm), Numero de Accesion de la Proteina, Número de pedido: Humano, PAEP, 5047, 9q34.3, NM_001018049, NM_002571 · P09466
...
http://www.scbt.com/es/datasheet-57511-glycodelin-bte-001-an...
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Glycodelin (BTE 001) Antibody sc-57511
... Numéro d'accès d´isoforme d´ARNm, Numéro d'accès de la protéine, Numéro OMIM ™. Humain, PAEP, 5047, 9q34.3, NM_001018049, NM_002571 · P09466 ...
http://www.scbt.com/fr/datasheet-57511-glycodelin-bte-001-an...
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