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TLR9


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Gene DB Home
Symbol:TLR9
Name(s):toll-like receptor 9
Type:protein-coding
Organism:Homo sapiens
Synonyms:CD289
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18208876 Observational study of gene-disease association. (HuGE Navigator)
18275280 Observational study of gene-disease association. (HuGE Navigator)
18312481 Observational study of gene-disease association. (HuGE Navigator)
17894360 polymorphism of TLR9 gene is significantly associated patients with mold infections, suggesting a possible role for this genetic variant as a risk factor for mold infections in pediatric patients receiving chemotherapy for hematological diseases
18036648 Autocrine TNF-alpha secretion resulting from IgE/FcepsilonRI-dependent activation plays a critical role in suppressing TLR9-dependent responses in plasmacytoid dendritic cells that normally promote T(H)1 activity
17854755 Patients with severe and mild malaria showed increased surface expression of TLR2 and TLR4 on CD14(+)monocytes and myeloid dendritic cells and decreased intracellular expression of TLR9 on plasmacytoid dendritic cells compared to healthy controls.
18092352 Benign prostate epithelial cells express both TLR 4 (LPS-specific) and TLR 9 (CpG-specific) when exposured to lipopolysaccharide (LPS) and CpG DNA.
12573264 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
14987294 Observational study of gene-disease association. (HuGE Navigator)
15730519 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDToll like receptor 9single Ig IL-1R-related molecule--Pubmed
HPRDtoll-like receptor 9 isoform A precursorring finger protein 216 isoform a--Pubmed

BioNews Results for TLR9

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Idera Pharmaceuticals Presents Preclinical Data on IMO-2125, its Lead Drug Candidate for Chronic Hepatitis C V
Therapeutics Daily:  Nov 3 2009 5:20PM Matching: tlr9
Idera Pharmaceuticals Presents Preclinical Data on IMO-2125, its Lead Drug Candidate for Chronic Hepatitis C V
Pharma Live:  Nov 3 2009 5:09PM Matching: tlr9
Idera Pharma (IDRA) Presents IMO-2125 Preclinical Data
Street Insider:  Nov 3 2009 2:53PM Matching: tlr9
Idera Pharmaceuticals Presents Preclinical Data on IMO-2125, its Lead Drug Candidate for Chronic Hepatitis C V
Genetic Engineering News:  Nov 3 2009 1:57PM Matching: tlr9
Idera Pharmaceuticals Presents Preclinical Data on IMO-2125, its Lead Drug Candidate for Chronic Hepatitis C V
Business Wire:  Nov 3 2009 1:23PM Matching: tlr9
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Safety Study of SD-101 (a Novel C Type TLR9 Agonist) for the Treatment of Chronic Hepatitis C Virus (HCV) Infection

Patents:

Patents logo
US Patent No.Title
7470674 Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides
7521443 Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
7521444 Compounds for the treatment of hepatitis C
7524827 Methods and compositions for the inhibition of gene expression
7524828 Immunostimulatory nucleic acid molecules

View more patents.

TLR9 results (if any) from reagent suppliers

Google CSE Logo
PE anti-human TLR9 antibody: r-phycoerythin (r-PE) conjugated anti ...
eBioscience technical data sheet for product 12-9099 PE anti-human Toll-like receptor 9 (CD289, TLR9, TLR-9) eB72-1665 antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_12/12-...

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The Abcam catalog
TLR9 antibodies. ... TLR9 antibody - Aminoterminal end. IHC-P, ICC, WB ... TLR9 antibody - Cytoplasmic domain. Flow Cyt, IHC-P, WB, ICC/IF, IHC-Fr ...
http://www.abcam.com/index.html?t=73449&pt=1&c=480...

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TLR9 (5G5) Antibody sc-47723
See how others have used TLR9 (5G5): sc-47723 antibody and or TLR9 (5G5) ... Western blot analysis of TLR9 expression in RAW 309 Cr.1 whole cell lysate. ...
http://www.scbt.com/datasheet-47723-tlr9-5g5-antibody.html...

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TLR9 antibody [5G5] (ab16892) | Abcam
Mouse monoclonal [5G5] to TLR9. TLR9 is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and ...
http://www.abcam.com/TLR9-antibody-5G5-ab16892.html...

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TLR9 Antibody (IN) Toll-like receptor
TLR9 antibody can be used for detection of TLR9 by Western blot at 0.5 to 1 ug/ ml.,
http://www.prosci-inc.com/shop/catalog1/TLR9-Antibody-p-6351...

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mouse TLR9 antibody, Affinity Purified conjugate
eBioscience technical data sheet for product 14-9092 Purified anti-mouse Toll- like receptor 9 (CD289, TLR9, TLR-9) polyclonal Polyclonal antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_14/14-...

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TLR9 Antibody (CT) Toll-like receptor
TLR9 antibody can be used for detection of TLR9 by Western blot at 1 to 2 ug/ml,
http://www.prosci-inc.com/shop/catalog1/TLR9-Antibody-p-6350...

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