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PSAP
| Symbol: | PSAP | | Name(s): | prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | FLJ00245, GLBA, MGC110993, SAP1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17893707 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17961073 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17712477 |
Expression of saposin C-originated saposin C may upregulate AR gene expression and activate the androgen receptor transcriptional function in an androgen-independent manner in prostate cancer cells. |
| 16080200 |
Amplification and overexpression of PSAP was studied in prostatic neoplasms. |
| 16823039 |
determination of crystal structure of human saposins A and C to 2.0 Angstroms and 2.4 Angstroms, respectively and both reveal the compact, monomeric saposin fold |
| 17561962 |
an unglycosylated Sap-B variant, Asn215His, which causes a fatal sphingolipid storage disease, lost the ability to extract membrane lipids at acidic pH in the presence of BMP |
| 17300216 |
FSAP (Factor VII-activating protease) can cleave and inactivate PDGF-BB (platelet-derived growth factor-BB) and thereby inhibits VSMC (vascular smooth-muscle cell) proliferation. |
| 17372201 |
saposin B may facilitate lipid binding to CD1d molecules throughout the endocytic pathway |
| 14674747 |
The structure of saposin C compared to other saposin-fold family members provides an explanation for function variability of this protein family. |
| 15305334 |
There might be a potential pleuripotent regulatory function for prosaposin in prostate cancer. | →View more information from publications. |
Recent Publications on PSAP: |  |
Late domain-independent rescue of a release-deficient Moloney Murine Leukemia Virus by the Ubiquitin ligase Itch.
Moloney Murine Leukemia Virus (MoMLV) Gag utilizes its Late (L) domain... | 30th October, 2009
| Laboratory of Molecular Microbiology, National Institute of Allergy and
| J Virol. 2009 Oct 28.
DOI Direct Link |
Laboratory Induced Aggression: A Positron Emission Tomography Study of Aggressive Individuals with Borderline Personality Disorder.
BACKGROUND: Borderline personality disorder (BPD) is often associated with... | 15th September, 2009
| James J. Peters Veterans Affairs Medical Center, Bronx; Department of
| Biol Psychiatry. 2009 Sep 11.
DOI Direct Link |
Abnormal regulation of TSG101 in mice with spongiform neurodegeneration.
Spongiform neurodegeneration is characterized by the appearance of... | 26th August, 2009
| Department of Biomedical Sciences, Cornell University, Ithaca, NY, USA.
| Biochim Biophys Acta. 2009 Oct;1792(10):1027-35. Epub 2009 Aug 22.
DOI Direct Link |
Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1.
Metastatic tumors can prepare a distant site for colonization via the... | 26th August, 2009
| Vascular Biology Program, Department of Surgery, Children's Hospital
| Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12115-20. Epub 2009 Jul 6.
DOI Direct Link |
Atypical ductal adenocarcinoma of the prostate with endometrioid immunohistological features.
We present the case of a 52-year-old Caucasian male, admitted to our... | 15th August, 2009
| Department of Endourology, Clinical Institute of Urology and Renal
| Chirurgia (Bucur). 2009 May-Jun;104(3):355-8.
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→View more research publications. |
PSAP results (if any) from reagent suppliers | 
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PSAP Antibody / PSAP Antibodies
PSAP Antibody / PSAP Antibodies. ... PSAP specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-psap.html...
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PSAP antibody (ab55624) | Abcam
Mouse monoclonal to PSAP. PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D, which are similar
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http://www.abcam.com/PSAP-antibody-ab55624.html...
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PSAP (N-20) Antibody sc-26023
See how others have used PSAP (N-20): sc-26023 antibody and or PSAP (N-20) ... Western blot analysis of PSAP expression in non-transfected: sc-117752 (A) ...
http://www.scbt.com/datasheet-26023-psap-n-20-antibody.html...
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Prostate Specific Acid Phosphatase (PSAP) Ab-1
Description: Prostatic acid phosphatase (PSAP) is one of the two antigenic markers of prostatic carcinoma, the other being prostate specific antigen. ...
http://www.labvision.com/ab.cfm?first=AntiBody&second=321...
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PSAP (C-18) Antibody sc-26025
Additional PSAP Antibodies . ... PSAP shRNA (h) Lentiviral Particles, sc-44046-V , 200 µl, $595. PSAP shRNA (m) Lentiviral Particles, sc-152533-V, 200 µl ...
http://www.scbt.com/datasheet-26025-psap-c-18-antibody.html...
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Prostate Specific Acid Phosphatase (PSAP) Ab-1 (Clone PASE/4LJ)
Description: Prostatic acid phosphatase (PSAP) is one of the two antigenic markers of prostatic ... activity of PSAP. It reacts with non-neoplastic adult
...
http://www.labvision.com/pdf/321.pdf...
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PSAP (N-20) Antibody sc-26023
PSAP (N-20): sc-26023 antibody 및 PSAP (N-20) antibody conjugates를 사용한 논문 ... Western blot analysis of PSAP expression in mouse brain tissue extract. ...
http://www.scbt.com/ko/datasheet-26023-psap-n-20-antibody.ht...
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