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RAB27A
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18311812 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17352418 |
The present results provide evidence from live retinal pigment epithelium cells that the RAB27A-MYRIP-MYO7A complex functions in melanosome motility. |
| 16762324 |
findings show that Rab27a is involved in CFTR channel regulation through protein-protein interactions involving Munc13-4 and SLP-5 effector proteins |
| 17255357 |
A novel homozygous mutation in the RAB27A gene of a new Griscelli syndrome patient. |
| 16923811 |
EPI64 is a GTPase-activating protein specific for Rab27A |
| 11980908 |
role in melanosome transport |
| 12446441 |
Rab27a mutations occurring in Griscelli syndrome patients reveal structure-activity relationships affecting GTP & GDP binding, melanophilin binding, melanosome distribution, and cytotoxic granule exocytosis. |
| 12122117 |
Rab27b is functionally redundant with Rab27a and the pathogenesis of Griscelli syndrome is determined by the relative expression of Rab27a and Rab27b in specialized cell types. |
| 12058346 |
Griscelli syndrome with neurological involvement is caused by mutations in RAB27A |
| 16630545 |
These observations decisively prove that Rab27a inhibits ENaC function through a complex mechanism that involves GTP/GDP status, and protein-protein interactions involving Munc13-4 and SLP-5 effector proteins. | →View more information from publications. |
Recent Publications on RAB27A: |  |
Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation.
While serotonin (5-HT) co-localization with insulin in granules of... | 28th October, 2009
| Department of Human Molecular Genetics, Max Planck Institute for Molecular
| PLoS Biol. 2009 Oct;7(10):e1000229. Epub 2009 Oct 27.
DOI Direct Link |
[Formation and function of Weibel-Palade bodies]
Weibel-Palade bodies (WPB) are specialized cigar-shaped secretory... | 13th October, 2009
| Institute of Genetics and Developmental Biology, Chinese Academy of
| Yi Chuan. 2009 Sep;31(9):882-8.
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Griscelli syndrome type 2: long-term follow-up after unrelated donor bone marrow transplantation.
Griscelli syndrome (GS) is a rare autosomal recessive disease... | 3rd October, 2009
| Department of Dermatology, La Sapienza University, Rome, Italy.
| Dermatology. 2009;218(4):376-9. Epub 2009 Mar 6.
DOI Direct Link |
Follicular lymphoma cells induce T-cell immunological synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy.
An important hallmark of cancer progression is the ability of tumor cells... | 30th September, 2009
| Institute of Cancer, Cancer Research UK Clinical Centre for Medical
| Blood. 2009 Sep 28.
DOI Direct Link |
Hematopoietic- and neurologic-expressed sequence 1 (Hn1) depletion in B16.F10 melanoma cells promotes a differentiated phenotype that includes increased melanogenesis and cell cycle arrest.
The Hematopoietic- and neurologic-expressed sequence 1 (Hn1) gene encodes... | 11th September, 2009
| Departments of Pharmacology & Therapeutics, University of Florida, College
| Differentiation. 2009 Jul;78(1):35-44. Epub 2009 May 7.
DOI Direct Link |
→View more research publications. |
RAB27A results (if any) from reagent suppliers | 
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RAB27A antibody (ab55667) | Abcam
Mouse monoclonal to RAB27A. The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be
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http://www.abcam.com/RAB27A-antibody-ab55667.html...
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Q-R
HPA001333, Anti-RAB27A antibody produced in rabbit, affinity isolated antibody, human ... RAB27A(5873), human, IHC (p), PA, WB, pricing ...
https://www.sigmaaldrich.com/etc/controller/controller-page....
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RAB27A antibodies: Signal Transduction > Signaling Pathway > G ...
RAB27A antibodies. ... RAB27A antibody. IHC-P, WB, ICC/IF, IP. Images · Customer Abreviews: 3 stars (out of 5). Mouse monoclonal ...
http://www.abcam.com/index.html?t=227578&pt=1&c=2163&ei=&mu=...
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Rab 27a (E-8) Antibody sc-74586
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, RAB27A, 5873, 15q21.3, P51159 ...
http://www.scbt.com/datasheet-74586-rab-27a-e-8-antibody.htm...
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Myosin Va Antibody
nophilin and Rab27a (5). Myosin Va regulates trafficking and exocytosis of secretory granules in neuroendocrine cells (reviewed in 6) as well as RNA ...
http://www.cellsignal.com/pdf/3402.pdf...
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Rab 27a (C-20) Antibody sc-22990
Human, RAB27A, 5873, 15q21.3, NM_004580, NM_183234, NM_183235, NM_183236 · P51159 · 607624. Mouse, Rab27a, 11891, 9 D, Q9ERI2 ...
http://www.scbt.com/datasheet-22990-rab-27a-c-20-antibody.ht...
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A9309 Anti-Mouse IgG (Fc specific)–Peroxidase antibody produced in ...
Wang, F., et al., Rab27a Is an Essential Component of Melanosome Receptor for Myosin Va Mol. Biol. Cell 13, 1735-1749, (2002) Abstract ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=A930...
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