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RAD9A


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Symbol:RAD9A
Name(s):RAD9 homolog A (S. pombe)
Type:protein-coding
Organism:Homo sapiens
Synonyms:RAD9
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18156970 Rad9 expression correlated closely to significance only with the apoptotic and mitotic indices in epithelial ovarian tumors
17511890 Rad9 modulates the P21WAF1 pathway by direct association with p53.
17493829 we report successful tri-cistronic cloning, overexpression and purification of a three-protein complex of Rad9, Rad1 and Hus1 using a single hexa-histidine tag.
12941802 hRad9/hHus1/hRad1 complex acts as a checkpoint sensor during S phase by rapidly localizing to sites of DNA damage and transducing checkpoint responses by facilitating proper localization of downstream checkpoint proteins, including TopBP1.
15326225 Rad9 stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CAD.
16365875 The encoded mammalian proteins participate in promoting resistance to DNA damage, cell cycle checkpoint control, DNA repair, and apoptosis.
11994305 role of C-terminal region in nuclear transport of the hRad9 checkpoint complex
15773892 Rad9 plays critical role in the activation of S-phase checkpoint and the maintenance of chromosome stability.
15871698 The long-patch base excision machinery is an important target of the Rad9-Rad1-Hus1 complex, thus enhancing the quality control of DNA.
14966297 Data report the identification of Rad9, a key member of the checkpoint Rad protein family, as a coregulator to suppress androgen-androgen receptor transactivation in prostate cancer cells.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDABLRAD9 homolog--Pubmed
HPRDv-abl Abelson murine leukemia viral oncogene homolog 1 isoform aRAD9--Pubmed
HPRDB-cell lymphoma protein 2 alpha isoformRAD9 homolog--Pubmed
HPRDB-cell lymphoma protein 2 alpha isoformRAD9 homolog--Pubmed
HPRDHistone deacetylase 1RAD9 homolog--Pubmed
HPRDhistone deacetylase 1RAD9--Pubmed
HPRDHUS1 checkpoint proteinRAD9 homolog--Pubmed
HPRDHUS1 checkpoint proteinRAD9 homolog--Pubmed
BINDHUS1 checkpoint proteinRAD9 homologRad9 interacts with Hus1.-Pubmed
BINDHUS1 checkpoint proteinRAD9 homologRad9 interacts with Hus1.-Pubmed

Recent Publications on RAD9A:

Pubmed Logo
Human cell toxicogenomic analysis of bromoacetic acid: A regulated drinking water disinfection by-product.
The disinfection of drinking water is a major achievement in protecting...
16th September, 2009
College of Agricultural, Consumer and Environmental Sciences, Department Environ Mol Mutagen. 2009 Sep 14.
DOI Direct Link
A 7 Mb region within 11q13 may contain a high penetrance gene for breast cancer.
Familial breast cancer represents up to 5% of all breast cancer cases....
12th February, 2009
Human Genetics Group, Human Cancer Genetics Programme, Spanish National Breast Cancer Res Treat. 2009 Nov;118(1):151-9. Epub 2009 Feb 10.
DOI Direct Link
Haplotype-based analysis of genes associated with risk of adverse skin reactions after radiotherapy in breast cancer patients.
PURPOSE: To identify haplotypes of single nucleotide polymorphism markers...
6th December, 2007
RadGenomics Project, National Institute of Radiological Sciences, Chiba, Int J Radiat Oncol Biol Phys. 2007 Nov 1;69(3):685-93.
DOI Direct Link
Identification of differentially expressed genes contributing to radioresistance in lung cancer cells using microarray analysis.
Radiotherapy has played a key role in the control of tumor growth in many...
24th August, 2005
Beijing Institute of Radiation Medicine, Beijing 100850, China. Radiat Res. 2005 Jul;164(1):27-35.

RAD9A results (if any) from reagent suppliers

Google CSE Logo
Q-R
HPA006725, Anti-RAD9A antibody produced in rabbit, affinity isolated antibody, human ... RAD9A(5883), human, IHC (p), PA, pricing ...
https://www.sigmaaldrich.com/etc/controller/controller-page....

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Phospho-Rad9-S272 Antibody
Cell cycle checkpoint control protein; RAD9 homolog A; S. pombe; RAD9A;. Application Data: Calculated MW: 42547 Da. Phospho-Rad9-S272 Antibody ...
http://www.abgent.com/products/catalog_no/AP3223a_Phospho_Ra...

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p-Rad9 (Ser 277) Antibody sc-130213
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, RAD9A, 5883, 11q13.1, Q99638 ...
http://www.scbt.com/datasheet-130213-p-rad9-ser-277-antibody...

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Rad9 antibody (ab50311) | Abcam
The immunizing peptide corresponds to RAD9A and is not present in RAD9B. BLAST ' PQGPSPVLAEDSEGEG' with BLAST the sequence with ExPASy ...
http://www.abcam.com/Rad9-antibody-ab50311.html...

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Antibodies to DNA Repair Proteins
RAD9A(5883), human, WB, pricing. S7822, Anti-SMC6 antibody produced in rabbit, IgG fraction of antiserum, rat ... Smc6l1(313961) mouse ... Smc6(67241) ...
https://www.sigmaaldrich.com/etc/controller/controller-page....

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Antibodies to Check Point Proteins
RAD9A(5883), human, WB, pricing. S6446, Anti-SMC1L1 (C-terminal) antibody produced in rabbit, (polyclonal), IgG fraction of antiserum, rat ... Smc1a(63996
) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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Phospho-Rad9-Y28 Antibody Blocking Peptide
Cell cycle checkpoint control protein; RAD9 homolog A; S. pombe; RAD9A;. Application Data: Calculated MW: 1728.23 Da ...
http://www.abgent.com/products/catalog_no/BP3231a_Phospho_Ra...

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