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BARD1


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Gene DB Home
Symbol:BARD1
Name(s):BRCA1 associated RING domain 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
14550946 Observational study of gene-disease association. (HuGE Navigator)
16333312 Observational study of gene-disease association. (HuGE Navigator)
16672066 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16768547 Observational study of gene-disease association. (HuGE Navigator)
16825437 Observational study of gene-disease association. (HuGE Navigator)
17028982 Observational study of gene-disease association. (HuGE Navigator)
17333333 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17399677 Observational study of genetic testing. (HuGE Navigator)
17972171 Observational study of gene-disease association. (HuGE Navigator)
18089818 BARD1 isoform expression is required for cancer cell proliferation, which is compatible with the notion that BARD1 isoforms act as cancer maintenance genes in gynecological cancers.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDBRCA1 associated ring domain 1cleavage stimulation factor subunit 1--Pubmed
HPRDBRCA1 associated ring domain 1ubiquitin-conjugating enzyme E2L 3 isoform 1--Pubmed
HPRDBRCA1 associated ring domain 1breast cancer 1, early onset isoform 1--Pubmed
BINDHomo sapiens chromosome 2E2F transcription factor 4E2F4 interacts with the BARD1 promoter region.-Pubmed
BINDHomo sapiens chromosome 2E2F transcription factor 1E2F1 interacts with the BARD1 promoter.-Pubmed
HPRDBRCA1 associated RING domain 1BRCA1--Pubmed
HPRDBRCA1 associated RING domain 1CstF 50--Pubmed
HPRDBRCA1 associated RING domain 1Ubiquitin conjugating enzyme E2L3--Pubmed
HPRDBRCA1 associated RING domain 1RBBP8 protein--Pubmed
HPRDBRCA1 associated RING domain 1RBBP8 protein--Pubmed

Recent Publications on BARD1:

Pubmed Logo
Dynamic interactions of proteins in complex networks: identifying the complete set of interacting E2s for functional investigation of E3-dependent protein ubiquitination.
A ubiquitin ligase (E3) functions at the crossroad between ubiquitin...
23rd October, 2009
Department of Biochemistry, University of Utah, Salt Lake City, UT 98195, FEBS J. 2009 Oct;276(19):5381-9. Epub 2009 Aug 27.
DOI Direct Link
Differential modulation of BRCA1 and BARD1 nuclear localisation and foci assembly by DNA damage.
The BRCA1/BARD1 heterodimer regulates genomic maintenance and contributes...
3rd October, 2009
Westmead Institute for Cancer Research, University of Sydney, Westmead Cell Signal. 2009 Sep 29.
DOI Direct Link
Understanding the functions of BRCA1 in the DNA-damage response.
Inheritance of a mutation in BRCA1 (breast cancer 1 early-onset) results...
30th September, 2009
Division of Protein and Nucleic Acids Chemistry, MRC Laboratory of Biochem Soc Trans. 2009 Jun;37(Pt 3):597-604.
DOI Direct Link
Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers.
Inherited BRCA1/2 mutations confer elevated ovarian cancer risk. Knowledge...
26th September, 2009
Abramson Cancer Center, The University of Pennsylvania School of Medicine, Cancer Res. 2009 Jul 15;69(14):5801-10. Epub 2009 Jul 7.
DOI Direct Link
A comparison of BRCA1 nuclear localization with 14 DNA damage response proteins and domains: identification of specific differences between BRCA1 and 53BP1 at DNA damage-induced foci.
BRCA1 is an important mediator of the DNA damage response pathway....
22nd September, 2009
Westmead Institute for Cancer Research, The University of Sydney, Westmead Cell Signal. 2010 Jan;22(1):47-56. Epub 2009 Sep 17.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
6987000 Cark protein and nucleic acid molecules and uses therefor
6951721 Method for determining the haplotype of a human BRCA1 gene
6943245 Tumor suppressor CAR-1
6759046 Peptides

View more patents.

BARD1 results (if any) from reagent suppliers

Google CSE Logo
BARD1 Antibody / BARD1 Antibodies
BARD1 Antibody / BARD1 Antibodies. ... BARD1 specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-bard1.html...

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Anti-BARD1 Polyclonal Antibody
Polyclonal Antibody against BARD1 for use in Immunoprecipitation, Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

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BARD1 (H-300) Antibody sc-11438
See how others have used BARD1 (H-300): sc-11438 antibody and or BARD1 (H-300) ... Ubiquitination and proteasome-mediated degradation of BRCA1 and BARD1 ...
http://www.scbt.com/datasheet-11438-bard1-h-300-antibody.htm...

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BARD1 Bethyl Laboratories
BRCA1 associated RING domain 1 (BARD1) together with BRCA1 is an E3 ubiquitin ligase. BARD1/BRCA1 has been shown to ubiquinate RNA polymerase II in response
...
http://www.bethyl.com/category/BARD1/Antibody/AAAAAAAABAAEAA...

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BARD1 Antibody / BARD1 Antibodies
BARD1 Antibody / BARD1 Antibodies. ... BARD1 spezifische siRNA, sHRNA Plasmide und shRNA Lentivirale Partikel Gen Silencer sind ebenfalls erhältlich. ...
http://www.scbt.com/de/table-bard1.html...

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BARD1 antibodies: Chromatin and Nuclear Signaling > DNA / RNA ...
BARD1 antibodies. ... BARD1 antibody [2059C4a]. IP, WB, Dot. Images. Mouse monoclonal. Reacts with: Hu. Terms and conditions · Legal · Privacy policy ...
http://www.abcam.com/index.html?t=16812&pt=1&c=883&ei=&mu=ra...

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BARD1 (2059C4a) Antibody sc-81195
BARD1 shRNA (h) Lentiviral Particles, sc-37311-V, 200 µl ... BARD1 (2059C4a): sc -81195 Western Blot analysis of human recombinant BARD1 fusion protein. ...
http://www.scbt.com/datasheet-81195-bard1-2059c4a-antibody.h...

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