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FOXP3


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Gene DB Home
Symbol:FOXP3
Name(s):forkhead box P3
Type:protein-coding
Organism:Homo sapiens
Synonyms:AIID, DIETER, IPEX, JM2, MGC141961, MGC141963, PIDX, XPID
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18261176 Campath-1H (Alemtuzumab) is an effective immunodepletion agent used in renal transplantation which increass FOXP3 regulatory T cells.
18092263 There is an accumulation of FoxP3-expressing regulatory T cells in RA SF, and such recruitment may be dependent on the distinct chemokine receptors expressed on regulatory T cells.
18178814 TNreg cells are precursors for human Treg cells; these cells require a high level of FoxP3 expression to maintain their suppressive function.
17851585 proportions of FOXP3-bearing lymphocytes were higher in vertical than in radial growth phase, as well as in late than in early melanoma stages
12750858 Observational study of gene-disease association. (HuGE Navigator)
15220219 Observational study of gene-disease association. (HuGE Navigator)
16901927 Observational study of gene-disease association. (HuGE Navigator)
16996248 Observational study of gene-disease association. (HuGE Navigator)
17418529 Observational study of gene-disease association. (HuGE Navigator)
17526924 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

BioNews Results for FOXP3

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Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4+CD25+ regulatory T cells of T1D subjects
MDLinx:  Nov 13 2009 11:04AM Matching: foxp3
Atopic Dermatitis Therapy: Studies from C. Brandt and colleagues yield new information about atopic dermatitis therapy
NewsRX:  Nov 7 2009 5:41AM Matching: foxp3
Homeostasis of peripheral FoxP3+ CD4+ regulatory T cells in patients with early and late stage breast cancer
MDLinx:  Oct 30 2009 10:18AM Matching: foxp3
Regular Tai Chi Chuan exercise improves T cell helper function of patients with type 2 diabetes mellitus with an increase in T-bet transcription factor and IL-12 production
British Journal of Sports Medicine:  Oct 28 2009 10:46PM Matching: foxp3
The effects of adalimumab and methotrexate treatment on peripheral Th17 cells and IL-17/IL-6 secretion in rheumatoid arthritis patients
MDLinx:  Oct 28 2009 10:35AM Matching: foxp3
Promote your company here: BioNewsCast - Press Release Distribution

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Clinical Trials:

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Role of Regulatory T Cells in Pathogenesis of Primary IgA Nephropathy

Patents:

Patents logo
US Patent No.Title
7608683 Stress proteins and peptides and methods of use thereof
7371385 Method of treating immune pathologies with low dose estrogen
7439042 Yeast-based therapeutic for chronic hepatitis C infection
7507542 Method for regulating immune function using the FOXP3 protein
7527972 Uses of bispecific antibody coated dendritic cells pulsed with antigens and GM-CSF in immune regulation

View more patents.

FOXP3 results (if any) from reagent suppliers

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FOXP3 antibody (ab10563) | Abcam
The antibody has not been tested in WB against endogenous FOXP3. .... See below for FOXP3 antibody images, references, products related to ab10563 and other ...
http://www.abcam.com/foxp3-antibody-ab10563.html...

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Regulatory T Cells: Foxp3, GITR, CD127
In the human, two isoforms can be present; the anti-mouse/rat Foxp3 antibody, FJK-16s, crossreacts to human Foxp3 but recognizes the region that can be ...
http://www.ebioscience.com/ebioscience/whatsnew/TregPage/Tre...

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The Abcam catalog
FOXP3 antibodies. ... FOXP3 antibody - ChIP Grade. IHC-P, ICC, WB, IHC-Fr, ChIP ... FOXP3 antibody [mAbcam 22510]. Flow Cyt, IHC-P, WB, IHC-Fr ...
http://www.abcam.com/index.html?t=36858&pt=1&c=3415...

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eBioscience - Foxp3 Antibodies for Flow Cytometry, IHC & WB
The shift/increase in background staining is not seen in other publications nor in any eBioscience data comparing PCH101 to any other Foxp3 antibody. ...
http://www.ebioscience.com/ebioscience/whatsnew/Foxp3/Foxp3....

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PE Anti-human FOXP3 Antibody - BioLegend
PE Anti-human FOXP3 Antibody - FOXP3 is a 50-55 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX.
http://www.biolegend.com/pe-anti-human-foxp3-2906.html...

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FOXP3 (2A11G9) Antibody sc-53876
Western blot analysis of FOXP3 expression in mouse brain tissue extract. sc- 53876. FOXP3 (2A11G9): sc-53876. Immunofluorescence staining of methanol-fixed
...
http://www.scbt.com/datasheet-53876-foxp3-2a11g9-antibody.ht...

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Pacific Blue Anti-mouse FOXP3 Antibody - BioLegend
Pacific Blue Anti-mouse FOXP3 Antibody - FOXP3 is a transcription factor of 50 kd.
http://www.biolegend.com/pacific-blue-anti-mouse-foxp3-antib...

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