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PROS1
| Symbol: | PROS1 | | Name(s): | protein S (alpha) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | PROS, PS 26, PS21, PS22, PS23, PS24, PS25, PSA | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16607073 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 16720551 |
Observational study of genotype prevalence and gene-disease association. (HuGE Navigator) |
| 16961608 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17938802 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 17938802 |
a large deletion in PROS1 is shown to partly account for deep vein thrombosis with protein S deficiency [case report] |
| 17958742 |
The PROS1 promoter is responsive to progesterone and other progestins via a mechanism involving PGR-B interacting with a progesterone response element |
| 17890957 |
During the second and third gestation trimesters a significant increase (P < 0.05) in FVIII and VWF:Ag levels and a decrease in FPS levels were seen compared with the first trimester. |
| 17849042 |
Focus on PROS1 mutations involved in protein S deficiency/thrombophilia. |
| 16868938 |
The PROS1 mutations would cause misfolding of the Protein S protein, resulting in the impairment of secretion, which is consistent with the type I PS deficiency phenotype. |
| 17157360 |
Association of PROS dimorphism with plasma protein S levels in normal individuals and patients with inherited protein S deficiency was studied. | →View more information from publications. |
Recent Publications on PROS1: |  |
Prevalence of genetic mutations in protein S, protein C and antithrombin genes in Japanese patients with deep vein thrombosis.
INTRODUCTION: Genetic deficiencies of PROS1, PROC, and SERPINC1... | 23rd October, 2009
| National Cardiovascular Center Research Institute, Suita, Osaka, Japan.
| Thromb Res. 2009 May;124(1):14-8. Epub 2008 Oct 26.
DOI Direct Link |
Compound heterozygous mutations in the PROS1 gene responsible for quantitative and qualitative protein S deficiency.
As a paired class homeodomain transcription factor, mutations of PROP1... | 15th October, 2009
| Departments of Bioregulatory Medicine and Blood Transfusion and Cell
| Int J Hematol. 2009 Oct 14.
DOI Direct Link |
Role of the PROS1 gene in thrombosis: lessons and controversies.
As a paired class homeodomain transcription factor, mutations of PROP1... | 8th October, 2009
| Department of Molecular and Experimental Medicine, The Scripps Research
| Expert Rev Hematol. 2008 Oct 1;1(1):9-12.
DOI Direct Link |
Gross deletions/duplications in PROS1 are relatively common in point mutation-negative hereditary protein S deficiency.
Hereditary protein S (PS) deficiency is an autosomal disorder caused by... | 29th September, 2009
| Einthoven Laboratory for Experimental Vascular Medicine, C2-143,
| Hum Genet. 2009 Sep;126(3):449-56. Epub 2009 May 23.
DOI Direct Link |
Lack of Protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis.
Protein S (ProS) is a blood anticoagulant encoded by the Pros1 gene, and... | 5th September, 2009
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| J Clin Invest. 2009 Sep 1. pii: 39325. doi: 10.1172/JCI39325.
DOI Direct Link |
→View more research publications. |
PROS1 results (if any) from reagent suppliers | 
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Protein S (H-90) Antibody sc-25836
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, PROS1, 5627, 3q11.2, NM_000313 ...
http://www.scbt.com/datasheet-25836-protein-s-h-90-antibody....
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FITC CONJUGATED MONOCLONAL ANTIBODY TO HUMAN PROTEIN S (PS)
PROS1. Species. Rat IgG2a. Formulation. 1 ml (100 µg/ml) 0.2 µm filtered FITC conjugated antibody solution in PBS, containing 1% bovine serum ...
http://www.hbt.nl/HM2148F.pdf...
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A0436 Anti-Protein S-Agarose antibody produced in rabbit IgG ...
antibody form, IgG fraction of antiserum. form, buffered aqueous suspension. species reactivity, human. Gene Information, human ... PROS1(5627) ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?lang=en...
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MONOCLONAL ANTIBODY TO HUMAN PROTEIN S (PS)
PROS1. Species. Rat IgG2a. Formulation. 1 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.1% bovine serum albumin and ...
http://www.hbt.nl/HM2148.pdf...
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Antibodies to Human Plasma Proteins
human ... PROS1(5627), human, ARR, WB, pricing. A0436, Anti-Protein S-Agarose antibody produced in rabbit, (polyclonal), IgG fraction of antiserum, human .
...
https://www.sigmaaldrich.com/etc/controller/controller-page....
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3C-3E
Monoclonal Anti-PROS1 antibody produced in mouse clone 3D7, purified immunoglobulin, buffered aqueous solution, 3D7 (monoclonal) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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Blood Coagulation
Protein S/PROS1. H. SDNSF/MCFD2. H M. Serpin A1/a1-Antitrypsin. H M. H. Serpin A5/Protein C Inhibitor. H. H M. Serpin C1/Antithrombin III ...
http://www.rndsystems.com/DAM_public/6116.pdf...
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Search Bioportfolio and other Life Science Sites for PROS1,
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