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ZAK
| Symbol: | ZAK | | Name(s): | sterile alpha motif and leucine zipper containing kinase AZK | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | AZK, MLK7, MLT, MLTK, MRK, mlklak | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15485649 |
ZAK induces characteristic hypertrophic growth features, including increased cell size, elevated atrial natriuretic factor expression, and increased actin fiber organization |
| 12535642 |
Results suggest that ZAK might play a role as an upstream signal to suppress the ZZaPK function and decrease E2F expression. |
| 15342622 |
Data show that in response to radiation, MRK controls two independent pathways: the Chk2-Cdc25A pathway leading to cell cycle arrest and the p38gamma MAPK pathway |
| 15465036 |
Results suggest that a ZAK mediates TGF-beta-induced cardiac hypertrophic growth via a novel TGF-beta signaling pathway. |
| 15737997 |
Mixed lineage kinase 7 (MLK7), a splice variant of the ZAK gene, encodes an isoform which is the MAPKKK required for modulation of the stress-activated MAPKs downstream of anisomycin and UV stimulation. |
ZAK results (if any) from reagent suppliers | 
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FAS (X-20) Antibody sc-1024
Zak, S. et al. 2008. Lack of thrombospondin-1 increases angiogenesis in a model of chronic inflammatory bowel disease. Int J Colorectal Dis. 23: 297-304. ...
http://www.scbt.com/datasheet-1024-fas-x-20-antibody.html...
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3C-3E
Monoclonal Anti-ZAK antibody produced in mouse clone 3D11, purified immunoglobulin, buffered aqueous solution, 3D11 (monoclonal) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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uPA (H-140) Antibody sc-14019
ZAK induces MMP-2 activity via JNK/p38 signals and reduces MMP-9 activity by increasing TIMP-1/2 expression in H9c2 cardiomyoblast cells. Mol. Cell. ...
http://www.scbt.com/datasheet-14019-upa-h-140-antibody.html...
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Panorama® Antibody Array - Kinase Protein
ZAK. sterile alpha motif and leucine zipper containing kinase AZK. 51776 · ZAP70 . zeta-chain (TCR) associated protein kinase 70 kDa ...
http://www.sigmaaldrich.com/life-science/cell-biology/protei...
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MLTK (D-18) Antibody sc-67682
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ZAK, 51776, 2q31.1, Q9NYL2 ...
http://www.scbt.com/datasheet-67682-mltk-d-18-antibody.html...
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SelectScreen® Biochemical Kinase Profiling Service LanthaScreen ...
2 Jul 2009 ... ZAK. 5. Eu-anti-GST. 2. Tracer 178. 50. A. Dasatinib. 22.2. Kinase Buffer A: 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA.
http://www.invitrogen.com/etc/medialib/en/filelibrary/Drug-D...
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Abgent Antibodies and Peptides
AP2111b, UBE4B (C-term), IHC, E, H. AP2111a, UBE4B (N-term), WB, IHC, E, H, M. AP6290a, VEGF1 (N-term), WB, IHC, E, H. AP7823b, ZAK (C-term), IHC, E, H ...
http://www.abgent.com/docs/kits_apoptosis...
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Search Bioportfolio and other Life Science Sites for ZAK,
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