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RRAS


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Gene DB Home
Symbol:RRAS
Name(s):related RAS viral (r-ras) oncogene homolog
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17664272 Notch1 ligand, Delta-like ligand-4, stimulates R-Ras-dependent alpha 5 beta 1 integrin-mediated adhesion, demonstrating the physiological relevance of this pathway.
12890755 activation of R-Ras promotes the formation of focal adhesions and a spread cell shape
15297673 Plexin-B1 mediates Sema4D-induced repulsive axon guidance signaling by acting as a GTPase activating protein for R-Ras
15525681 R-Ras plays a key role in cell migration by locally regulating the switch from Rac to Rho activity after membrane protrusion and adhesion
16914723 These findings show that R-Ras activity mediates inhibition of insulin signaling associated with suppression of estrogen action, implicating this GTPase in a growth-inhibitory mechanism associated with antiestrogen treatment of breast cancer.
12386818 study of the potential contribution in generating of estrogen-independence in MCF-7 cells
12548599 the oncogene R-Ras promotes tumor growth of cervical epithelial cells and increases their migration potential over collagen through a pathway that involves PI 3-K.
12529399 R-Ras promotes focal adhesion formation by signaling to FAK and p130(Cas) through a novel mechanism that differs from but synergizes with the alpha2beta1 integrin.
16754664 GPCRs rapidly activate R-Ras; R-Ras activation by the GPCRs is apparently directly induced by cyclic AMP-regulated Epac proteins; and activated R-Ras specifically controls GPCR-mediated phospholipase D stimulation
17107957 R-Ras and ILK have roles upstream of GSK-3beta in the regulation of neuronal polarity

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDARAF1related RAS viral oncogene homolog--Pubmed
HPRDv-raf murine sarcoma 3611 viral oncogene homologRas related protein--Pubmed
HPRDB-cell lymphoma protein 2 alpha isoformrelated RAS viral oncogene homolog--Pubmed
HPRDB-cell lymphoma protein 2 alpha isoformrelated RAS viral oncogene homolog--Pubmed
HPRDAF6related RAS viral oncogene homolog--Pubmed
HPRDmyeloid/lymphoid or mixed-lineage leukemiaRas related protein--Pubmed
HPRDNCK adaptor protein 1related RAS viral oncogene homolog--Pubmed
HPRDNCK adaptor protein 1related RAS viral oncogene homolog--Pubmed
HPRDral guanine nucleotide dissociation stimulator isoform 1related RAS viral oncogene homolog--Pubmed
HPRDral guanine nucleotide dissociation stimulator isoform 1related RAS viral oncogene homolog--Pubmed

Recent Publications on RRAS:

Pubmed Logo
Use of rasH2 transgenic mice for carcinogenesis testing of medical implants.
Several transgenic mice models are accepted by regulatory agencies to...
29th October, 2009
BIOMATECH-NAMSA, 115 rue Pasteur, Zi de L'Islon, Chasse sur Rhone, France. Exp Toxicol Pathol. 2009 Sep;61(5):433-41. Epub 2008 Dec 4.
DOI Direct Link
Snf1 controls the activity of adr1 through dephosphorylation of Ser230.
The transcription factors Adr1 and Cat8 act in concert to regulate the...
26th September, 2009
Department of Biochemistry, University of Washington, Seattle, Washington Genetics. 2009 Jul;182(3):735-45. Epub 2009 Apr 27.
DOI Direct Link
Sorting out RTs and RRAs.
The transcription factors Adr1 and Cat8 act in concert to regulate the...
20th May, 2009
Nursing. 2009 Mar;39(3):8.
DOI Direct Link
Different requirement for Rnd GTPases of R-Ras GAP activity of Plexin-C1 and Plexin-D1.
Plexins, comprising Plexin-A, -B, -C, and -D subfamilies, are receptors...
5th May, 2009
Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto J Biol Chem. 2009 Mar 13;284(11):6743-51. Epub 2009 Jan 9.
DOI Direct Link
M-Ras evolved independently of R-Ras and its neural function is conserved between mammalian and ascidian, which lacks classical Ras.
The Ras family small GTPases play a variety of essential roles in...
3rd March, 2009
Department of Biology, Graduate School of Science, Chiba University, 1-33 Gene. 2009 Jan 15;429(1-2):49-58. Epub 2008 Oct 11.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
6950930 Multistandard video decoder and decompression system for processing encoded bit streams including pipeline processing and methods relating thereto
7107326 Method and system for integrating IP address reservations with policy provisioning
7107347 Method and apparatus for network deception/emulation
7136312 Semiconductor device having read and write operations corresponding to read and write row control signals
7139208 Refresh-free dynamic semiconductor memory device

View more patents.

RRAS results (if any) from reagent suppliers

Google CSE Logo
RRAS antibody (ab47536) | Abcam
Rabbit polyclonal to RRAS. RRAS (Related RAS viral (r-ras) oncogene homolog) is a member of the Ras superfamily of small GTPases which regulate cell ...
http://www.abcam.com/RRAS-antibody-ab47536.html...

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R-Ras (C-19) Antibody sc-523
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, RRAS, 6237, 19q13.33, NM_006270 ...
http://www.scbt.com/datasheet-523-r-ras-c-19-antibody.html...

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RRAS antibodies: Cell Biology > Apoptosis > Intracellular ...
RRAS antibodies. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab47536 · RRAS antibody. IHC-P, WB, IP. Rabbit polyclonal
...
http://www.abcam.com/index.html?t=162780&pt=1&c=298&ei=&mu=r...

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Panorama® Antibody Array - Signal Transduction
RRAS. related RAS viral (r-ras) oncogene homolog. 6237 · RRAS2. related RAS viral (r-ras) oncogene homolog 2. 22800 · SAV1. salvador homolog 1 ...
http://www.sigmaaldrich.com/life-science/cell-biology/protei...

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R-Ras (C-19) Antibody sc-523
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, RRAS, 6237, 19q13.33, NM_006270 ...
http://www.scbt.com/ja/datasheet-523-r-ras-c-19-antibody.htm...

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Cell Biology: primary antibodies, proteins, peptides, kits | Abcam
... RNF7 proteins and peptides (1) · RPS3 antibodies (2) · RRAGC antibodies (1) · RRAS antibodies (3) · SEC14 like protein 2 antibodies (2) ...
http://www.abcam.com/index.html?cl=246&pageconfig=productmap...

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The inaugural meeting Stem Cells 2006: Mexican Riviera Cancun ...
hypoxia, including Ak4, Akt3, Col X, Fmod, Ier3, IGFbp4, MafF, Mxi1, Rcor2, Rras , Sox6,. Tnni2, Wnt5a, and Zfp313. Page 141. Yunfei Zhou. Abstract P89 ...
http://www.abcam.com/ps/pdf/stemcells/stemcells06_programme....

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