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VISA


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Gene DB Home
Symbol:VISA
Name(s):virus-induced signaling adapter
Type:protein-coding
Organism:Homo sapiens
Synonyms:CARDIF, DKFZp666M015, FLJ27482, FLJ41962, IPS-1, KIAA1271, MAVS
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17911629 IPS-1 is an essential component of the pathway relevant to polyinosinic-polycytidylic acid signaling of type I interferon in intestinal epithelial cells.
16585524 HCV infection transiently induces RIG-I- and IPS-1-dependent IRF-3 activation
16153868 Data suggest that VISA is critically involved in both virus-triggered TLR3-independent and TLR3-mediated antiviral interferon signaling.
16731946 HCV NS3-4A cleavage of human MAVS/IPS-1/VISA/Cardif/K1271 results in its dissociation from the mitochondrial membrane and disrupts signaling to the antiviral immune response
17093192 GBV-B NS3/4A protease specifically cleaves VISA and dislodges it from mitochondria, thereby disrupting its function as a RIG-I adaptor and blocking downstream activation of both interferon regulatory factor 3 and nuclear factor kappa B.
16984921 IPS-1, IRF3, and IFNbeta have critical roles in Legionella infection of lung epithelium
16858409 Cardif induces interferon (IFN)alpha through a direct and specific interaction with the TRAF domain of TRAF3, implicating Cardif as the link between cytoplasmic viral receptors and TRAF3.
16707574 HCV blocks the dsRNA signaling by an NS3/4A-independent mechanism, in addition to the NS3/4A-dependent cleavage of MAVS/IPS-1.
16125763 Mitochondrial antiviral signaling (MAVS) mediates the activation of NF-kappaB and IRF 3 in response to viral infection, and transmembrane domain targets MAVS to the mitochondria, implicating a new role of mitochondria in innate immunity.
16177806 KIAA1271 (aka Cardif, MAVS, VISA, IPS-1) has been shown to be targeted by hepatitis c virus (HCV) NS3/4A protease. This cleavage interferes with the Rig-I mediated dsRNA sensing pathway and therefore with the activation of IRF-3.

View more information from publications.

Press Releases on VISA:

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US Discount Online Pharmacy Expressdelivery.biz Can Guarantee Safe and Enjoyable Shopping Experience With buySAFE Certificate 2nd August, 2009 Express Delivery, Inc.

LAS VEGAS, Aug. 2 /PRNewswire/ -- Being certified by online guardian angel buySAFE means that expressdelivery.biz is a trusted merchant and its ability to honor sales terms, as well

VISTAKON(R) Launches ACUVUE(R) DIRECT(TM) 13th May, 2009 VISTAKON, Division of Johnson & Johnson Vision Care, Inc.

Offers more affordable, convenient way to buy annual supply of ACUVUE(R) Brand Contact Lenses

JACKSONVILLE, Fla., May 13 /PRNewswire/ -- VISTAKON(R), a

7th Annual FedEx/St. Jude Angels & Stars Gala Announces 2009 Honorees Tommy Mottola & Thalia 20th April, 2009 St. Jude Children's Research Hospital

MIAMI, April 20 /PRNewswire-USNewswire/ -- The 7th annual FedEx/St. Jude Angels & Stars Gala will be held Saturday, May 16, 2009 at 7:00 p.m. at the InterContinental Miami

PRN Funding Now Accepting Credit Cards 5th December, 2008 PRN Funding, LLC

CLEVELAND, Dec. 5 /PRNewswire/ -- Keeping up with the evolving needs of its clientele, PRN Funding, LLC is now accepting VISA, MasterCard, and American Express credit cards as a form of payment on

Positive Study Results for Ceftaroline Phase III Clinical Study for the Treatment of Complicated Skin and Skin Structure Infections Presented at ICAAC / IDSA 27th October, 2008 Forest Laboratories, Inc.

New Data on Ceftaroline, a Novel, Broad-Spectrum Cephalosporin in Development for Complicated Skin and Skin Structure Infections (cSSSI) and Community Acquired Pneumonia (CAP)

BioNews Results for VISA

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Russian executive underwent chin implant surgery in India
Treatment Abroad:  Nov 14 2009 9:41PM Matching: visa
Canada Will Require Foreign Students to Submit Biometric Data
Chronicle of Higher Education:  Nov 12 2009 4:48AM Matching: visa
China closed to AIDS patients
China Economic Net:  Nov 11 2009 9:48AM Matching: visa
Sequencing, Sequencing, Sequencing
Bio-IT World:  Nov 10 2009 4:33PM Matching: visa
Faith groups welcome lifting of US entry restrictions on people with HIV
Ekklesia:  Nov 6 2009 2:59AM Matching: visa
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

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Study of Soft Contact Lens Use With 7 Day Extended Wear

Patents:

Patents logo
US Patent No.Title
7606766 Computer system and computer-implemented method for selecting invoice settlement options
7608175 Electrochemical cell
7608468 Apparatus and methods for determining overlay and uses of same
7608974 Diamond-like carbon devices and methods for the use and manufacture thereof
7608989 Compliant electroactive polymer transducers for sonic applications

View more patents.

VISA results (if any) from reagent suppliers

Google CSE Logo
VISA Antibody (NT) Virus-induced signaling adapter
VISA antibody can be used for detection of VISA by Western blot at 0.5 – 1 μg/ml .,
http://www.prosci-inc.com/shop/catalog1/VISA-Antibody-p-6497...

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MAVS antibody, Rabbit anti VISA (Middle) Antibody, Rabbit ...
Rabbit anti VISA (Middle); Interferon-beta promoter stimulator protein 1; IPS-1; Virus-induced-signaling adapter; CARD adapter inducing interferon-beta; ...
http://www.genwaybio.com/product_info.php?products_id=244362...

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ATG12 Antibody
proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells (5). ...
http://www.prosci-inc.com/shop/pdf/4421.pdf...

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MAVS Antibody (Rodent Specific) #4983
MAVS Antibody (Rodent Specific) detects endogenous levels of total MAVS/VISA protein. The bands detected at 52 and 75 kDa correlate with those described by
...
http://www.cellsignal.com/products/4983.html...

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ATG5 Antibody Autophagy related protein 5
This conjugate also associates with innate immune response proteins such as RIG- I and VISA (also known as IPS-1), inhibiting type I interferon production ...
http://www.prosci-inc.com/shop/catalog1/ATG5-Antibody-p-6633...

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RanBP1 IHC Antibody Bethyl Laboratories
VISA, MasterCard and American Express or a purchase order are accepted as payment. ... Payment is accepted by check, MasterCard, VISA or American Express
or ...
http://www.bethyl.com/go/?product/ihc-00441...

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Maintenance of Genome Stability Conference 2010 | Abcam
Further information about visa requirements can be found on the World Travel Guide ... American Express, Diners Club, MasterCard and Visa are accepted. ...
http://www.abcam.com/index.html?pageconfig=resource&rid=1152...

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