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BACH2


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Symbol:BACH2
Name(s):BTB and CNC homology 1, basic leucine zipper transcription factor 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17991429 This study demonstrates a novel role for Bach2 as a key regulator of nucleic acid-triggered antiviral responses in human cells.
14982850 loss of BACH2 expression through Epstein-Barr virus integration might contribute to lymphomagenesis
16832351 Upregulation of BACH2 is associated with ovarian cancer
17044046 down-regulation of the BACH2 gene through the interaction with centromeric heterochromatin would take part in leukomogenesis of BCR-ABL positive lymphoid leukemia.
17262715 This study demonstrated strong integration clusters in the BACH2 gene were observed in 2 HIV infection patients without detectable viremia.
17383980 expression of the silencing mediator of retinoid and thyroid receptor (SMRT) & histone deacetylase4 (HDAC4) enhances formation of Bach2 foci in nuclear matrix. SMRT mediates HDAC4 binding to Bach2, & HDAC4 facilitates the retention of Bach2 in the foci.
11746976 BACH2 is transcriptionally regulated by the BCR/ABL oncogene.
12829606 antineoplastic drugs that were oxidative stressors induced the nuclear accumulation of BACH2
15060166 Results demonstrate that transcription activity associated with PML bodies is selectively repressed by the recruitment of Bach2 around PML bodies.
17018862 Bach2 is phosphorylated on S521 via Bcr-Abl signaling thru the phosphatidylinositol-3/S6 kinase pathway,and transcriptionally represses heme oxygenase-1

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDMAFKBTB and CNC homology 1, basic leucine zipper transcription factor 2--Pubmed

Press Releases on BACH2:

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Researchers Continue to Find Genes for Type 1 Diabetes 14th October, 2008 The Children's Hospital of Philadelphia

PHILADELPHIA, Oct. 14 /PRNewswire-USNewswire/ -- Genetics researchers have identified two novel gene locations that raise the risk of type 1 diabetes. As they continue to

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
7235358 Methods and compositions for diagnosing and monitoring transplant rejection
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
6706867 DNA array sequence selection

View more patents.

BACH2 results (if any) from reagent suppliers

Google CSE Logo
BACH2 (L-17) Antibody sc-14704
See how others have used BACH2 (L-17): sc-14704 antibody and or BACH2 ... Bach2 is involved in neuronal differentiation of N1E-115 neuroblastoma cells. ...
http://www.scbt.com/datasheet-14704-bach2-l-17-antibody.html...

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All Oxidative Stress | Abcam
BACH2 antibody. WB, ELISA. Images. Rabbit polyclonal. Reacts with: Hu. ab77560 · BDH2 antibody. WB, ELISA. Images. Goat polyclonal. Reacts with: ...
http://www.abcam.com/index.html?c=3642...

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BACH2 (E-16) Antibody sc-14702
BACH2 (E-16): sc-14702 antibody 및 BACH2 (E-16) antibody conjugates를 사용한 논문 ... Identification of novel Bach2 transcripts and protein isoforms through
...
http://www.scbt.com/ko/datasheet-14702-bach2-e-16-antibody.h...

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Abcam antibodies and reagents product map
... B Cell antibodies (3) · B Cell Subset antibodies (2) · BACH2 antibodies (1) · BAFF antibodies (9) · BAFF proteins and peptides (8) · BAP29 antibodies (3 ...
http://www.abcam.com/index.html?pageconfig=productmap&cl=249...

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BACH Antibody / BACH Antibodies
BACH2 (E-16) Antibody, sc-14702, goat IgG, N-terminus (m), WB, IF, ELISA, m, r, h. BACH2 (L-17) Antibody, sc-14704, goat IgG, internal (m), WB, IF, ELISA ...
http://www.scbt.com/ko/table-bach.html...

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Cell Biology: primary antibodies, proteins, peptides, kits | Abcam
... ATOX1 proteins and peptides (1) · Ascorbic acid kits (2) · BACH2 antibodies (1) · BDH2 antibodies (2) · Biliverdin Reductase antibodies (3) ...
http://www.abcam.com/index.html?cl=246&pageconfig=productmap...

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BACH2 siRNA (h) sc-37706
Click here for details. suitable control antibody: BACH2 (L-17): sc-14704; sqRT- PCR Primer also available: BACH2 (h)-PR: sc-37706-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-37706-bach2-sirna-h.html...

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