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PAFAH2


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Symbol:PAFAH2
Name(s):platelet-activating factor acetylhydrolase 2, 40kDa
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLJ26025, HSD-PLA2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16650870 Observational study of gene-disease association. (HuGE Navigator)
17157859 Lp-PLA2 was higher in those with more extensive Coronary artery disease
12406338 presence of platelet-activating factor acetylhydrolase II in a restricted pattern in human skin; it is involved in protecting this organ against oxidative stress through the degradation of oxidatively modified bioactive phospholipids.
17272759 PAF-AH II exerts strong neuroprotective effects against ischemic injury: the neurological deficit scores, cerebral edema index, and relative infarction volume are all significantly lower in PAFAH2 transgenic mice than in wild-type mice.
11294621 examines substrate specificity for intracellular and plasma PAF-AHs

Recent Publications on PAFAH2:

Pubmed Logo
Pafah1b2 mutations suppress the development of hydrocephalus in compound Pafah1b1; Reln and Pafah1b1; Dab1 mutant mice.
Reelin, an extracellular protein that signals through the Dab1 adapter...
25th September, 2008
The Cain Foundation Laboratories, Texas Children's Hospital, Houston, TX Neurosci Lett. 2008 Jul 4;439(1):100-5. Epub 2008 May 2.
DOI Direct Link
Protection against oxidative stress-induced hepatic injury by intracellular type II platelet-activating factor acetylhydrolase by metabolism of oxidized phospholipids in vivo.
Membrane phospholipids are susceptible to oxidation, which is involved in...
15th February, 2008
Graduate School of Pharmaceutical Science, University of Tokyo, 7-3-1 J Biol Chem. 2008 Jan 18;283(3):1628-36. Epub 2007 Nov 17.
DOI Direct Link

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
7598031 Method for the detection of gene transcripts in blood and uses thereof
7547687 Therapeutic treatment methods
7482334 Therapeutic treatment methods
6673908 Tumor necrosis factor receptor 2

View more patents.

PAFAH2 results (if any) from reagent suppliers

Google CSE Logo
P1-PC
HPA018157, Anti-PAFAH2 antibody produced in rabbit, (polyclonal), affinity isolated antibody, human ... PAFAH2(5051), human, IHC (p), PA, pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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PAF Acetylhydrolase Antibody / PAF Acetylhydrolase Antibodies
PAF Acetylhydrolase Antibody / PAF Acetylhydrolase Antibodies.
http://www.scbt.com/ko/table-paf_acetylhydrolase.html...

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Abcam antibodies and reagents product map
... PAFAH1B2 proteins and peptides (1) · PAFAH1B3 antibodies (1) · PAFAH2 antibodies (1) · PANK3 antibodies (2) · PAP2D antibodies (1) · PBR antibodies (2
) ...
http://www.abcam.com/index.html?cl=2105&pageconfig=productma...

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PAF acetylhydrolase 2 siRNA (h) sc-88153
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, PAFAH2, 5051, 1p36.11, NM_000437 ...
http://www.scbt.com/ko/datasheet-88153-paf-acetylhydrolase-2...

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Abcam antibodies and reagents product map
... MTMR14 antibodies (1) · MTMR8 antibodies (1) · MTMR9 antibodies (1) · MTMR9 proteins and peptides (1) · PAFAH2 antibodies (1) · PIB5PA antibodies (1) ...
http://www.abcam.com/index.html?c=2105...

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PAF acetylhydrolase 2 siRNA (h) sc-88153
... Numero de Accesion de Isoforma (ARNm), Numero de Accesion de la Proteina, Número de pedido: Humano, PAFAH2, 5051, 1p36.11, NM_000437 · Q99487 ...
http://www.scbt.com/es/datasheet-88153-paf-acetylhydrolase-2...

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PAF acetylhydrolase 2 siRNA (m) sc-151991
... Numero de Accesion de Isoforma (ARNm), Numero de Accesion de la Proteina, Número de pedido: Ratón, Pafah2, 100163, 4 D3, Q8VDG7, No Aplicable ...
http://www.scbt.com/es/datasheet-151991-paf-acetylhydrolase-...

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