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BCL2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17912028 |
This study aimed to explore, whether polymorphisms in BCL2, Cyclin D1, FAS, EGF and EGFR genes affect survival in a cohort of patients with squamous cell esophageal cancer treated with CT+RT with a view to identify the potential therapeutic targets. |
| 18023359 |
IL-10 modulated the pro-apoptotic capacity of TNF-alpha in chondrocytes as shown by the decrease in caspase activities and bax/bcl-2 ratio |
| 18182854 |
substitution of C-terminal tail or tail & adjacent loop of Bcl-2 with equivalent regions from Bak or Bax mutant resulted in association with mitochondria. change in subcellular localization of Bcl-2 chimeras triggered cells to undergo apoptotis |
| 18046447 |
our data do not support the use of the (-938C>A) BCL-2 polymorphism as a prognostic marker in CLL and argue against its postulated role in modulating Bcl-2 levels. |
| 18046449 |
GCs induce both pro- and anti-apoptotic BCL2 family member-dependent pathways, with the outcome depending on cellular context and additional signals feeding into the BCL2 rheostat. |
| 16215670 |
These findings imply that some of the biological functions of Bcl-2 may be attributed to their ability to inhibit anticancer agents-induced apoptosis through the sustained Akt activation. |
| 18334006 |
this study has found bcl-2 of no value as a prognostic marker in this group of serous ovarian tumors |
| 18162459 |
In thyroid glands of patients with Graves disease the regulation of Fas/Fas ligand/Bcl-2 favors apoptosis of infiltrating lymphocytes. |
| 17693666 |
Risk for head and neck squamous cell carcinoma may be assocated with single-nucleotide polymorphism in the promoter region. |
| 17959858 |
BCL2 protein levels in CLL reflect a complex interplay of transcriptional and posttranscriptional controls, but do not appear to be associated with the -938C>A promoter SNP. | →View more information from publications. |
Recent Publications on BCL2: |  |
Repeated cocaine administration increases B-cell leukemia/lymphoma 2 phosphorylation in the rat dorsal striatum.
Protein phosphorylation caused by drug administration is a critical step... | 3rd November, 2009
| Department of Biological Sciences, Pusan National University, 30
| Neurosci Lett. 2009 Oct 29.
DOI Direct Link |
EM011 activates a survivin-dependent apoptotic program in human non-small cell lung cancer cells.
ABSTRACT: BACKGROUND: Lung cancer remains a leading cause of cancer death... | 3rd November, 2009
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| Mol Cancer. 2009 Oct 30;8(1):93.
DOI Direct Link |
Poor outcome in patients with diffuse large B-cell lymphoma is associated with high percentage of bcl-2 and Ki 67-positive tumor cells.
BACKGROUND/AIM: Newly diagnosed patients with diffuse large B-cell... | 3rd November, 2009
| Clinical Center of Serbia, Institute of Hematology, Belgrade, Serbia.
| Vojnosanit Pregl. 2009 Sep;66(9):738-43.
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CCL2 is induced by chemotherapy and protects prostate cancer cells from docetaxel-induced cytotoxicity.
BACKGROUND: Metastatic prostate cancer is either inherently resistant to... | 30th October, 2009
| Division of Hematology and Medical Oncology, Oregon Health & Science
| Prostate. 2009 Oct 28.
DOI Direct Link |
A coumarin derivative (RKS262) inhibits cell-cycle progression, causes pro-apoptotic signaling and cytotoxicity in ovarian cancer cells.
Coumarin derivative RKS262 belongs to a new class of potential anti-tumor... | 30th October, 2009
| Molecular Therapeutics Laboratory, Program in Women's Oncology, Department
| Invest New Drugs. 2009 Oct 29.
DOI Direct Link |
→View more research publications. |
Press Releases on BCL2:
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| Clarient Launches New Breast Cancer Test |
5th May, 2009 |
Clarient, Inc. |
The Clarient Insight(R) Dx Breast Cancer Profile Assists Physicians In Identifying Recurrence Risk and the Need for Chemotherapy
ALISO VIEJO, Calif., May 5 /PRNewswire
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BCL2 results (if any) from reagent suppliers | 
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