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RAB6A
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17573808 |
a highly significant correlation between the Rab6 and the UPR marker BiP in Alzheimer disease brains. |
| 17699596 |
Rab6 regulates distinct Golgi trafficking pathways involving two separate protein complexes: ZW10/RINT-1 and COG. |
| 17716866 |
These data demonstrate that Rab2 and Rab6 differentially influence anterograde transport and signaling of GPCRs. |
| 17681140 |
These data demonstrate that although Rab6 is not essential for secretion, it controls the organization of exocytosis within the cellular space. |
| 16332443 |
Results show the crystal structure of the GTPase Rab6A in the GTP bound form. |
| 12738866 |
recombinant antibodies specific to the GTP-bound conformation of Rab6 were generated and used to locate Rab6; Rab6 was in its GTP-bound conformation on the Golgi apparatus and transport intermediates |
| 16536738 |
Results show that Rab6A and Rab6A' perform different functions within the cell and suggests a novel role for Rab6A' as the major Rab6 isoform regulating previously described Rab6-dependent transport pathways. |
| 15483056 |
Rab6A and Rab6A' regulate microtubule-dependent recycling at the trans-Golgi network |
| 16395330 |
Rab6A' likely regulates the dynamics of the dynein/dynactin complex at the kinetochores and consequently the inactivation of the Mad2-spindle checkpoint. |
| 16683916 |
role of the Rab6 isoforms in retrograde transport of ricin using both oligo- and vector-based RNAi assays | →View more information from publications. |
Recent Publications on RAB6A: |  |
The localization of the Golgin GCC185 is independent of Rab6A/A' and Arl1.
Mammalian golgins of the trans-Golgi network (TGN) are small G protein... | 24th September, 2009
| The Department of Biochemistry and Molecular Biology, The University of
| Cell. 2009 Aug 21;138(4):787-94.
DOI Direct Link |
Structural aspects of Rab6-effector complexes.
The small GTPase Rab6 regulates vesicle trafficking at the level of Golgi.... | 17th September, 2009
| School of Biochemistry and Immunology, Trinity College, Dublin 2, Ireland.
| Biochem Soc Trans. 2009 Oct;37(Pt 5):1037-41.
DOI Direct Link |
Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.
The Tre-2/Bub2/Cdc16 (TBC) domain is a conserved protein motif that... | 11th April, 2009
| Laboratory of Membrane Trafficking Mechanisms, Department of Developmental
| Genes Cells. 2009 Jan;14(1):41-52. Epub 2008 Dec 10.
DOI Direct Link |
Biophysical analysis of the interaction of Rab6a GTPase with its effector domains.
Rab GTPases are key regulators of intracellular vesicular transport that... | 8th April, 2009
| Department of Physical Biochemistry, Max Planck Institute for Molecular
| J Biol Chem. 2009 Jan 30;284(5):2628-35. Epub 2008 Nov 19.
DOI Direct Link |
Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain.
Small GTPase Rab6 regulates vesicle trafficking at the level of Golgi via... | 7th March, 2009
| School of Biochemistry and Immunology, Trinity College, Dublin 2, Ireland.
| Structure. 2009 Jan 14;17(1):21-30.
DOI Direct Link |
→View more research publications. |
RAB6A results (if any) from reagent suppliers | 
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RAB6A antibodies: Signal Transduction > Protein Trafficking ...
RAB6A antibodies. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab55660 · RAB6A antibody. IHC-P, WB ...
http://www.abcam.com/index.html?t=227573&pt=1&c=2249&ei=&mu=...
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Rab 6 (C-19) Antibody sc-310
Regulation of microtubule-dependent recycling at the trans-golgi network by Rab6A and Rab6A'. Mol Biol Cell. 16: 162-177. View PubMed Entry ...
http://www.scbt.com/datasheet-310-rab-6-c-19-antibody.html...
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Current References on RNAi
A role for the Rab6A' GTPase in the inactivation of the Mad2-spindle checkpoint. Miserey-Lenkei, S., et al., EMBO J. 2006.25: 278-89. abstract ...
https://www.sigmaaldrich.com/life-science/functional-genomic...
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BUBR1 (C-20) Antibody sc-16195
A role for the Rab6A' GTPase in the inactivation of the Mad2-spindle checkpoint. EMBO J. 25: 278-289. View PubMed Entry. Oikawa T et al. 2005. ...
http://www.scbt.com/datasheet-16195-bubr1-c-20-antibody.html...
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Abcam antibodies and reagents product map
... RAB38 antibodies (3) · RAB39 antibodies (1) · RAB3GAP1 antibodies (1) · RAB40B antibodies (2) · RAB5C antibodies (1) · RAB6A antibodies (1) ...
http://www.abcam.com/index.html?c=2105...
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Rab 6 (FL-208) Antibody sc-28571
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, RAB6A, 5870, 11q13.4, NM_002869, ...
http://www.scbt.com/datasheet-28571-rab-6-fl-208-antibody.ht...
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< 다음 5 논문 >
Human, RAB6A, 5870, 11q13.4, NM_002869, NM_198896 · P20340 ... Regulation of microtubule-dependent recycling at the trans-golgi network by Rab6A and Rab6A'.
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http://www.scbt.com/ko/product.php?datasheet=310&page=2&tota...
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