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TLR9


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Gene DB Home
Symbol:TLR9
Name(s):toll-like receptor 9
Type:protein-coding
Organism:Homo sapiens
Synonyms:CD289
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18208876 Observational study of gene-disease association. (HuGE Navigator)
18275280 Observational study of gene-disease association. (HuGE Navigator)
18312481 Observational study of gene-disease association. (HuGE Navigator)
17894360 polymorphism of TLR9 gene is significantly associated patients with mold infections, suggesting a possible role for this genetic variant as a risk factor for mold infections in pediatric patients receiving chemotherapy for hematological diseases
18036648 Autocrine TNF-alpha secretion resulting from IgE/FcepsilonRI-dependent activation plays a critical role in suppressing TLR9-dependent responses in plasmacytoid dendritic cells that normally promote T(H)1 activity
17854755 Patients with severe and mild malaria showed increased surface expression of TLR2 and TLR4 on CD14(+)monocytes and myeloid dendritic cells and decreased intracellular expression of TLR9 on plasmacytoid dendritic cells compared to healthy controls.
18092352 Benign prostate epithelial cells express both TLR 4 (LPS-specific) and TLR 9 (CpG-specific) when exposured to lipopolysaccharide (LPS) and CpG DNA.
12573264 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
14987294 Observational study of gene-disease association. (HuGE Navigator)
15730519 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDToll like receptor 9single Ig IL-1R-related molecule--Pubmed
HPRDtoll-like receptor 9 isoform A precursorring finger protein 216 isoform a--Pubmed

BioNews Results for TLR9

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Idera Pharmaceuticals Initiates Phase 1 Clinical Trial of IMO-2125, a TLR9 Agonist, in Combination with Ribavirin for Chronic Hepatitis C Virus Infection
Pharmaceutical Online:  Oct 9 2009 7:15PM Matching: tlr9
Idera Pharmaceuticals Initiates Phase 1 Clinical Trial Of IMO-2125, A TLR9 Agonist, In Combination With Ribavi
Medical News Today:  Oct 9 2009 9:41AM Matching: tlr9
In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses
Nature Chemical Biology:  Oct 8 2009 9:09PM Matching: tlr9
Idera Pharmaceuticals Initiates Phase 1 Clinical Trial of IMO-2125, a TLR9 Agonist, in Combination with Ribavi
National AIDS Treatment Advocacy Project:  Oct 8 2009 10:37AM Matching: tlr9
Idera Pharmaceuticals, Inc. (IDRA) Initiates Phase 1 Clinical Trial of IMO-2125, a TLR9 Agonist, in Combinatio
BioSpace:  Oct 8 2009 12:54AM Matching: tlr9
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Safety Study of SD-101 (a Novel C Type TLR9 Agonist) for the Treatment of Chronic Hepatitis C Virus (HCV) Infection

Patents:

Patents logo
US Patent No.Title
7442547 Dendritic cells and the uses thereof in screening cellular targets and potential drugs
7517864 RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
7517872 Compounds for the treatment of hepatitis C
7521442 Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
7521443 Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors

View more patents.

TLR9 results (if any) from reagent suppliers

Google CSE Logo
PE anti-human TLR9 antibody: r-phycoerythin (r-PE) conjugated anti ...
eBioscience technical data sheet for product 12-9099 PE anti-human Toll-like receptor 9 (CD289, TLR9, TLR-9) eB72-1665 antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_12/12-...

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The Abcam catalog
TLR9 antibodies. ... TLR9 antibody - Aminoterminal end. IHC-P, ICC, WB ... TLR9 antibody - Cytoplasmic domain. Flow Cyt, IHC-P, WB, ICC/IF, IHC-Fr ...
http://www.abcam.com/index.html?t=73449&pt=1&c=480...

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TLR9 (5G5) Antibody sc-47723
See how others have used TLR9 (5G5): sc-47723 antibody and or TLR9 (5G5) ... Western blot analysis of TLR9 expression in RAW 309 Cr.1 whole cell lysate. ...
http://www.scbt.com/datasheet-47723-tlr9-5g5-antibody.html...

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TLR9 antibody [5G5] (ab16892) | Abcam
Mouse monoclonal [5G5] to TLR9. TLR9 is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and ...
http://www.abcam.com/TLR9-antibody-5G5-ab16892.html...

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TLR9 Antibody (IN) Toll-like receptor
TLR9 antibody can be used for detection of TLR9 by Western blot at 0.5 to 1 ug/ ml.,
http://www.prosci-inc.com/shop/catalog1/TLR9-Antibody-p-6351...

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Polyclonal Antibody to TLR9/CD289
This antibody was developed against a KLH-conjugated synthetic peptide corresponding to part of the extracellular domain of mouse TLR9, ...
http://www.imgenex.com/tds/IMG-431.pdf...

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TLR9 Antibody (CT) Toll-like receptor
TLR9 antibody can be used for detection of TLR9 by Western blot at 1 to 2 ug/ml,
http://www.prosci-inc.com/shop/catalog1/TLR9-Antibody-p-6350...

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