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RAD1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17855402 |
Human thymine DNA glycosylase activity is significantly stimulated by hHus1, hRad1, hRad9 separately, and by the 9-1-1 complex. |
| 17583730 |
Jab1 physically associates with the 9-1-1 complex; this association is mediated through direct interaction between Jab1 and Rad1, one of the subunits of the 9-1-1 complex |
| 17493829 |
we report successful tri-cistronic cloning, overexpression and purification of a three-protein complex of Rad9, Rad1 and Hus1 using a single hexa-histidine tag. |
| 15871698 |
The long-patch base excision machinery is an important target of the Rad9-Rad1-Hus1 complex, thus enhancing the quality control of DNA. |
| 17395641 |
Human NEIL1 DNA glycosylase activity is significantly stimulated by hRad1 and by the Rad9/Rad1/Hus1 heterotrimer. |
| 15314187 |
The human Rad9/Rad1/Hus1 complex interacts with and stimulates DNA polymerase beta activity. |
| 16216273 |
PCNA and the Rad9/Rad1/Hus1 complex can independently bind and activate Fen1; acetylation of Fen1 by p300-HAT abolished the stimulatory effect of the complex but not that of PCNA, suggesting a possible mechanism of regulation of this repair pathway |
| 15122316 |
RAD1 is a potential intrinsic chaperone in the stabilization of HUS1 for the heterotrimeric (RAD9-RAD1-HUS1) checkpoint complex formation. |
| 15556996 |
complex with rad9 and hus1 is a damage-specific activator of flap endonuclease 1 |
| 16814252 |
These data provide in vivo evidence that the human 9-1-1 complex participates in DNA repair in addition to its previously described role in DNA damage sensing. | →View more information from publications. |
Recent Publications on RAD1: |  |
Msh2 blocks an alternative mechanism for non-homologous tail removal during single-strand annealing in Saccharomyces cerevisiae.
Chromosomal translocations are frequently observed in cells exposed to... | 17th October, 2009
| Division of Molecular Biology, Beckman Research Institute, City of Hope
| PLoS One. 2009 Oct 16;4(10):e7488.
DOI Direct Link |
DNA distress: just ring 9-1-1.
The Rad9-Hus1-Rad1 checkpoint clamp (9-1-1) is a central player in the... | 17th October, 2009
| Department of Biochemistry and Biophysics and Lineberger Comprehensive
| Curr Biol. 2009 Sep 15;19(17):R733-4.
DOI Direct Link |
Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex.
Cellular DNA lesions are efficiently countered by DNA repair in... | 15th October, 2009
| National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese
| J Biol Chem. 2009 Jul 31;284(31):20457-61. Epub 2009 Jun 17.
DOI Direct Link |
Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.
Budding yeast Slx4 interacts with the structure-specific endonuclease Slx1... | 26th September, 2009
| MRC Protein Phosphorylation Unit, College of Life Sciences, University of
| Mol Cell. 2009 Jul 10;35(1):116-27.
DOI Direct Link |
[Validation of a regionalized optometric scale for preschool children: nursing contribution]
A regionalized figure scale (RAD) was developed. The objective was to... | 25th September, 2009
| Universidade Federal do Acre, Rio Branco, AC, Brasil.
| Rev Esc Enferm USP. 2009 Jun;43(2):279-86.
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→View more research publications. |
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