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BAG1


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Gene DB Home
Symbol:BAG1
Name(s):BCL2-associated athanogene
Type:protein-coding
Organism:Homo sapiens
Synonyms:RAP46
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17950682 Modulation of Bag-1 expression can therefore mediate chondrocyte differentiation and turnover
15309313 Observational study of gene-disease association. (HuGE Navigator)
17700523 BAG-1 mRNA internal ribosome entry segment maintains synthesis of BAG-1 protein following exposure of cells to the chemotoxic drug vincristine but not to cisplatin.
17954934 BAG-1 associates with Tau protein in an Hsc70-dependent manner.
17693608 Results suggest that BAG-1 is able to potentiate vitamin D receptor-mediated transactivation by acting as a nuclear chaperone for 1,25(OH)2D3.
17662274 BAG-1L endogenously regulates gene expression by potentiating nuclear hormone receptor function and a role for BAG-1L in 24-hydroxylase regulation of vitamin D metabolism and the cellular response of oral keratinocytes to 1alpha,25-dihydroxyvitamin D3.
17657847 over-expression of BAG1 may play an important role in genesis and development of colon carcinoma
17549665 An antiapoptotic protein, BAG-1, was found to be down-regulated in chewing-tobacco-mediated tongue carcinogenesis.
12049201 BAG-1, an anti-apoptotic tumour marker Review
12874020 BAG-1-mediated resistance to stress-induced growth inhibition is likely to have a major impact on the development and response to therapy of breast cancer.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDandrogen receptor isoform 1BCL2-associated athanogene isoform 1L--Pubmed
HPRDandrogen receptor isoform 1BCL2-associated athanogene isoform 1L--Pubmed
HPRDBAG 1Seven in absentia homolog 1--Pubmed
HPRDBAG 1met proto-oncogene precursor--Pubmed
HPRDBAG 1vitamin D receptor--Pubmed
HPRDBAG 1heparin-binding EGF-like growth factor--Pubmed
HPRDBAG 1v-raf-1 murine leukemia viral oncogene homolog 1--Pubmed
HPRDBAG 1BCL2-like 1 isoform 1--Pubmed
HPRDBCL2-associated athanogene isoform 1LRAF1--Pubmed
HPRDBCL2-associated athanogene isoform 1LHepatocyte growth factor receptor--Pubmed

Recent Publications on BAG1:

Pubmed Logo
Toxoplasma gondii: Simple Duplex RT-PCR Assay for Detecting SAG1 and BAG1 Genes during Stage Conversion in Immunosuppressed Mice.
Toxoplasmic encephalitis (TE) is caused by reactivation of dormant...
27th October, 2009
Department of Protozoology, Faculty of Tropical Medicine, Mahidol Exp Parasitol. 2009 Oct 22.
DOI Direct Link
Short peptides derived from the BAG-1 C-terminus inhibit the interaction between BAG-1 and HSC70 and decrease breast cancer cell growth.
BAG-1, a multifunctional protein, interacts with a plethora of cellular...
6th October, 2009
Cancer Research UK Centre, Cancer Sciences Division, University of FEBS Lett. 2009 Nov 3;583(21):3405-11. Epub 2009 Oct 1.
DOI Direct Link
BAG1 modulates huntingtin toxicity, aggregation, degradation, and subcellular distribution.
Bcl-2-associated athanogene-1 (BAG1) is a multifunctional protein...
29th August, 2009
Department of Neurology, University Hospital Gottingen, Waldweg, J Neurochem. 2009 Nov;111(3):801-7. Epub 2009 Aug 27.
DOI Direct Link
Involvement of adiponectin and leptin in breast cancer: clinical and in vitro studies.
Obesity is a risk factor for breast cancer development. A recent...
8th August, 2009
T Jarde, EA4233, CLARA, CRNH-A, Univ Clermont 1, UFR Pharmacie, Endocr Relat Cancer. 2009 Sep 3.
DOI Direct Link
Visualization of Toxoplasma gondii stage conversion by expression of stage-specific dual fluorescent proteins.
To recognize the stage conversion of Toxoplasma gondii between tachyzoite...
29th July, 2009
Department of Veterinary Parasitological Diseases, Gifu University, Parasitology. 2009 May;136(6):579-88. Epub 2009 Apr 16.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
5744693 Plants having altered floral development
7081340 Gene expression profiling in biopsied tumor tissues
7094873 Polypeptide that interacts with heat shock proteins
7129244 Triazolopyrimidines and related analogs as HSP90-inhibitors
7138401 2-aminopurine analogs having HSP90-inhibiting activity

View more patents.

BAG1 results (if any) from reagent suppliers

Google CSE Logo
Bag1 antibody - Aminoterminal end (ab45411) | Abcam
Rabbit polyclonal to Bag1 - Aminoterminal end. Bag1 is a multifunctional protein that blocks apoptosis and interacts with several types of proteins.
http://www.abcam.com/bag1-antibody-aminoterminal-end-ab45411...

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BAG-1 Antibody (NT) Bcl-2, glucocorticoid receptor, Hsc70
BAG-1 antibody can be used for the detection of BAG-1 by Western blot at 1 – 2 ug/ml. ,
http://www.prosci-inc.com/shop/catalog1/BAG-1-Antibody-p-641...

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Bag1 antibody [Y166] (ab32109) | Abcam
Rabbit monoclonal [Y166] to Bag1. Bag1 is a multifunctional protein that blocks apoptosis and interacts with several types of proteins.
http://www.abcam.com/bag1-antibody-y166-ab32109.html...

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Bag-1 (C-16) Antibody sc-939
See how others have used Bag-1 (C-16): sc-939 antibody and or Bag-1 (C-16) ... BAG-1 prevents stress-induced long-term growth inhibition in breast cancer ...
http://www.scbt.com/datasheet-939-bag-1-c-16-antibody.html...

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Bag1 antibody [SPM232], prediluted (ab17855) | Abcam
Mouse monoclonal [SPM232] to Bag1, prediluted. Bag1 is a multifunctional protein that blocks apoptosis and interacts with several types of proteins.
http://www.abcam.com/bag1-antibody-spm232-prediluted-ab17855...

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Bag-1 (3.10G3E2) Antibody sc-56003
mouse monoclonal IgG1, 200µg/ml; raised against full length Bag-1 of human ... Bag-1 (3.10G3E2): sc-56003. Western blot analysis of Bag-1 expression in HeLa
...
http://www.scbt.com/datasheet-56003-bag-1-3-10g3e2-antibody....

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Bag1 antibodies: Cardiovascular > Atherosclerosis > Apoptosis | Abcam
Bag1 antibodies. ... Bag1 antibody - Carboxyterminal end. WB. Images. Rabbit polyclonal. Reacts with: ... Bag1 antibody [SPM232], prediluted. IHC-P ...
http://www.abcam.com/index.html?t=8932&pt=1&c=4409&ei=&mu=ra...

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