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AKR1B10
| Symbol: | AKR1B10 | | Name(s): | aldo-keto reductase family 1, member B10 (aldose reductase) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI, MGC14103 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18056116 |
AKR1B10 regulates the stability of acetyl-CoA carboxylase-alpha and is a novel regulator of the biosynthesis of fatty acid, an essential component of the cell membrane, in breast cancer cells |
| 11703436 |
Meta-analysis of gene-disease association. (HuGE Navigator) |
| 12365083 |
Observational study of gene-disease association. (HuGE Navigator) |
| 12882871 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18087047 |
structural analysis of the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10 |
| 17425679 |
associated with tumor recurrence after surgery and keratinization of squamous cell carcinoma in cervical cancer but not endometrial cancer |
| 17905306 |
a tyrosine residue located in the catalytic site (Tyr48) is a likely candidate to act as proton acceptor upon inhibitor binding, as it occurs deprotonated to a remarkable extent if only the cofactor NADP+ is bound |
| 17597105 |
AKR1B10 may regulate cell proliferation and cellular response to additional carbonyl stress |
| 17300864 |
Inhibition of aldose reductase prevented TNF-alpha-induced activation of protein kinase C and NF-kappaB which resulted in the abrogation of Cox-2 mRNA and protein expression |
| 15928807 |
Aldose reductase might play a role in cell cycle progression of A549 tumor cells. | →View more information from publications. |
AKR1B10 results (if any) from reagent suppliers | 
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AKR1B10 antibody (ab57547) | Abcam
Mouse monoclonal to AKR1B10. ARK1B10 is a NADPH dependant enzyme with an ability to efficiently reduce aliphatic and aromatic aldehydes. A 316 AA protein, ...
http://www.abcam.com/AKR1B10-antibody-ab57547.html...
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Polyclonal Antibody to Aldo-keto reductase family 1 member B10 ...
Due to its ability to convert glucose to sorbitol, AKR1B10 may have a role in ... A portion of amino acids 100-200 of human AKR1B10 protein were used as the
...
http://www.imgenex.com/antibody_details.php?catalog=IMG-5285...
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AKR1B10 (AA-1) Antibody sc-100501
AKR1B10 (AA-1): sc-100501. Immunofluorescence staining of paraformaldehyde-fixed HeLa cells showing cytoplasmic localization. ...
http://www.scbt.com/datasheet-100501-akr1b10-aa-1-antibody.h...
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Polyclonal Antibody to Aldo-keto reductase family 1 member B10 ...
Due to its ability to convert glucose to sorbitol, AKR1B10 may have a role ... Amino acids 60-73 (QEKIQEKAVKREDL) of human AKR1B10 protein were used as the ...
http://www.imgenex.com/tds/IMX-5264.pdf...
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AKR Antibody / AKR Antibodies
AKR1B10 (AA-1) Antibody, sc-100501, mouse IgG2a, FL (h), WB, IP, IF, IHC(P), ELISA, human. AKR1B10 (P-18) Antibody, sc-54352, goat IgG, C-terminus (h) ...
http://www.scbt.com/table-akr.html...
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AKR1B10 antibodies: Cancer > Tumor biomarkers > Enzymes > Other ...
AKR1B10 antibodies. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab47130 · AKR1B10 antibody. ELISA. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=191273&pt=1&c=4392&ei=&mu=...
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AKR1B10 siRNA (h) sc-72341
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: AKR1B10 ...
http://www.scbt.com/ja/datasheet-72341-akr1b10-sirna-h.html...
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