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PLCG1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17991733 |
PLCgamma-mediated activation of PKCepsilon and PKCbetaI and intracellular calcium is involved in EGF-mediated protection of tight junctions from acetaldehyde-induced insult |
| 11353454 |
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) |
| 11409699 |
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) |
| 16764945 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17336371 |
Review discusses how the interaction between PLC-gamma1 and effector proteins plays a key role in on- or off-regulating PLC-gamma1-mediated cellular proliferation independent of its enzymatic activity. |
| 17561467 |
Results suggest that a PLCgamma-STAT1 pathway mediates apoptotic signaling by FGFR3 in genetic dwarfism and chondrogenic cell lines. |
| 17561374 |
Cellular knockdown of protein kinase Cepsilon (PKCepsilon) leads to decreased activation of PLCgamma1 by epidermal growth factor (EGF). EGF induces tyrosine phosphorylation of PKCepsilon as well as its association with EGF receptor and PLCgamma1. |
| 17562871 |
The association of PLCgamma1 with complexes containing GIT1 and beta-Pix is essential for its role in integrin-mediated cell spreading and motility. As a component of this complex, PLCgamma1 is also involved in the activation of Cdc42 and Rac1. |
| 13129935 |
PLC gamma-dependent component of Fc epsilon RI-mediated calcium flux leading to degranulation of mast cells is independent of PI 3-kinase |
| 11956228 |
Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C | →View more information from publications. |
Recent Publications on PLCG1: |  |
Integrative approach for prioritizing cancer genes in sporadic colon cancer.
The current multistep carcinogenesis models of colon cancer do not fully... | 13th August, 2009
| Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale
| Genes Chromosomes Cancer. 2009 Nov;48(11):953-62.
DOI Direct Link |
PLC-gamma1 regulates fibronectin assembly and cell aggregation.
Phospholipase C-gamma1 (PLC-gamma1) mediates cell adhesion and migration... | 21st July, 2009
| Department of Biochemistry, Vanderbilt University School of Medicine, 647
| Exp Cell Res. 2009 Aug 1;315(13):2207-14. Epub 2009 Apr 18.
DOI Direct Link |
Expression of intracellular calcium signalling genes in cattle skin during tick infestation.
It is widely acknowledged that changes in intracellular calcium ion... | 10th June, 2009
| CSIRO Livestock Industries, Queensland Bioscience Precinct, St Lucia QLD,
| Parasite Immunol. 2009 Apr;31(4):177-87.
DOI Direct Link |
A genetic screen for vascular mutants in zebrafish reveals dynamic roles for Vegf/Plcg1 signaling during artery development.
In this work we describe a forward genetic approach to identify mutations... | 6th June, 2009
| Program in Gene Function and Expression, University of Massachusetts
| Dev Biol. 2009 May 15;329(2):212-26. Epub 2009 Mar 6.
DOI Direct Link |
Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1.
A specialized intercellular junction between podocytes, known as the slit... | 27th May, 2009
| Division of Cellular Proteomics (BML) and Department of Oncology,
| J Biol Chem. 2009 Mar 27;284(13):8951-62. Epub 2009 Jan 29.
DOI Direct Link |
→View more research publications. |
PLCG1 results (if any) from reagent suppliers | 
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Phospho-PLCg1 (Tyr783) Antibody
Antibody detects PLCg1 only when phosphorylated at. Tyr783. It does not cross- react with ... Tyr783 of human PLCg1. Antibodies are purified by protein ...
http://www.cellsignal.com/pdf/2821.pdf...
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PLCG1 Antibody
Specific antibody for the gene product of PLCG1, the protein Phospholipase C gamma 1. Validated for specificity by gene-silencing with siRNA followed by ...
http://www.piercenet.com/products/Browse.cfm?fldID=96C6F6AB-...
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PLCg Antibody Sampler Kit
5) and Ramos (lanes 2, 4, 6) cells, using PLCg1 Antibody. #2822 (lanes 1 and 2), ... while PLCg1 Antibody #2822 is specifc to the 160 kDa PLCg1 ...
http://www.cellsignal.com/pdf/3860.pdf...
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P8104 Anti-Phospholipase Cγ1 antibody produced in rabbit affinity ...
microarray: suitable. Gene Information, human ... PLCG1(5335). rat ... Plcg1( 25738). mouse ... Plcg1(18803). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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Phospho-PLCg2 (Tyr759) Antibody
leads to the phosphorylation of PLCg1 at Tyr771, 783 and ... enzymatic activity of PLCg1 (8). PLCg2 is engaged in antigen-dependent signaling in B cells ...
http://www.cellsignal.com/pdf/3874.pdf...
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Antibodies to Lipids in Cell Signaling
PLCG1(5335) rat ... Plcg1(25738) mouse ... Plcg1(18803), mouse, human, ARR, IP, WB, pricing ... PLCG1(5335), human, bovine, rat, frog (Xenopus laevis) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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Phospho-PLCg2 (Tyr1217) Antibody
enzymatic activity of PLCg1 (8). PLCg2 is engaged in antigen-dependent signaling in B cell ... Phospho-PLCg1 (Tyr783) Antibody #2821. PLCg1 Antibody #2822 ...
http://www.cellsignal.com/pdf/3871.pdf...
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