Friday November 27 2009 | Biotechnology feed | All feeds

XPO5

Symbol:	XPO5
Name(s):	exportin 5
Type:	protein-coding
Organism:	Homo sapiens
Synonyms:	FLJ14239, FLJ32057, FLJ45606, KIAA1291
Links:	Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications
Publication Link	Summary of findings
12426392	Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm.
14631048	exportin-5 is key to microRNA biogenesis and may help coordinate nuclear and cytoplasmic processing steps
15254228	exportin-5 has a role in exporting JAZ from the cell nucleus
12426393	Eukaryotic elongation factor 1A (eEF1A) and tRNA are RanGTP-dependent binding partners of exportin-5 (Exp5). Exp5 stimulates nuclear export of eEF1A and tRNA.
14570900	exportin-5 has a role in nuclear export of ILF3 (interleukin enhancer binding factor 3)

Interacting gene products
Interaction Type	Gene 1	Gene 2	Interaction description	Complex	Publication Link
HPRD	eukaryotic translation elongation factor 1 alpha 1	exportin 5	-	-	Pubmed
HPRD	eukaryotic translation elongation factor 1 alpha 1	exportin 5	-	-	Pubmed
HPRD	interleukin enhancer binding factor 3 isoform a	exportin 5	-	-	Pubmed
HPRD	interleukin enhancer binding factor 3 isoform a	exportin 5	-	-	Pubmed
HPRD	RAN, member RAS oncogene family	exportin 5	-	-	Pubmed
HPRD	ras-related nuclear protein	Exportin 5	-	-	Pubmed
HPRD	nucleoporin 214kDa	exportin 5	-	-	Pubmed
HPRD	nucleoporin 214kDa	exportin 5	-	-	Pubmed
HPRD	Fas-associated via death domain	exportin 5	-	-	Pubmed
HPRD	Fas-associated via death domain	exportin 5	-	-	Pubmed

XPO5 results (if any) from reagent suppliers

Exportin 5 (H-300) Antibody sc-66885 Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, XPO5, 57510, 6p21.1, NM_020750 ... http://www.scbt.com/datasheet-66885-exportin-5-h-300-antibod...
Invitrogen's Stem Cell Technology Platforms - Invitrogen.com a ... Xpo-5. miRNA unwinding nucleus cytoplasm. 26. Characterization – Endogenous miRNA pathway. I. Evolutionarily conserved. II. Gene regulatory function ... http://www.invitrogen.com/etc/medialib/en/filelibrary/pdf.Pa...
Exportin 5 siRNA (m) sc-45570 Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Xpo5, 72322, 17 C, Q924C1 ... http://www.scbt.com/datasheet-45570-exportin-5-sirna-m.html...
Knockdown Deliver Analyze Synthetic RNAi Transfection reagents ... Xpo-5. miRNA. Unwinding. Nucleus. Cytoplasm. miRNA has 100% homology to mRNA, which results in target mRNA cleavage. RISC. Pol II mRNA transcription ... http://www.invitrogen.com/etc/medialib/en/filelibrary/pdf/Ca...
Features Exportin-5 (Xpo-5) transports the pre-miRNA to the cytoplasm, where Dicer liberates a ... Xpo-5. Cytoplasm. Ribosome. RISC. AAAAAA. Nuclease. Cleaved target ... http://www.invitrogen.com/etc/medialib/en/filelibrary/pdf/qu...

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