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RAD51L3


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Symbol:RAD51L3
Name(s):RAD51-like 3 (S. cerevisiae)
Type:protein-coding
Organism:Homo sapiens
Synonyms:HsTRAD, R51H3, RAD51D, Trad
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15170666 Observational study of gene-disease association. (HuGE Navigator)
18058226 Observational study of gene-disease association. (HuGE Navigator)
15109494 Telomere maintenance requires RAD51D.
12975363 RAD51L3 cooperates with Bloom Syndrome Protein during the late stages of homologous recombination processes that serve to restore productive DNA replication at sites of damaged or stalled replication forks
16717288 Interactions between RAD51D and its XRCC2 and RAD51C partners require a functional RAD51D Walker B ATPase motif, but not motif A.
15170666 E233G single nucleotide polymorphism is a low-penetrance susceptibility gene in the specific subgroup of high-risk familial breast cancer cases that are not related to BRCA1/2.
11834724 Homologous pairing and ring and filament structure formation activities of the human Xrcc2*Rad51D complex

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDBLMRAD51-like 3 isoform 1--Pubmed
HPRDRecQ protein like 3RAD51-like 3 isoform 1--Pubmed
HPRDBloom syndrome proteinDNA repair protein RAD51 homolog 4--Pubmed
HPRDRAD51 homolog C isoform 1DNA repair protein RAD51 homolog 4--Pubmed
HPRDRAD51 homolog C isoform 1RAD51-like 3 isoform 1--Pubmed
HPRDRAD51-like 1 isoform 3DNA repair protein RAD51 homolog 4--Pubmed
HPRDRAD51-like 1 isoform 3RAD51-like 3 isoform 1--Pubmed
HPRDDNA repair protein RAD51 homolog 4X-ray repair cross complementing protein 2--Pubmed
HPRDDNA repair protein RAD51 homolog 4X-ray repair cross complementing protein 3--Pubmed
HPRDRAD51-like 3 isoform 1XRCC3--Pubmed

Recent Publications on RAD51L3:

Pubmed Logo
The interaction profile of homologous recombination repair proteins RAD51C, RAD51D and XRCC2 as determined by proteomic analysis.
The RAD51 family of proteins is involved in homologous recombination (HR)...
30th October, 2009
Department of Pharmaceutical and Biomedical Sciences, South Carolina Proteomics. 2009 Aug;9(16):4071-86.
DOI Direct Link
Cisplatin resistance conferred by the RAD51D (E233G) genetic variant is dependent upon p53 status in human breast carcinoma cell lines.
RAD51D, a paralog of the mammalian RAD51 gene, contributes towards...
27th June, 2009
Department of Biochemistry and Cancer Biology, University of Toledo Mol Carcinog. 2009 Jul;48(7):586-91.
DOI Direct Link
Functional characterization and identification of mouse Rad51d splice variants.
BACKGROUND: The homologous recombination (HR) pathway is vital for...
23rd May, 2009
Department of Pharmaceutical and Biomedical Sciences, South Carolina BMC Mol Biol. 2009 Mar 27;10:27.
DOI Direct Link
Functional characterization of the RAD51D E233G genetic variant.
BACKGROUND AND OBJECTIVE: RAD51D, a paralog of the mammalian RAD51 gene,...
8th April, 2009
Department of Biochemistry and Cancer Biology, University of Toledo Pharmacogenet Genomics. 2009 Feb;19(2):153-60.
DOI Direct Link
The RAD51D E233G variant and breast cancer risk: population-based and clinic-based family studies of Australian women.
RAD51D is a homolog of the RAD51 protein, which is known to be an...
17th December, 2008
Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, Breast Cancer Res Treat. 2008 Nov;112(1):35-9. Epub 2007 Dec 4.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7604936 Methods and compositions for diagnosis and monitoring auto immune and chronic inflammatory diseases
7470688 Phthalazinone derivatives
7449464 Phthalazinone derivatives
7407957 Phthalazinone derivatives
7279463 Triple-helix forming oligonucleotides for targeted mutagenesis

View more patents.

RAD51L3 results (if any) from reagent suppliers

Google CSE Logo
Antibody Products - Protein and Antibody Solutions Provider - GenWay
Mouse monoclonal [Rad51D 5A8 / 4] to Rad51D; 5892; RAD51L3; 602954; O75771; HsTRAD; R51H3; RAD51D; Trad;; DNA repair protein RAD51 homolog 4, IgG Monoclonal
...
http://www.genwaybio.com/all_monoclonal_antibodies.php?fl=R...

Thumbshot
Rad51D (5B3/6) Antibody sc-53432
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, RAD51L3, 5892, 17q12, NM_002878, ...
http://www.scbt.com/datasheet-53432-rad51d-5b3-6-antibody.ht...

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Antibodies available - Antibodies | Imgenex
IMX-3114, RAD51D / TRAD, TRAD, RAD51L3, R51H3, HsTRAD, Purified, Peptide Affinity, H, N/A, Peptide ELISA*, 0.1 mg, N/A, View MSDS ...
http://www.imgenex.com/alphabetic_antibody_list.php?key=R&do...

Thumbshot
Rad51D (h): 293T Lysate sc-175080
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, RAD51L3, 5892, 17q12, O75771 ...
http://www.scbt.com/datasheet-175080-rad51d-h-293t-lysate.ht...

Thumbshot
Rad51D (S-15) Antibody sc-33089
Humano, RAD51L3, 5892, 17q12, NM_002878, NM_133629 · O75771 · 602954. Ratón, Rad51l3, 19364, 11 C, O55230, No Aplicable ...
http://www.scbt.com/es/datasheet-33089-rad51d-s-15-antibody....

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Rad51D (C-16) Antibody sc-33090
Humain, RAD51L3, 5892, 17q12, NM_002878, NM_133629 · O75771 · 602954. Souris, Rad51l3, 19364, 11 C, O55230, Non disponible ...
http://www.scbt.com/fr/datasheet-33090-rad51d-c-16-antibody....

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