Recent Publications on : |  |
Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply.
The glycolytic key regulator pyruvate kinase M2 (M2-PK or PKM2) can switch...
Direct Link | 2nd October, 2009
| Department of Cell Metabolism and Differentiation, Institute for
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A survey of proteins encoded by non-synonymous single nucleotide polymorphisms reveals a significant fraction with altered stability and activity.
On average, each human gene has approximately four SNPs (single nucleotide...
Direct Link | 26th August, 2009
| Structural Genomics Consortium, University of Toronto, 101 College Street,
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Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma.
BACKGROUND: Malignant pleural mesothelioma has few effective treatments,...
Direct Link | 15th May, 2009
| Department of Surgery, Division of Thoracic Surgery, Harvard Medical
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Proteomic analysis of homocysteine induced proliferation of cultured neonatal rat vascular smooth muscle cells.
Hyperhomocysteinemia is a common independent risk factor for...
Direct Link | 24th March, 2009
| Department of Stress Medicine, Institute of Health and Environmental
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| The database dbEST correctly predicts gene expression in colon cancer patients.
| 10th March, 2009
| Leibniz Institute for Age Research - Fritz Lipmann Institute
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Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.
BACKGROUND: The thiazolidinediones (TZDs) improve tissue sensitivity to...
Direct Link | 14th February, 2009
| Genomas, Inc., 67 Jefferson St, Hartford, CT, United States.
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| Pyruvate kinase type M2: a key regulator within the tumour metabolome and a tool for metabolic profiling of tumours.
| 14th November, 2008
| ScheBo Biotech AG, Netanyastrasse 3, 35394 Giessen, Germany.
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New roles for pyruvate kinase M2: working out the Warburg effect.
The origins and role of the Warburg effect have remained uncertain for...
Direct Link | 1st October, 2008
| Department of Pharmacology and Cancer Biology, Duke University Medical
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Modulation of M2-type pyruvate kinase activity by the cytoplasmic PML tumor suppressor protein.
The promyelocytic leukemia (PML) tumor suppressor protein accumulates in...
Direct Link | 16th September, 2008
| Laboratory of Molecular Genetics, RIKEN Tsukuba Institute, 3-1-1 Koyadai,
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AIP1, a carbohydrate fraction from Artemisia iwayomogi, modulates the functional differentiation of bone marrow-derived dendritic cells.
Dendritic cells (DCs) are the most potent antigen-presenting cells (APC)...
Direct Link | 30th July, 2008
| Department of Biology, Changwon National University, #9, Sarim-dong,
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Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription.
The Oct-4 gene encodes a transcription factor that plays an important role...
Direct Link | 21st June, 2008
| Department of Life Science, Sogang University, Seoul 121-742, Republic of
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MuRF1-dependent regulation of systemic carbohydrate metabolism as revealed from transgenic mouse studies.
Under various pathophysiological muscle-wasting conditions, such as...
Direct Link | 20th June, 2008
| Institute for Anaesthesiology and Intensive Operative Care, Medical
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Identification of pyruvate kinase type M2 as potential oncoprotein in squamous cell carcinoma of tongue through microRNA profiling.
MicroRNAs (miRNAs) are noncoding RNAs with specific regulatory role in...
Direct Link | 14th June, 2008
| Department of Surgery, Li Ka Shing Faculty of Medicine, The University of
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Pyruvate kinase M2 is a phosphotyrosine-binding protein.
Growth factors stimulate cells to take up excess nutrients and to use them...
Direct Link | 17th April, 2008
| Department of Systems Biology.
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| Significance of the glycolytic pathway and glycolysis related-genes in tumorigenesis of human colorectal cancers.
| 13th February, 2008
| Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical
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