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PDGFB
| Symbol: | PDGFB | | Name(s): | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | FLJ12858, PDGF2, SIS, SSV, c-sis | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17998143 |
ERK5 modulates platelet-derived growth factor-dependent biologic activities in human hepatic stellate cells |
| 17338425 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17944929 |
Increased expression of PDGF/Ralphabeta may play an important role in the mechanism of growth of...paediatric fibromatous lesions |
| 17950782 |
we found COL1A1-PDGFB rearrangements appear more prevalent in Dermatofibrosarcoma protuberans (DFSP) than previously reported. |
| 17724602 |
The trichloroacetic acid-treated epidermis acts as a major source of growth factors, including PDGF-B, before undergoing full necrosis. |
| 17958740 |
thrombin may play an important role in the proliferation of A172 cells by inducing PDGF-AB secretion and that thrombin's action is mediated by its proteolytic activity |
| 17671690 |
endothelial and lung cancer cells seem to interact via various paracrine pathways, e.g. by the reciprocal induction of VEGF and PDGF-BB |
| 17157157 |
The mRNA levels of PDGFB were significantly produced by the megakaryocytes may be associated with the etiology of bone marrow fibrosis in AMM. |
| 17608589 |
Er:YAG laser used alone or in combination with rhPDGF-BB application may offer a promising periodontal therapy for conditioning root surfaces, although the combined application seemed to be slightly more effective. |
| 17395886 |
In absence of serum, it required a combination of Ang-2 and PDGF-BB to increase invasion. The heightened invasion was dependent on serine proteases and MMPs, combination of Ang-2 and PDGF-BB increased urokinase plasminogen-activator receptor expression. | →View more information from publications. |
Recent Publications on PDGFB: |  |
Spinal glioma: platelet-derived growth factor B-mediated oncogenesis in the spinal cord.
Human platelet-derived growth factor B (hPDGFB) has been characterized in... | 17th October, 2008
| Departments of Pediatrics and Genetics, Norris Cotton Cancer Center,
| Cancer Res. 2008 Oct 15;68(20):8507-15.
DOI Direct Link |
[Genetics of osteoporosis]
Osteoporosis is a common disease with a strong genetic componenet... | 17th October, 2008
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| Vestn Ross Akad Med Nauk. 2008;(6):37-41.
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Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression.
A coordinated reciprocal interaction between epithelium and mesenchyme is... | 7th October, 2008
| Division of Oral Health, Growth and Development, Faculty of Dental
| J Biol Chem. 2008 Aug 22;283(34):23139-49. Epub 2008 Jun 17.
DOI Direct Link |
Complex t(5;8) involving the CSPG2 and PTK2B genes in a case of dermatofibrosarcoma protuberans without the COL1A1-PDGFB fusion.
Dermatofibrosarcoma protuberans (DFSP) is a rare, dermal neoplasm of... | 19th September, 2008
| Laboratoire de Genetique des Tumeurs Solides, Faculte de Medecine, Centre
| Virchows Arch. 2008 Jun;452(6):689-96. Epub 2008 Feb 6.
DOI Direct Link |
Mechanisms of angiogenesis.
Tissue activity of angiogenesis depends on the balance of many stimulating... | 9th September, 2008
| Institute of Carcinogenesis, Blokhin Cancer Research Center, Russian
| Biochemistry (Mosc). 2008 Jul;73(7):751-62.
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→View more research publications. |
PDGFB results (if any) from reagent suppliers | 
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HPA011972 Anti PDGFB antibody produced in rabbit Prestige ...
HPA011972 Anti-PDGFB antibody produced in rabbit Prestige Antibodies™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol ...
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...
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PDGFB Antibody (C-term)
"PDGFB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and
...
http://www.abgent.com/products/catalog_no/AP1721a/techsuppor...
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PDGFB platelet-derived growth factor beta polypeptide (simian ...
PDGFB; C-SIS; FLJ12858; PDGF2; SIS; SSV. Refseq ID(s) ... HPA011972, Anti-PDGFB antibody produced in rabbit Prestige Antibodies™ Powered by Atlas Antibodies ...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...
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Orbigen Inc. - Orbigen Inc.
Platelet-derived growth factor B (PDGFB) polyclonal antibody ... Platelet- derived growth factor beta (PDGFB) is a member of the platelet-derived growth
...
http://www.orbigen.com/commerce/catalog/product.jsp?product_...
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Antibodies to Platelet Growth Factor (PDGF)
PDGFB(5155), human, ELISA (i), Neutral, WB. P2110, Anti-Platelet-Derived Growth Factor Receptor α antibody produced in goat, affinity isolated antibody ...
http://www.sigmaaldrich.com/catalog/search/TablePage/1383592...
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Protein and Antibody Solutions Provider - GenWay
PDGF BB; Becaplermin C sis Oncogene SIS PDG B chain PDGB PDGF2 PDGFB/COL1A1 fusion gene Platelet derived growth factor B chain Platelet d ...
https://www.genwaybio.com/advanced_search_result.php?so=c&ex...
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P1 to PN
HPA011972, Anti-PDGFB antibody produced in rabbit New, affinity isolated antibody, human ... PDGFB(5155), human, IHC (p), PA ...
http://www.sigmaaldrich.com/catalog/search/TablePage/1457467...
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Purified Anti-MMP9 Antibody - BioLegend
Interaction: MMP2, MMP9, Fibronectin 1, Nidogen 1, Integrin a5, Integrin a2, Matrilin 2, Bone morphogenic protein 1, PDGFb, FGF7, CD44, CD36, Collagen, ...
http://www.biolegend.com/purified-anti-mmp9-antibody-4370.ht...
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Cytokines, Chemokines, Growth Factors
Platelet-derived growth factor B (PDGFB) polyclonal antibody, PAB-10941, $175.00 . Platelet-derived growth factor C (PDGFC) polyclonal antibody, PAB-10942 ...
http://www.orbigen.com/dictionary/cat1050.htm...
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PDAP1 antibody (ab36842) datasheet | Abcam
Chicken polyclonal to PDAP1. PDAP1 enhances PDGFA stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB (By similarity). ...
http://www.abcam.com/index.html?datasheet=36842...
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