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G6PC2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17607665 |
missense mutation in exon 4, L173P, found in glycogen storage disease type Ia |
| 16493034 |
This study demonstrates the prevalence of CD4+ IGRP-specific T cells not only in subjects with type I diabetes, but also in healthy individuals carrying the DR0301 or DR0401 haplotypes. |
| 14722102 |
IGRP is likely the authentic islet-specific glucose-6-phosphatase catalytic subunit, and selective inhibitors to this molecule can be obtained |
| 15044018 |
Data show that islet-specific glucose-6-phosphatase-related protein is an endoplasmic reticulum membrane glycoprotein, and is degraded through the proteasome pathway that generates the major histocompatibility complex class I-presented peptides. |
| 16520917 |
Differential tissue expression may aid in designing synthetic peptides for the identification of IGRP-specific autoreactive T cells in patients with type 1 diabetes. |
| 16012821 |
Alpha mutants containing the beta cell antigen sequence are preferentially degraded in cells, which prevents targeting by pathogenic CD8+ T cells implying that IGRP levels in beta cells could dictate susceptibilities to diabetes. |
| 17376840 |
human CD8 T cell clone against this epitope, which confirms that this IGRP epitope is shared across species. |
G6PC2 results (if any) from reagent suppliers | 
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IGRP (N-20) Antibody sc-33471
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, G6PC2, 57818, 2q24.3, NM_021176 ...
http://www.scbt.com/ko/datasheet-33471-igrp-n-20-antibody.ht...
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FabGennix Inc. International >> Products
Glucose-6-Phosphatase Catalytic subunit 2 (G6PC2). Antibodies to Proteinases and Convertases: Antibodies to PCSK9 or Neural Regulated Concertase 1 (NARC1) ...
http://www.fabgennix.com/prod_category.asp?mycategory=ANTIBO...
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IGRP (H-60) Antibody sc-66932
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, G6PC2, 57818, 2q24.3, NM_021176 ...
http://www.scbt.com/ja/datasheet-66932-igrp-h-60-antibody.ht...
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IGRP (H-60) Antibody sc-66932
Humain, G6PC2, 57818, 2q24.3, NM_021176 · NP_066999 · 608058. Souris, G6pc2, 14378, 2 C2, Q9Z186, Non disponible. Produits disponibles ...
http://www.scbt.com/fr/datasheet-66932-igrp-h-60-antibody.ht...
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IGRP (H-60) Antibody sc-66932
种属, 基因名称, 基因ID, 染色质位置, 亚型（mRNA）即位号码, 蛋白质即位号码, OMIM™ 号码. 人类, G6PC2, 57818, 2q24.3, NM_021176 · NP_066999 ...
http://www.scbt.com/zh/datasheet-66932-igrp-h-60-antibody.ht...
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