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PTPRC


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Symbol:PTPRC
Name(s):protein tyrosine phosphatase, receptor type, C
Type:protein-coding
Organism:Homo sapiens
Synonyms:B220, CD45, CD45R, GP180, LCA, LY5, T200
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18312479 Observational study of gene-disease association. (HuGE Navigator)
11528386 Observational study of gene-disease association. (HuGE Navigator)
11548742 Observational study of gene-disease association. (HuGE Navigator)
11841494 Observational study of gene-disease association. (HuGE Navigator)
11862398 Observational study of genotype prevalence. (HuGE Navigator)
12028593 Observational study of gene-disease association. (HuGE Navigator)
12147336 Observational study of gene-disease association. (HuGE Navigator)
12595907 Observational study of gene-disease association. (HuGE Navigator)
12618866 Observational study of genotype prevalence. (HuGE Navigator)
12864992 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCD1dprotein tyrosine phosphatase, receptor type, C isoform 1 precursor--Pubmed
HPRDCD1D antigen precursorProtein tyrosine phosphatase receptor type C--Pubmed
HPRDHuman T-cell surface antigen CD2 mRNA, and translated productsprotein tyrosine phosphatase, receptor type, C isoform 1 precursor--Pubmed
HPRDHuman T-cell surface antigen CD2 mRNA, and translated productsprotein tyrosine phosphatase, receptor type, C isoform 1 precursor--Pubmed
HPRDT-cell receptor zeta chain isoform 1 precursorprotein tyrosine phosphatase, receptor type, C isoform 1 precursor--Pubmed
HPRDT-cell receptor zeta chain isoform 1 precursorprotein tyrosine phosphatase, receptor type, C isoform 1 precursor--Pubmed
HPRDCD4 antigen precursorprotein tyrosine phosphatase, receptor type, C isoform 1 precursor--Pubmed
HPRDCD4 antigen precursorprotein tyrosine phosphatase, receptor type, C isoform 1 precursor--Pubmed
HPRDCD8 Antigen, alpha polypeptideprotein tyrosine phosphatase, receptor type, C isoform 1 precursor--Pubmed
HPRDCD8 antigen alpha polypeptide isoform 1 precursorProtein tyrosine phosphatase receptor type C--Pubmed

Recent Publications on PTPRC:

Pubmed Logo
Purkinje cell loss in experimental autoimmune encephalomyelitis.
Gray matter atrophy observed by brain MRI is an important correlate to...
31st October, 2009
Laboratory of Neuro Imaging, Suite 225, Los Angeles, CA 90095-1769, USA. Neuroimage. 2009 Dec;48(4):637-51. Epub 2009 Jul 6.
DOI Direct Link
Fetal liver very small embryonic/epiblast like stem cells follow developmental migratory pathway of hematopoietic stem cells.
Fetal liver (FL) has been described as a source of both hematopoietic and...
24th October, 2009
Stem Cell Institute at James Graham Brown Cancer Center, University of Ann N Y Acad Sci. 2009 Sep;1176:205-18.
DOI Direct Link
Peptide-major histocompatibility complex dimensions control proximal kinase-phosphatase balance during T cell activation.
T cell antigen recognition requires binding of the T cell receptor (TCR)...
20th October, 2009
Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 J Biol Chem. 2009 Sep 18;284(38):26096-105. Epub 2009 Jul 23.
DOI Direct Link
Change of specific T cells in an emerging neonatal infectious disease induced by a bacterial superantigen.
A new epidemic, NTED, has recently occurred in Japan. The cause of NTED is...
14th October, 2009
Department of Pediatrics, Jichi Medical University School of Medicine, Microbiol Immunol. 2009 Sep;53(9):524-30.
DOI Direct Link
Reduced levels of protein tyrosine phosphatase CD45 protect mice from the lethal effects of Ebola virus infection.
Ebola virus (EBOV) infection of humans is a lethal but accidental dead-end...
10th October, 2009
United States Army Medical Research Institute of Infectious Diseases, 1425 Cell Host Microbe. 2009 Aug 20;6(2):162-73.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
7122345 Nucleic acid encoding a NOVX13 polypeptide
7060275 Use of protein biomolecular targets in the treatment and visualization of brain tumors
7049072 Gene expression analysis of pluri-differentiated mesenchymal progenitor cells and methods for diagnosing a leukemic disease state
7026121 Methods and compositions for diagnosing and monitoring transplant rejection

View more patents.

PTPRC results (if any) from reagent suppliers

Google CSE Logo
PTPRC antibody, CD45 Antibody, Mouse Monoclonal Antibody
Buy quality mouse PTPRC antibody (interacts with human), anti-PTPRC, CD45 antibody, mouse monoclonal antibody, CD45 Antibody, Mouse Monoclonal Antibody
...
http://www.genwaybio.com/product_info.php?products_id=72637...

Thumbshot
PTPRC Rat Anti-Mouse Protein Tyrosine Phosphatase Receptor Type C ...
Rat Anti-Mouse PTPRC Clone 5C16 monoclonal antibody. Isotype: ... PTPRC Immunohistochemistry staining of paraffin sections of mouse kidney and heart
tissues ...
http://www.cellsciences.com/PDF/CMP140.pdf...

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CD45 antibody, CD45 [YW 62.3] (FITC) Antibody, Rat Monoclonal Antibody
Rat Antibody to Mouse CD45 ( Ly - 5 ):FITC; 19264; Ptprc; B220; CD45R; Cd45; Ly- 5; Lyt-4; T200; loc; 5788; PTPRC; 126200; P08575; B220; CD45; GP180; LCA; ...
http://www.genwaybio.com/product_info.php?products_id=193622...

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Antibodies to Human Leukocytes
PTPRC(5788), human, FACS, pricing. R4263, Monoclonal Anti-CD45RO−Quantum Red™ antibody produced in mouse, UCHL-1 (monoclonal), purified immunoglobulin ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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CD45 (H-230) Antibody sc-25590
Human, PTPRC, 5788, 1q31.3, NM_002838, NM_080921, NM_080922, NM_080923 · P08575 · 609532. Mouse, Ptprc, 19264, 1 E4, P06800 ...
http://www.scbt.com/datasheet-25590-cd45-h-230-antibody.html...

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C6555 Monoclonal Anti-CD45RO antibody produced in mouse clone UCHL ...
species reactivity, human. application(s), flow cytometry: 10 μL using 1 × 106 cells. Gene Information, human ... PTPRC(5788). shipped in, wet ice ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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CD45RC (GL24) Antibody sc-52495
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Ptprc, 19264, 1 E4, P06800 ...
http://www.scbt.com/datasheet-52495-cd45rc-gl24-antibody.htm...

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