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C11orf30


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Gene DB Home
Symbol:C11orf30
Name(s):chromosome 11 open reading frame 30
Type:protein-coding
Organism:Homo sapiens
Synonyms:EMSY, FLJ90741, GL002, NGEP
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16236351 Findings support the role of EMSY as a key oncogene within the 11q13 amplicon in ovarian cancer.
16145051 These results support the hypothesis that EMSY overexpression can play a role in the genesis of human breast cancer.
16029503 common genetic variation in EMSY does not appear to have a role in development of breast or ovarian cancer
15947784 The crystal structure of residues 1-108 of EMSY at 2.0 A resolution is reported; the structure contains both the ENT domain and the HP1beta/BS69-binding motif.
15978617 report the crystal structure of the ENT domain of EMSY; dimerisation of EMSY mediated by the ENT domain could provide flexibility for it to bind two or more different substrates simultaneously
14651845 The remarkable clinical overlap between sporadic EMSY amplification and familial BRCA2 deletion implicates a BRCA2 pathway in sporadic breast and ovarian cancer.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDbreast cancer 2, early onsetEMSY protein--Pubmed
HPRDzinc finger, MYND domain containing 11 isoform aEMSY protein--Pubmed
HPRDchromobox homolog 1EMSY protein--Pubmed

C11orf30 results (if any) from reagent suppliers

Google CSE Logo
EMSY (A-15) Antibody sc-34995
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, C11orf30, 56946, 11q13.5, NM_020193
...
http://www.scbt.com/datasheet-34995-emsy-a-15-antibody.html...

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EMSY (A-15) Antibody sc-34995
种属, 基因名称, 基因ID, 染色质位置, 亚型(mRNA)即位号码, 蛋白质即位号码, OMIM™ 号码. 人类, C11orf30, 56946, 11q13.5, NM_020193 · Q7Z589 ...
http://www.scbt.com/zh/datasheet-34995-emsy-a-15-antibody.ht...

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EMSY (A-15) Antibody sc-34995
... Numero de Accesion de Isoforma (ARNm), Numero de Accesion de la Proteina, Número de pedido: Humano, C11orf30, 56946, 11q13.5, NM_020193 · Q7Z589 ...
http://www.scbt.com/es/datasheet-34995-emsy-a-15-antibody.ht...

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