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SEPT5


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Gene DB Home
Symbol:SEPT5
Name(s):septin 5
Type:protein-coding
Organism:Homo sapiens
Synonyms:CDCREL, CDCREL-1, CDCREL1, H5, PNUTL1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17625225 Our finding suggests a role for members of the septin family in the development of proliferative retinal membranes.
14530399 CDCrel-1 overexpression exerts dopamine-dependent neurotoxicity and may contribute to the development of autosomal-recessive juvenile parkinsonism
15214843 We studied the assembly of three human septins, SEPT4, SEPT5 and SEPT8, with each other (heterotypic) and with themselves (homotypic) using a yeast two-hybrid system.
16179808 the high expression levels of PNUTL1 in human pancreatic endocrine cells that suggests a similar role of this protein in islet cells to that demonstrated in neuronal tissues, and warrants further functional studies of this protein.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDNEDD5septin 5--Pubmed
HPRDseptin 2Septin 5--Pubmed
HPRDParkinseptin 5--Pubmed
HPRDparkin isoform 1Septin 5--Pubmed
HPRDSeptin 5syntaxin 1A--Pubmed
HPRDSeptin 5syntaxin 4--Pubmed
HPRDseptin 5Syntaxin 1A--Pubmed
HPRDseptin 5Syntaxin 4A--Pubmed
HPRDseptin 5SEPT8 protein--Pubmed
BINDseptin 5septin SEPT8_v3SEPT5 interacts with SEPT8.-Pubmed

Recent Publications on SEPT5:

Pubmed Logo
Expression pattern of the septin gene family in acute myeloid leukemias with and without MLL-SEPT fusion genes.
Septins are proteins associated with crucial steps in cell division and...
15th September, 2009
Department of Genetics, Portuguese Oncology Institute, Porto, Portugal. Leuk Res. 2009 Sep 11.
DOI Direct Link
[Diverse physiological functions of the septin system: the protean cytoskeleton]
Septins are proteins associated with crucial steps in cell division and...
4th September, 2009
Tanpakushitsu Kakusan Koso. 2009 Jul;54(9):1150-8.
Septins, a novel group of GTP-binding proteins: relevance in hemostasis, neuropathology and oncogenesis.
Septins are a novel family of GTP-binding proteins which are essential for...
22nd August, 2009
University Hospital Freiburg, Department of Paediatrics and Adolescent Klin Padiatr. 2009 May-Jun;221(3):150-5. Epub 2009 May 12.
DOI Direct Link
Sept5 deficiency exerts pleiotropic influence on affective behaviors and cognitive functions in mice.
Deletion or duplication of the human chromosome 22q11.2 is associated with...
15th July, 2009
Department of Psychiatry and Behavioral Sciences, Albert Einstein College Hum Mol Genet. 2009 May 1;18(9):1652-60. Epub 2009 Feb 24.
DOI Direct Link
Whole genome analysis of the action of interferon-beta.
OBJECTIVES: To characterize the IFNbeta1a-regulated gene expression on...
1st July, 2009
Bio Sidus Int J Clin Pharmacol Ther. 2009 May;47(5):328-57.

View more research publications.

SEPT5 results (if any) from reagent suppliers

Google CSE Logo
Septin 5 (SP18) Antibody sc-20040
Cyclin-dependent kinase 5 phosphorylation of human septin SEPT5 (hCDCrel-1) modulates exocytosis. J Neurosci. 28(14): 3631-3643. View PubMed Entry ...
http://www.scbt.com/datasheet-20040-septin-5-sp18-antibody.h...

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Parkin antibody, Parkin Antibody, Rabbit Polyclonal Antibody
Interacts and regulates the turnover of SEPT5. Part of a complex, including STUB1, HSP70 and GPR37. The amount of STUB1 in the complex increases during ER
...
http://www.genwaybio.com/product_info.php?products_id=196411...

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VAMP2 antibody (ab3347) | Abcam
Cyclin-dependent kinase 5 phosphorylation of human septin SEPT5 (hCDCrel-1) modulates exocytosis. J Neurosci 28:3631-43 (2008). PubMed: 18385322 ...
http://www.abcam.com/vamp2-antibody-ab3347.html...

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Septin 3 (G-6) Antibody sc-74431
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, SEPT5, 5413, 22q11.21, NM_002688 ...
http://www.scbt.com/datasheet-74431-septin-3-g-6-antibody.ht...

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Estrogen Receptor (ER [1D5])
Sept 5;277. (5331):1508-1510. 2. Center for Disease Control Manual. Guide: Safety Management,. NO. CDC-22, Atlanta, GA. April 30, 1976 "Decontamination of
...
http://www.biocare.net/antibody-datasheets/054.pdf...

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Syntaxin 1 (HPC-1) Antibody sc-12736
Cyclin-dependent kinase 5 phosphorylation of human septin SEPT5 (hCDCrel-1) modulates exocytosis. J Neurosci. 28(14): 3631-3643. PubMed Entry 보기 ...
http://www.scbt.com/ko/datasheet-12736-syntaxin-1-hpc-1-anti...

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Cell Biology: primary antibodies, proteins, peptides, kits | Abcam
... RACGAP1 proteins and peptides (1) · RCC2 antibodies (4) · SEPT1 antibodies ( 2) · SEPT10 antibodies (1) · SEPT12 antibodies (2) · SEPT5 antibodies (2) ...
http://www.abcam.com/index.html?cl=246&pageconfig=productmap...

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