|
| |
PEX5
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15328363 |
the N terminus of Pex5p is required for redirecting the peroxisome-associated peroxin back to the cytosol |
| 12456682 |
binds the PTS1 independently of Hsp70 and the peroxin PEX12 |
| 17399738 |
Results describe the affinities of mutated forms of Pex5p for a series of peroxisomal targeting signal type-1 (PTS1) peptides and conclude that PTS1-affinity reductions are correlated with Zellweger disease severity and cell biological phenotype. |
| 17317787 |
study shows mutation-dependent, gain-of-function association between myocilin & PTS1R; there was correlation between glaucoma phenotype & specific MYOC mutations, with more severe early-onset POAG mutations having higher degree of association with PTS1R |
| 17428317 |
A previously unobserved conformation for PEX5 suggests roles for intrinsic flexibility and rigid domain motions in ligand binding. |
| 12411433 |
Data suggest that translocation of PTS1-containing proteins across the peroxisomal membrane occurs concomitantly with formation of the Pex5p-Pex14p membrane complex and that this is probably the site from which Pex5p leaves the peroxisomal compartment. |
| 16403517 |
Results indicate that the N-terminal half of Pex5p is best described as a natively unfolded pre-molten globule-like domain. |
| 15866874 |
Pex5p is a monomeric protein with an abnormal shape |
| 14652019 |
concluded that the PTS1 domain of SR-BI is functional and can mediate peroxisomal interaction via Pex5p, in vitro |
| 12578380 |
Binding energy threshold data have been generated for PTS1 pentapeptides containing different C-terminal tripeptide sequences to determine the functionality of specific PTS1 sequences. | →View more information from publications. |
Recent Publications on PEX5: |  |
Solution structure of human Pex5.Pex14.PTS1 protein complexes obtained by small angle X-ray scattering.
The Pex5p receptor recognizes newly synthesized peroxisomal matrix... | 3rd November, 2009
| European Molecular Biology Laboratory-Hamburg Outstation, c/o DESY,
| J Biol Chem. 2009 Sep 11;284(37):25334-42. Epub 2009 Jul 6.
DOI Direct Link |
Mapping the cargo protein membrane translocation step into the PEX5 cycling pathway.
Newly synthesized peroxisomal matrix proteins are targeted to the... | 22nd October, 2009
| Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto,
| J Biol Chem. 2009 Oct 2;284(40):27243-51. Epub 2009 Jul 23.
DOI Direct Link |
alpha-Synuclein abnormalities in mouse models of peroxisome biogenesis disorders.
alpha-Synuclein (alphaS) is a presynaptic protein implicated in... | 16th October, 2009
| Department of Biochemistry and Molecular Biology, The Institute for
| J Neurosci Res. 2009 Oct 14.
DOI Direct Link |
Pex2 and pex12 function as protein-ubiquitin ligases in peroxisomal protein import.
The PTS1-dependent peroxisomal matrix protein import is facilitated by the... | 19th August, 2009
| Institut fur Physiologische Chemie, Ruhr-Universitat Bochum,
| Mol Cell Biol. 2009 Oct;29(20):5505-16. Epub 2009 Aug 17.
DOI Direct Link |
Hitchhiking of Cu/Zn superoxide dismutase to peroxisomes--evidence for a natural piggyback import mechanism in mammals.
Most newly synthesized peroxisomal proteins are imported in a... | 19th August, 2009
| Department of Anatomy and Cell Biology, Ruprecht-Karl University, 69120
| Traffic. 2009 Nov;10(11):1711-21. Epub 2009 Jul 21.
DOI Direct Link |
→View more research publications. |
PEX5 results (if any) from reagent suppliers | 
|
Peroxin 5 (h): 293T Lysate sc-173622
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, PEX5, 5830, 12p13.31, P50542 ...
http://www.scbt.com/datasheet-173622-peroxin-5-h-293t-lysate...
|
 |
Other: TPR Domain
PEX5, PTS-1 target signal, S-K-L-COOH. Hop, Hsp70 - C-term heptapeptide. Hsp90 - C-term pentapeptide, E-E-V-D-COOH E-E-V-D-COOH ...
http://www.cellsignal.com/reference/domain/tpr.html...
|
 |
Peroxin 5 (G-20) Antibody sc-23190
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, PEX5, 5830, 12p13.31, NM_000319 ...
http://www.scbt.com/ja/datasheet-23190-peroxin-5-g-20-antibo...
|
 |
Gateway® Citations
receptor PEX5. Archives of Biochemistry and Biophysics, In Press,. Uncorrected Proof, Available online 7 October 2005 ...
http://www.invitrogen.com/etc/medialib/en/filelibrary/pdf.Pa...
|
 |
Peroxin 5 (V-20) Antibody sc-23188
Humano, PEX5, 5830, 12p13.31, NM_000319 · P50542 · 600414. Ratón, Pex5, 19305, 6 F2, O09012, No Aplicable. Información sobre pedidos ...
http://www.scbt.com/es/datasheet-23188-peroxin-5-v-20-antibo...
|
 |
Peroxin 5 (G-20) Antibody sc-23190
Humain, PEX5, 5830, 12p13.31, NM_000319 · P50542 · 600414. Souris, Pex5, 19305, 6 F2, O09012, Non disponible. Produits disponibles ...
http://www.scbt.com/fr/datasheet-23190-peroxin-5-g-20-antibo...
|
 |
Peroxin 5 (G-20) Antibody sc-23190
Spezies, Gen, Gen ID, Chromosomaler Locus, mRNA (Isoform) Accession #, Protein Accession #, OMIM™ Nummer. Human, PEX5, 5830, 12p13.31, NM_000319 · P50542 ...
http://www.scbt.com/de/datasheet-23190-peroxin-5-g-20-antibo...
|
 |
Search Bioportfolio and other Life Science Sites for PEX5,
or search for PEX5 on BioPortfolio's antibody search engine.
This page has been viewed 169 times
Recent Search Terms used to find this page: peroxisome biogenesis signaling | PEROXISOMAL BIOGENESIS FACTOR PEX5 | Peroxisomal biogenesis factor 5 isoform c Homo sapiens | factor 5 mutation | Entrez Gene PEX5 peroxisome biogenesis factor 5 Homo sapiens .htm | factor 5 mutation | peroxisomal biogenesis 2008 | factor 5 and glacoma | peroxisome biogenesis factor 5 | .
Resources from the NCBI used on this page, NCBI's standard disclaimer applies.
|
