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BACH1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 12872252 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 16430786 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17504528 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17664283 |
Results point to a critical role for BACH1 helicase activity not only in the timely progression through the S phase by association with BRCA1/BRCA2, but also in maintaining genomic stability. |
| 17881434 |
BACH-1 protein levels are low in cells expressing either the human miR-155 or miR-K12-11 of Kaposi's sarcoma-associated herpesvirus. |
| 15464985 |
These results indicated that heme plays an important role in the induction of alpha-globin gene expression through disrupting the interaction of Bach1 and the NA site in HS-40 enhancer in erythroid cells. |
| 12511571 |
Bach1 functions as a hypoxia-inducible repressor for the HO-1 gene, thereby contributing to fine-tuning of oxygen homeostasis in human cells |
| 16530877 |
key role of down-regulation of Bach1 and up-regulation of heme oxygenase 1 in diminishing cytotoxic effects of hepatitis C virus proteins in human hepatocytes. |
| 16724942 |
Reviewer presents the Bach1-heme oxygenase(HO)-1 system as an important defense mechanism against oxidative stress--a mechanism in which Bach1 is a critical regulator of HO-1. |
| 16771696 |
Data show that beta-carotene, combined with cigarette smoke condensate (TAR), regulates heme oxygenase-1 (HO-1) via its transcriptional factor Bach1 and modulates cell growth. | →View more information from publications. |
Recent Publications on BACH1: |  |
A role for Bach1 and HO-2 in suppression of basal and UVA-induced HO-1 expression in human keratinocytes.
Ultraviolet A (UVA) radiation is an oxidizing agent that strongly induces... | 31st October, 2009
| Department of Pharmacy and Pharmacology, The University of Bath, BA2 7AY
| Free Radic Biol Med. 2009 Oct 26.
DOI Direct Link |
FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner.
FANCJ mutations are genetically linked to the Fanconi anemia... | 29th October, 2009
| Laboratory of Molecular Gerontology, Biomedical Research Center, NIA,
| J Biol Chem. 2009 Jul 3;284(27):18458-70. Epub 2009 May 5.
DOI Direct Link |
[Transcriptional regulation of cellular senescence]
The Fanconi anemia (FA) molecular network consists of 15 "FANC" proteins,... | 23rd October, 2009
| Department of Biochemistry, Tohoku University Graduate School of Medicine,
| Seikagaku. 2009 Jun;81(6):502-10.
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Prolonged cigarette smoke exposure decreases heme oxygenase-1 and alters Nrf2 and Bach1 expression in human macrophages: Roles of the MAP kinases ERK(1/2) and JNK.
Tobacco may be involved in the decreased macrophage heme oxygenase-1... | 14th October, 2009
| Inserm U700, Universite Paris 7, Faculte de Medecine Denis Diderot-site
| FEBS Lett. 2009 Nov 3;583(21):3508-18. Epub 2009 Oct 12.
DOI Direct Link |
Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights.
The Fanconi anemia (FA) molecular network consists of 15 "FANC" proteins,... | 30th September, 2009
| Biology and Biotechnology Division, L452, Lawrence Livermore National
| Mutat Res. 2009 Jul 31;668(1-2):54-72. Epub 2009 Feb 21.
DOI Direct Link |
→View more research publications. |
Patents: |  |
| US Patent No. | Title |
| 7595159 | Prediction of Parkinson's disease using gene expression levels of peripheral blood samples |
| 7485308 | 26199, 33530, 33949, 47148, 50226, 58764, 62113, 32144, 32235, 23565, 13305, 14911, 86216, 25206, and 8843 molecules and uses therefor |
| 7442500 | Methods of diagnosing susceptibility to obesity |
| 7235358 | Methods and compositions for diagnosing and monitoring transplant rejection |
| 7026121 | Methods and compositions for diagnosing and monitoring transplant rejection |
→View more patents. |
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