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ABCB4


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Symbol:ABCB4
Name(s):ATP-binding cassette, sub-family B (MDR/TAP), member 4
Type:protein-coding
Organism:Homo sapiens
Synonyms:ABC21, GBD1, MDR2, MDR2/3, MDR3, PFIC-3, PGY3
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12206920 Observational study of gene-disease association. (HuGE Navigator)
12381474 Observational study of gene-disease association. (HuGE Navigator)
12891548 Observational study of gene-disease association. (HuGE Navigator)
14999697 Observational study of gene-disease association. (HuGE Navigator)
15077010 Observational study of gene-disease association. (HuGE Navigator)
16696816 Observational study of gene-disease association. (HuGE Navigator)
16857572 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17264802 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18083082 Observational study of gene-disease association. (HuGE Navigator)
16763017 Observational study of genotype prevalence. (HuGE Navigator)

View more information from publications.

Recent Publications on ABCB4:

Pubmed Logo
Combined features of low phospholipid-associated cholelithiasis and progressive familial intrahepatic cholestasis 3.
Abstract Adenosine triphosphate-binding cassette, subfamily B, member 4...
21st October, 2009
UPMC Universite Paris, Paris, France. Liver Int. 2009 Oct 19.
DOI Direct Link
The c.504T>C (p.Asn168Asn) polymorphism in the ABCB4 gene as a predisposing factor for intrahepatic cholestasis of pregnancy in Greece.
Abstract Adenosine triphosphate-binding cassette, subfamily B, member 4...
21st October, 2009
Medical Genetics, Athens University Medical School, "Aghia Sophia" Liver Int. 2009 Oct 13.
DOI Direct Link
Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice.
Scavenger receptor class B type I (SR-BI) mediates selective uptake of...
21st October, 2009
Department of Pediatrics, Center for Liver, Digestive and Metabolic Hepatology. 2009 Oct;50(4):1263-72.
DOI Direct Link
Bone marrow transplantation demonstrates medullar origin of CD34(+) fibrocytes and ameliorates hepatic fibrosis in Abcb4(-/-) mice.
Bone marrow (BM)-derived stem cells and CD34(+) fibrocytes are associated...
15th October, 2009
Department of Gastroenterology, Justus-Liebig University Giessen, Giessen, Hepatology. 2009 Sep 9.
DOI Direct Link
Expression of HNF4alpha in the human and rat choroid plexus: implications for drug transport across the blood-cerebrospinal-fluid (CSF) barrier.
BACKGROUND: The choroid plexus consists of highly differentiated...
14th October, 2009
Fraunhofer Institute for Toxicology and Experimental Medicine, Center of BMC Mol Biol. 2009 Jul 3;10:68.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
ABCB4 Gene Mutations in Intrahepatic Cholestasis of Pregnancy and Controls

Patents:

Patents logo
US Patent No.Title
7504225 Reagents and methods for use in cancer diagnosis, classification and therapy
7468244 Polymorphism detection and separation
7291461 Methods for identifying small molecules that modulate premature translation termination and nonsense mRNA decay
7153652 Mismatch repair detection

ABCB4 results (if any) from reagent suppliers

Google CSE Logo
ABCB4 antibody [P3II-26] (ab24108) | Abcam
ABCB4 is a membrane-associated protein and member of the superfamily of ATP- binding cassette (ABC) transporters. ABC proteins transport various molecu...
http://www.abcam.com/ABCB4-antibody-P3II-26-ab24108.html...

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ABCB4 Antibody (Center)
Western blot analysis of anti-ABCB4 Ctr Pab (Cat. #AP6112a) in Mouse Heart tissue lysates. ABCB4 (Arrow) was detected using purified Pab. ...
http://www.abgent.com/products/catalog_no/AP6112a_ABCB4_Anti...

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ABCB4 antibody (ab71792) | Abcam
Rabbit polyclonal to ABCB4. ABCB4 is a membrane-associated protein and member of the superfamily of ATP-binding cassette (ABC) transporters.
http://www.abcam.com/ABCB4-antibody-ab71792.html...

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Abgent - Cell and Structure Antibodies - Cell_structure
AP7809c, A-RAF Antibody (ARAF1) (Center), IHC, E, H. AP6109a, ABCB10 Antibody (N -term), E, H. AP6112a, ABCB4 Antibody (Center), WB, IHC, E, H, M ...
http://www.abgent.com/products/category/cell_function/cell_s...

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ABCB4 antibodies: Signal Transduction > Protein Trafficking ...
ABCB4 antibodies. ... ABCB4 antibody [P3II-26]. Flow Cyt, ICC, WB, IHC-Fr. Specific publication references. Mouse monoclonal ...
http://www.abcam.com/index.html?t=124174&pt=1&c=2240&ei=&mu=...

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Abgent - Cell and Function Antibodies
AP6109a, ABCB10 Antibody (N-term), E, H. AP6110a, ABCB11 Antibody (C-term), WB, IHC, E, H, M. AP6112a, ABCB4 Antibody (Center), WB, IHC, E, H, M ...
http://www.abgent.com/products/category/cell_function...

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Mdr (C-19) Antibody sc-1517
Mouse, Abcb4, 18670, 5 A1, P21440, N/A. Mouse, Abcb1a, 18671, 5 A1, P21447, N/A. Ordering Information. Product Name, Catalog #, Unit, Price, Qty, Wish List ...
http://www.scbt.com/datasheet-1517-mdr-c-19-antibody.html...

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