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EDG8


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Gene DB Home
Symbol:EDG8
Name(s):endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
Type:protein-coding
Organism:Homo sapiens
Synonyms:Edg-8, S1P5, S1PR5, SPPR-1, SPPR-2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17918267 FTY720 induces time-dependent modulation of S1P receptors on human OPCs with consequent functional responses that are directly relevant for the remyelination process.
12234605 differences between hS1P(5) and rS1P(5) will be an important point to be considered in the development of selective receptor antagonists.
12427546 identify and characterize the gene; describe its expression in normal tissues and large granular lymphocyte leukemia monocytes
11705398 The molecular identity, functional properties, and expression profile of the S1P5 (Edg-8) receptor have been characterized.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDG protein, alpha inhibiting 1endothelial differentiation, sphingolipid G-protein-coupled receptor, 8--Pubmed
HPRDguanine nucleotide binding protein, alpha inhibiting activity polypeptide 1Endothelial differentiation gene 8--Pubmed
HPRDguanine nucleotide binding protein, alpha activating polypeptide O isoform aEndothelial differentiation gene 8--Pubmed

Patents:

Patents logo
US Patent No.Title
7611851 Canis sphingosine 1-phosphate receptor isoform 1
7063966 Chimeric G protein coupled receptors
7141383 EDG8 receptor, its preparation and use
7169817 Bis-aromatic alkanols
7199142 1-((5-aryl-1,2,4-oxadiazol-3-yl) benzyl)azetidine-3-carboxylates and 1-((5-aryl-1,2,4-oxadiazol-3-yl)benzyl) pyrrolidine-3-carboxylates as edg receptor agonists

View more patents.

EDG8 results (if any) from reagent suppliers

Google CSE Logo
EDG-8 Antibody / EDG-8 Antibodies
EDG-8 Antibody / EDG-8 Antibodies. ... EDG-8 specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-edg-8.html...

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Cayman Chemical | S1P5 Polyclonal Antibody | Description • EDG-8 ...
EDG-8 acts as a receptor for the bioactive sphingolipid S1P as well as for lysophosphatidic acid (LPA) and gives diverse physiological effects on most
types ...
http://www.caymanchem.com/app/template/Product.vm/catalog/13...

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EDG-8 (H-88) Antibody sc-25493
rabbit polyclonal IgG, 200 µg/ml; epitope corresponding to amino acids 311-398 mapping at the C-terminus of EDG-8 of human origin; recommended for detection
...
http://www.scbt.com/datasheet-25493-edg-8-h-88-antibody.html...

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Sphingosine 1 Phosphate Receptor 5 CT (EDG-8) Blocking Peptide
Example: 10 µl or 10 µg of Exalpha's rabbit anti-EDG8 (S1P5) (CT) (Cat. No. ... Blocking peptide for use in Western blotting with Anti-EDG8 (S1P5) ...
http://www.exalpha.com/pdfs/X1228B.pdf...

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EDG-8 (G-13) Antibody sc-16093
goat polyclonal IgG, 200 µg/ml; epitope mapping within an internal region of EDG -8 of human origin; recommended for detection of EDG-8 of human and, ...
http://www.scbt.com/datasheet-16093-edg-8-g-13-antibody.html...

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Exalpha Biologicals, Inc.
X1228B, Sphingosine 1 Phosphate Receptor 5 CT (EDG-8), Blocking Peptide, 50 µg, $110, Datasheet (pdf) · C176M, Sphingosine 1 Phosphate 3 Receptor (EDG-3) CT ...
http://www.exalpha.com/Searchresults1.php?menuvalue=Category...

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EDG-8 siRNA (m) sc-39931
Click here for details. contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: EDG-8 (m)-PR: sc-39931-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-39931-edg-8-sirna-m.html...

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