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BAI1


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Symbol:BAI1
Name(s):brain-specific angiogenesis inhibitor 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLJ41988
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12074842 BAI1 was expressed in cerebral neurons but not astrocytes. It was localized in the cytoplasm and cell membrane. BAI1 protein may play an important role in synapse formation and signal transduction
11875720 brain-specific angiogenesis inhibitor 1 over-expression suppresses tumour angiogenesis
12507886 BAI1 was widely expressed in normal brain but was absent in 28 glioma cell lines and in the majority of human glioblastoma investigated. BAI1 expression did not correlate with TP53 status

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDBrain specific angiogenesis inhibitor 1postsynaptic density protein 95--Pubmed
HPRDBrain specific angiogenesis inhibitor 1phytanoyl-CoA 2-hydroxylase interacting protein--Pubmed
HPRDBrain specific angiogenesis inhibitor 1membrane-associated guanylate kinase-related 3 isoform 1--Pubmed
HPRDbrain-specific angiogenesis inhibitor 1 precursorSynapse associated protein 90--Pubmed
HPRDbrain-specific angiogenesis inhibitor 1 precursorBAI1-associated protein 3--Pubmed
HPRDbrain-specific angiogenesis inhibitor 1 precursorBAI1-associated protein 3--Pubmed
HPRDbrain-specific angiogenesis inhibitor 1 precursorBAI1-associated protein 1--Pubmed
HPRDbrain-specific angiogenesis inhibitor 1 precursorBAI1-associated protein 1--Pubmed
HPRDbrain-specific angiogenesis inhibitor 1 precursorBAI1-associated protein 2 isoform 2--Pubmed
HPRDbrain-specific angiogenesis inhibitor 1 precursorBAI1-associated protein 2 isoform 2--Pubmed

Recent Publications on BAI1:

Pubmed Logo
Enhanced Antitumor Efficacy of Vasculostatin (Vstat120) Expressing Oncolytic HSV-1.
Oncolytic viral (OV) therapy is a promising therapeutic modality for brain...
22nd October, 2009
[1] Dardinger Laboratory for Neuro-oncology and Neurosciences, Department Mol Ther. 2009 Oct 20.
DOI Direct Link
The phosphatidylserine receptor TIM-4 does not mediate direct signaling.
Engulfment of apoptotic cells is an active process coordinated by...
19th May, 2009
Beirne B. Carter Center for Immunology Research, University of Virginia, Curr Biol. 2009 Feb 24;19(4):346-51. Epub 2009 Feb 12.
DOI Direct Link
Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism.
Angiogenesis is a critical physiologic process that is appropriated during...
24th March, 2009
Department of Neurosurgery, Laboratory of Molecular Neuro-Oncology, Cancer Res. 2009 Feb 1;69(3):1212-20. Epub 2009 Jan 27.
DOI Direct Link
Apoptotic cell recognition: will the real phosphatidylserine receptor(s) please stand up?
The recognition of phosphatidylserine (PS) on apoptotic cells within...
24th May, 2008
Department of Pediatrics, National Jewish Medical and Research Center, Curr Biol. 2008 Jan 22;18(2):R76-9.
DOI Direct Link
BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module.
Engulfment and subsequent degradation of apoptotic cells is an essential...
15th December, 2007
Department of Cell Biology, University of Virginia, Charlottesville, Nature. 2007 Nov 15;450(7168):430-4.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7612181 Dual variable domain immunoglobulin and uses thereof
7189507 Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
7112426 Human cAMP-dependent protein kinase beta-catalytic subunit
7031199 Semiconductor memory device
6974667 Gene expression profiles in liver cancer

View more patents.

BAI1 results (if any) from reagent suppliers

Google CSE Logo
Anti-BAI1 Polyclonal Antibody
Polyclonal Antibody against BAI1 for use in Immunohistochemistry.
http://www.bioreagents.com/products/productDetails/productDe...

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BAI-1 (C-19) Antibody sc-33462
goat polyclonal IgG, 200 µg/ml; epitope mapping within a C-terminal cytoplasmic domain of BAI-1 of human origin; recommended for detection of BAI-1 of m, ...
http://www.scbt.com/datasheet-33462-bai-1-c-19-antibody.html...

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BAP3 Antibody (NT2) BAI1-associated protein 3
BAP3 antibody can be used for the detection of BAP3 by Western blot at 2 μg/ml.,
http://www.prosci-inc.com/shop/catalog1/BAP3-Antibody-p-6648...

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BAI1 associated protein 2 isoform 3 peptide (509-520) (ab19041 ...
BAI1 associated protein 2 isoform 3 peptide (509-520). BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor ...
http://www.abcam.com/BAI1-associated-protein-2-isoform-3-pep...

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BAI Antibody / BAI Antibodies
BAI-1 (C-19) Antibody, sc-33462, goat IgG, C-terminal (h), WB, IF, ELISA, m, r, h. BAI-1 (H-270) Antibody, sc-66815, rabbit IgG, 81-350 (h), WB, IP, IF, ...
http://www.scbt.com/table-bai.html...

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BAI1 - R&D Systems
BAI1. BAI3 is a seven-pass transmembrane member of the secretin family of G protein-coupled receptors. It is synthesized by neurons of the CNS and likely is
...
http://www.rndsystems.com/molecule_detail.aspx?m=3988...

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BAI-1 (H-270) Antibody sc-66815
rabbit polyclonal IgG, 200µg/ml; epitope corresponding to amino acids 81-350 mapping within an N-terminal extracellular domain of BAI-1 of human origin ...
http://www.scbt.com/ko/datasheet-66815-bai-1-h-270-antibody....

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