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PODXL
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16434482 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17719804 |
A 2315-Da peptide found only in medium from SFC colon cancer cell lines was identified and shown to consist of a portion of both the extracellular and transmembrane regions of human podocalyxin-like 1. |
| 16434482 |
PODXL variants are implicated in prostate neoplasm aggressiveness, with gene mapping to chromosome 7q32-q33. |
| 15226400 |
podocalyxin has a role in defining the structure of the podocyte basal surface |
| 15289306 |
Overexpression of the anti-adhesin podocalyxin is associated with breast cancer progression |
| 17616675 |
podocalyxin leads to increased in vitro migration and invasion, increased MMP expression, and increased activation of MAPK and PI3K activity in MCF7 and PC3 cells through its ability to form a complex with ezrin |
| 16684343 |
Transcriptional regulation of Podxl is supported primarily by Sp1 site(s) and that DNA-methylation of the CpG promoter islands contributes to control the tissue specific expression of podxl. |
| 17137615 |
44% of pancreatic ductal adenocarcinomas expressed PODXL-1 in a membranous pattern, and there was no expression in intrahepatic cholangiocarcinomas, rarely in adenocarcinomas of the extrahepatic bile ducts, and none in duodenal adenocarcinomas. |
| 17124010 |
Embryonal carcinoma expresses two distinct forms of podocalyxin, and the larger version is a molecular carrier of the human stem cell-defining antigens TRA-1-60 and TRA-1-81. [TRA-1-60 AND TRA-1-81 AND podocalyxin] |
| 17311105 |
Podocalyxin defines apical membrane domains and is a potent inducer of microvillus formation | →View more information from publications. |
Recent Publications on PODXL: |  |
Ventricular enlargement associated with the panneural ablation of the podocalyxin gene.
Podocalyxin (Podxl) is a type I membrane mucin-protein of the CD34 family... | 20th October, 2009
| Centro de Investigacion Biomedica en Red de Enfermedades Raras (CIBERER),
| Mol Cell Neurosci. 2009 Oct 22.
DOI Direct Link |
Defined and serum-free media support undifferentiated human embryonic stem cell growth.
Four commercially available serum-free and defined culture media tested on... | 19th August, 2009
| Bioprocessing Technology Institute, Stem Cell Group, Singapore, Singapore;
| Stem Cells Dev. 2009 Aug 17.
DOI Direct Link |
Stem cell marker expression in small cell lung carcinoma and developing lung tissue.
Histopathologic and clinical findings suggest that small cell lung cancer... | 14th August, 2009
| Institut of Pathology, University of Bonn, Bonn, Germany.
| Hum Pathol. 2008 Nov;39(11):1597-605. Epub 2008 Jul 24.
DOI Direct Link |
Gene expression profiling of alpha-radiation-induced rat osteosarcomas: identification of dysregulated genes involved in radiation-induced tumorigenesis of bone.
To better understand the molecular basis of radiation-induced osteosarcoma... | 23rd July, 2009
| Laboratoire de Cancerologie Experimentale, iRCM, DSV, CEA,
| Int J Cancer. 2009 Aug 1;125(3):612-20.
DOI Direct Link |
Ubiquitous yet distinct expression of podocalyxin on vascular surfaces in normal and tumor tissues in the rat.
BACKGROUND/AIMS: The vasculature has become an important target in the... | 10th July, 2009
| The Sidney Kimmel Cancer Center, San Diego, Calif. 92121, USA.
| J Vasc Res. 2009;46(4):311-24. Epub 2009 Jan 10.
DOI Direct Link |
→View more research publications. |
PODXL results (if any) from reagent suppliers | 
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Human Embryonic Stem Cell Marker Antibody Panel Plus
25 mg of lyophilized mouse anti-PODXL monoclonal antibody, ... anti-mouse IgG secondary antibody for CD9, E-Cadherin, PODXL, and SSEA-4 (Caltag, ...
http://www.rndsystems.com/pdf/SC009.pdf...
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PODXL antibodies: Stem Cells > Hematopoietic Progenitors > Surface ...
PODXL antibodies. ... PODXL antibody. WB, ELISA. Images. Rabbit polyclonal. Reacts with: Hu. Terms and conditions · Legal · Privacy policy ...
http://www.abcam.com/index.html?t=126766&pt=1&c=3568&ei=&mu=...
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Immunohistochemistry : Podocalyxin - R&D Systems
Detection of PODXL in paraffin-embedded human kidney tissue sections using 5 µg/ mL of R&D Systems goat anti-human PODXL affinity-purified polyclonal ...
http://www.rndsystems.com/ihc_molecule_images.aspx?m=2000...
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PODXL proteins and peptides: Stem Cells > Hematopoietic ...
PODXL proteins and peptides. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab80090 · PODXL protein (His tag). SDS-PAGE, WB ...
http://www.abcam.com/index.html?t=126766&pt=2&c=3568&ei=&mu=...
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Embryonic Stem Cell Biology Antibodies
HPA002110, Anti-PODXL antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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Podocalyxin-like 1 (K-19) Antibody sc-10503
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, PODXL, 5420, 7q32.3, NM_001018111, ...
http://www.scbt.com/datasheet-10503-podocalyxin-like-1-k-19-...
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monoclonal antibody template
Podocalyxin, also known as Podocalyxin-like protein-1 (PCLP1 or PODXL), is a type I transmembrane glycoprotein. It belongs to the CD34/Podocalyxin family of
...
http://www.rndsystems.com/pdf/mab1556.pdf...
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