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KLK10


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Gene DB Home
Symbol:KLK10
Name(s):kallikrein-related peptidase 10
Type:protein-coding
Organism:Homo sapiens
Synonyms:NES1, PRSSL1
Links: Pubmed, Entrez Gene, GeneCards, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11920956 Observational study of gene-disease association. (HuGE Navigator)
17937626 Glucocorticoid receptor-mediated expression of kallikrein 10
14972646 Kallikrein K10 is decreased in cerebrospinal fluid (CSF) of frontotemporal dementia patients and K10 is increased in CSF of Alzheimer patients, compared to control subjects.
16928223 KLK10 expression is up-regulated in CRC and GC and higher expression of KLK10 closely correlates with advanced disease stage, which predicts a poorer prognosis.
16800732 REVIEW of KLK10 gene expression in neoplasm cells
16800735 functional importance of retinoic acid response elements in the hK10 promoter was demonstrated by retinoid induction of hk10 promoter-reporters
11920956 Identification of single nucleotide polymorphisms in the human kallikrein 10 (KLK10) gene and their association with prostate, breast, testicular, and ovarian cancers.
12970725 kallikrein 10 is expressed in the nonmalignant and malignant prostate, with cancer tissues demonstrating slightly lower expression
12087468 Higher expression in breast cancer predicts tamoxifen resistance
14696124 Downregulation of kallikrein 10 is associated with breast cancer

View more information from publications.

Recent Publications on KLK10:

Pubmed Logo
Prediction of ovarian cancer prognosis and response to chemotherapy by a serum-based multiparametric biomarker panel.
Currently, there are no effective biomarkers for ovarian cancer prognosis...
17th October, 2008
Department of Laboratory Medicine and Pathobiology, University of Toronto, Br J Cancer. 2008 Oct 7;99(7):1103-13. Epub 2008 Sep 2.
DOI Direct Link
Co-expression of KLK6 and KLK10 as prognostic factors for survival in pancreatic ductal adenocarcinoma.
Kallikreins play an important role in tumour microenvironment and as...
16th October, 2008
Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Br J Cancer. 2008 Nov 4;99(9):1484-92. Epub 2008 Oct 14.
DOI Direct Link
Kallikreins as microRNA targets: an in silico and experimental-based analysis.
microRNAs (miRNAs) are non-coding RNAs that target specific mRNAs. They...
27th September, 2008
Department of Laboratory Medicine, and the Keenan Research Centre in the Biol Chem. 2008 Jun;389(6):731-8.
DOI Direct Link
Intracellular signaling pathways regulate hormone-dependent kallikrein gene expression.
OBJECTIVES: Our aim was to examine how certain signal transduction...
20th August, 2008
Department of Laboratory Medicine and Pathobiology, University of Toronto, Tumour Biol. 2008;29(2):63-75. Epub 2008 Jun 2.
DOI Direct Link
In silico analysis of gastric carcinoma Serial Analysis of Gene Expression libraries reveals different profiles associated with ethnicity.
Worldwide gastric carcinoma has marked geographical variations and worse...
24th June, 2008
Laboratory of Molecular Pathology and Epidemiology, Centro Investigaciones Mol Cancer. 2008 Feb 27;7:22.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7258971 Methods and compositions for treating urological disorders using carboxypeptidase Z identified as 8263
7199229 Kallikrein gene
7056674 Prediction of likelihood of cancer recurrence

KLK10 results (if any) from reagent suppliers

Google CSE Logo
KLK10 Antibody (N-term)
The gene for KLK10 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a ...
http://www.abgent.com/products/catalog_no/AP6329d/background...

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WH0005655M1 Monoclonal Anti KLK10 antibody produced in mouse clone ...
WH0005655M1 Monoclonal Anti-KLK10 antibody produced in mouse clone 1G8, purified immunoglobulin, buffered aqueous solution.
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...

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KLK Antibody / KLK Antibodies
KLK10 (G-15) Antibody, sc-20386, goat IgG, internal (h), WB, IF, ELISA, m, r, h. KLK10 (I-06) Antibody, sc-100551, mouse IgG1, FL (h), WB, IP, IF, ELISA ...
http://www.scbt.com/table-klk.html...

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HPA017195 Anti KLK10 antibody produced in rabbit Prestige ...
HPA017195 Anti-KLK10 antibody produced in rabbit Prestige Antibodies™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol ...
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...

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View Cart
KLK10 Antibody (Center) Blocking Peptide, BP6329b, 0.1mg, $42.00, $42.00. Shipping, flat fee, $35.00. Tax will be added to the Total after the order is
...
https://www.abgent.com/store/add_to_cart/BP6329b...

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K
HPA017195, Anti-KLK10 antibody produced in rabbit New, affinity isolated antibody, human ... KLK10(5655), human, IHC (p), PA ...
http://www.sigmaaldrich.com/catalog/search/TablePage/1457466...

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Abgent - Chromatin and Regulation Antibodies - Chromatin_regulation
AP1031b, JMJD5 Antibody (C-term), WB, E, H, M. AP6329d, KLK10 Antibody (N-term), E, H. AP7035a, LATS1 Antibody (N-term), WB, IHC, E, H, M, R ...
http://www.abgent.com/products/category/nuclear_signaling/ch...

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Discovery
expressed in breast (KLK5,KLK6,KLK10,KLK13),. skin (KLK5,KLK7,KLK8),and tissues of the cen- ... KLK10. Breast cancer, prostate cancer ...
http://www.qedbio.com/pdf/newsletters/winter2004_newsletter....

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New Tools: Human Tissue Kallikrein Products - R&D Systems
KLK10, Normal Epithelial Cell-Specific 1 (NES1) protein, Breast, Ovarian, Testicular. KLK11, Trypsin-like Serine Protease (TLSP); hippostasin, Ovarian,
...
http://www.rndsystems.com/cb_detail_objectname_FA04_NTHumanT...

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Chromosome 7 - Santa Cruz Biotechnology, Inc.
KLK11 · sc-146540, SD. Klk10 · 69540, 7 B4, NM_133712 · NP_598473 · KLK10 · sc- 41539, SD. Klk9 · 101533, 7 B4, NM_028660 · NP_082936 ...
http://www.scbt.com/chromosome.php?number=7&page=21&species=...

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