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RAB3A


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Gene DB Home
Symbol:RAB3A
Name(s):RAB3A, member RAS oncogene family
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16584842 Observational study of gene-disease association. (HuGE Navigator)
17625073 Initiates exocytosis in acrosome when prenylated and activated with guanosine triphosphate (GTP).
12937130 a possible role in glomerulopathies
15005721 Mutation screening of the RAB3A gene in 47 individuals with autism provided no evidence that DNA variants in this gene are associated with autism.
16099449 Cholesterol content regulates acrosomal exocytosis by enhancing Rab3A plasma membrane association.
16584842 In conclusion, we have found no evidence for RAB3A conferring susceptibility on mental retardation in the Han Chinese population.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDRab geranylgeranyltransferase, component ARAB3A, member RAS oncogene family--Pubmed
HPRDchoroideremia isoform aRas associated protein Rab3A--Pubmed
HPRDChoroidermia likeRAB3A, member RAS oncogene family--Pubmed
HPRDchoroideremia-like Rab escort protein 2Ras associated protein Rab3A--Pubmed
HPRDRas associated protein Rab3ARab geranylgeranyltransferase, beta subunit--Pubmed
HPRDRas associated protein Rab3Arabphilin 3A-like--Pubmed
HPRDRas associated protein Rab3ARAB3A interacting protein-like 1--Pubmed
HPRDRas associated protein Rab3Aregulating synaptic membrane exocytosis 2--Pubmed
HPRDRas associated protein Rab3Arabphilin 3A homolog--Pubmed
HPRDRas associated protein Rab3ADmx-like 2--Pubmed

Recent Publications on RAB3A:

Pubmed Logo
Rab3a interacting molecule (RIM) and the tethering of presynaptic transmitter release site-associated CaV2.2 calcium channels.
Abstract Biochemical and physiological evidence suggest that presynaptic...
3rd November, 2009
Laboratory of Synaptic Transmission, Toronto Western Research Institute, J Neurochem. 2009 Oct 30.
DOI Direct Link
Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis.
Exocytosis of the acrosome (the acrosome reaction) relies on cAMP...
3rd November, 2009
Laboratorio de Biologia Celular y Molecular, Instituto de Histologia y J Biol Chem. 2009 Sep 11;284(37):24825-39. Epub 2009 Jun 22.
DOI Direct Link
Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation.
While serotonin (5-HT) co-localization with insulin in granules of...
28th October, 2009
Department of Human Molecular Genetics, Max Planck Institute for Molecular PLoS Biol. 2009 Oct;7(10):e1000229. Epub 2009 Oct 27.
DOI Direct Link
IA-2 modulates dopamine secretion in PC12 cells.
The secretion of the hormone insulin from beta cells is modulated by the...
6th October, 2009
Experimental Medicine Section, Oral Infection and Immunity Branch, Mol Cell Endocrinol. 2009 Sep 30.
DOI Direct Link
Podocyte glutamatergic signaling contributes to the function of the glomerular filtration barrier.
Podocytes possess the complete machinery for glutamatergic signaling,...
3rd October, 2009
Renal Research Laboratory, Fondazione IRCCS Ospedale Maggiore Policlinico, J Am Soc Nephrol. 2009 Sep;20(9):1929-40. Epub 2009 Jul 2.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
5981226 Vesicle transport associated proteins
6660846 Vesicular amino acid transporter composition and method
6706867 DNA array sequence selection
6773920 Delivery of functional protein sequences by translocating polypeptides
6790949 Protein Rim2

View more patents.

RAB3A results (if any) from reagent suppliers

Google CSE Logo
Rab3A antibody (ab3335) | Abcam
Rabbit polyclonal to Rab3A. Rab3A is a 25kD GTP-binding protein implicated in neurotransmitter release. The geranylgeranyl groups at the carboxyl-terminus ...
http://www.abcam.com/Rab3A-antibody-ab3335.html...

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Anti-RAB3A Polyclonal Antibody
Polyclonal Antibody against RAB3A for use in Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

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Rab3A Antibody
ing Rab3A-3D, are involved in the exocytosis of neurotrans- mitters and hormones (1). ... molecular switch between active, GTP-bound Rab3A and the ...
http://www.cellsignal.com/pdf/3930.pdf...

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Rab 3
Biochemical, molecular and behavioral phenotypes of Rab3A mutations in the ... Glomerular podocytes possess the synaptic vesicle molecule Rab3A and its ...
http://www.sysy.com/products/rab3/ref.php...

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Anti-VAMP2 Polyclonal Antibody
RAB3A Antibody (PA1-770). RAB3C Antibody (PA1-772). Rabphilin 3A Antibody (PA1- 774). Rat VAMP-2 (residues 1-18) Peptide (PEP-101) ...
http://www.bioreagents.com/products/printProductDetail/print...

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Rab 3A (K-15) Antibody sc-308
Insulin secretory deficiency and glucose intolerance in Rab3A null mice. J. Biol . Chem. 278: 9715-9721. View PubMed Entry ...
http://www.scbt.com/datasheet-308-rab-3a-k-15-antibody.html...

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Q-R
HPA003160, Anti-RAB3A antibody produced in rabbit, affinity isolated antibody, human ... RAB3A(5864), human, IHC (p), PA, pricing ...
https://www.sigmaaldrich.com/etc/controller/controller-page....

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