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PAPPA
| Symbol: | PAPPA | | Name(s): | pregnancy-associated plasma protein A, pappalysin 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18089325 |
PAPP-A level is elevated in renal transplant patients and high levels of PAPP-A may be a prognostic marker associated with high serum levels of urea, creatinine, uric acid, and C-reactive protein. |
| 17509577 |
Maternal serum PAPP-A levels in the late first trimester of pregnancy are associated with subsequent fetal growth,both physiologic variation and abnormal growth. |
| 17700210 |
PAPP-A IVS6+95 C allele is an independent risk factor for acute myocardial infarction even after adjustment for traditional risk factors. |
| 17437322 |
Maternal systemic lupus erythematosus does not affect first trimester level. |
| 15647258 |
the proform of eosinophil major basic protein inhibits the proteolytic activity of PAPP-A |
| 16963045 |
Preliminary evidence suggests that first-trimester uterine artery Doppler measurements do not correlate with maternal serum levels of free beta-hCG and PAPP-A. |
| 17145752 |
PAPP-A requires the formation of intermolecular proteinase-inhibitor disulfide bonds and glycosaminoglycan covalently bound to the inhibitor |
| 11897673 |
phorbol ester tumor promoters and simian virus 40 transformation regulate IGFBP-4 proteolysis in human fibroblasts through induction of a novel inhibitor of PAPP-A, pro-MBP |
| 12524241 |
Elevated serum PAPP-A levels represent a potential marker of the degree of echogenicity of carotid atherosclerotic plaques in asymptomatic hyperlipidemic patients at high cardiovascular risk. |
| 15262980 |
PAPPA Lin12-notch repeats bind calcium and determine its proteolytic specificity | →View more information from publications. |
Recent Publications on PAPPA: |  |
Human microRNA target analysis and gene ontology clustering by GOmir, a novel stand-alone application.
BACKGROUND: microRNAs (miRNAs) are single-stranded RNA molecules of about... | 3rd November, 2009
| Cell & Gene Therapy Laboratory, Biomedical Research Foundation of the
| BMC Bioinformatics. 2009 Jun 16;10 Suppl 6:S20.
DOI Direct Link |
Steady-state amprenavir and tenofovir pharmacokinetics after coadministration of unboosted or ritonavir-boosted fosamprenavir with tenofovir disoproxil fumarate in healthy volunteers.
Objective An open-label, three-period pharmacokinetic study was conducted... | 30th October, 2009
| Private Practice, Voorhees, NJ, USA.
| HIV Med. 2009 Oct 23.
DOI Direct Link |
Application of multivariate statistical methods for groundwater physicochemical and biological quality assessment in the context of public health.
Three representative areas (lowland, semi-mountainous, and coastal) have... | 28th October, 2009
| Clinical Chemistry - Biochemistry Section, Department of Medical
| Environ Monit Assess. 2009 Oct 27.
DOI Direct Link |
Cell cycle and apoptosis regulatory gene expression in the bone marrow of patients with de novo myelodysplastic syndromes (MDS).
Deregulation of cell cycle and apoptosis pathways are known contributors... | 9th October, 2009
| Attikon University Hospital, 2nd Propedeutic Clinic of Internal Medicine,
| Ann Hematol. 2009 Oct 8.
DOI Direct Link |
Acute lymphoplasmacytoid dendritic cell (DC2) leukemia: Results from the Hellenic Dendritic Cell Leukemia Study Group.
We present a cohort of 22 patients with type 2 dendritic cell (DC2) acute... | 2nd October, 2009
| Flow Cytometry Laboratory, Department of Immunology, Athens Regional
| Leuk Res. 2009 Sep 28.
DOI Direct Link |
→View more research publications. |
PAPPA results (if any) from reagent suppliers | 
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PAPPA protein, PAPP-A Fragment: Human, Recombinant, E Coli ...
Buy quality PAPPA protein (e coli), PAPPA, PAPP-A Fragment: Human, Recombinant, E Coli recombinant protein, (sds-page n/a).
http://www.genwaybio.com/product_info.php?products_id=288126...
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PAPP A antibody [10A5] (ab10193) | Abcam
sELISA: Can be used in immunoassay for the detection of human PAPPA antigen as an antibody pair with Mouse monoclonal [3C8] to PAPPA (ab10194) for coating. ...
http://www.abcam.com/PAPP-A-antibody-10A5-ab10193.html...
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PAPPA native protein, PAPP-A native protein
Buy quality PAPPA native protein (retroplacental blood), PAPPA, PAPP-A native protein, (elisa n/a). PAPP-A; EC 3.4.24.79; Pregnancy-associated plasma ...
http://www.genwaybio.com/product_info.php?products_id=248609...
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Aldh3A1 Antibody Aldehyde dehydrogenase family3 member A1
Vasiliou V and Pappa A. Polymorphisms of human aldehyde dehydrogenases. ... Pappa A, Sophos NA and Vasiliou V. Corneal and Stomach expression of aldehyde
...
http://www.prosci-inc.com/shop/catalog1/Aldh3A1-Antibody-p-6...
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PRG2 antibody [BMK-13] (ab48372) | Abcam
The proform acts as a proteinase inhibitor, reducing the activity of PAPPA. In pregnancy serum, the proform exists as a disulfide-linked 2:2 heterotetramer ...
http://www.abcam.com/PRG2-antibody-BMK-13-ab48372.html...
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PAPP-A (D-15) Antibody sc-47301
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, PAPPA, 5069, 9q33.1, NM_002581 ...
http://www.scbt.com/datasheet-47301-papp-a-d-15-antibody.htm...
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P1-PC
WH0005069M1, Monoclonal Anti-PAPPA antibody produced in mouse, 1G3 (monoclonal), purified immunoglobulin, human ... PAPPA(5069) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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