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CLIP1
| Symbol: | CLIP1 | | Name(s): | CAP-GLY domain containing linker protein 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CLIP, CLIP-170, CLIP170, CYLN1, MGC131604, RSN | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18237546 |
The results suggest that promotion of lamellipodia formation and invasion by HGF or serum requires PI3K-dependent release of IQGAP1 and kinesin from Rac1-CLIP-170 complex. |
| 17828277 |
Data use the complex formed between the CAP-Gly domain of p150(glued) and the C-terminal zinc knuckle of CLIP170 as a model system to explore the structure-function relationship of CAP-Gly-mediated protein interactions. |
| 17889670 |
Crystal structures of the tubulin binding domains of XMAP215 (yeast Stu2p and Drosophila Msps), EB1 (yeast Bim1p and human EB1), and CLIP-170 (human), which reveal diverse tubulin binding interfaces, are reported. |
| 12833147 |
neogenin and restin have roles in proproliferation/survival action on ovarian cancer cells |
| 11966772 |
The cytoplasmic linker protein CLIP-170 is a human autoantigen |
| 12110184 |
Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170. |
| 17563362 |
A structural basis for tubulin recognition by CLIP-170 and its autoinhibition is provided. |
| 12433698 |
expressed at high levels in monocyte-derived dendritic cells and IL-4 + CD40L-activated B cells and is involved in the trafficking of macropinosomes to the cytoskeleton, a crucial step in antigen presentation |
| 16772339 |
The function of CLIP-170 in membrane trafficking is not associated with plus-end localization. |
| 11940666 |
LIS1, CLIP-170's key to the dynein/dynactin pathway | →View more information from publications. |
Recent Publications on CLIP1: |  |
Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM.
Atypical invariant chain (Ii) CLIP fragments (CLIP2) have been found in... | 22nd October, 2008
| Centre for Immune Regulation and Institute of Immunology, University of
| J Immunol. 2008 Oct 15;181(8):5451-61.
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[Influence of Smad4-independent pathway of transforming growth factor beta1 on the biological activity of pancreatic cancer cells]
OBJECTIVE: To study effects of the expression of transforming growth... | 16th May, 2007
| Department of Pathology, Changhai Hospital, Second Military Medical
| Zhonghua Bing Li Xue Za Zhi. 2005 Jul;34(7):413-6.
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[Expression of p16INK4a, p15INK4b, p21WAF1/Clip1 cell cycle inhibitors on blastic cells in patients with acute myeloblastic leukemia (AML) and acute lymphoblastic leukemia (ALL) ]
Cyclin-dependent kinases (cdk) play the important role in neoplastic... | 21st March, 2003
| Katedra i Klinika Hematologii i Chorob Rozrostowych AM we Wroclawiu.
| Pol Arch Med Wewn. 2002 Sep;108(3):849-53.
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Human DNA-Topoisomerases - Diagnostic and Therapeutic Implications for Cancer.
Topoisomerases constitute a family of highly conserved essential enzymes,... | 7th July, 2001
| Institut fur Pathologie, Otto-von-Guericke-Universitat, Magdeburg.
| Onkologie. 2000 Oct;23(5):424-430.
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CLIP1 results (if any) from reagent suppliers | 
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CLIP-170 (N-18) Antibody sc-12799
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, CLIP1, 6249, 12q24.31, NM_002956, ...
http://www.scbt.com/datasheet-12799-clip-170-n-18-antibody.h...
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Recent Search Terms used to find this page: CAP-GLY domain containing linker protein | CAP-Gly domain-containing linker protein 4 | zinc knuckle-domain containing protein | CLIP1 restin | CAP-GLY domain containing linker protein family | How protein linkers to link | CAPS1 dynactin | function of zinc knuckle domain-containing protein | CLIP1 CAP-GLY domain containing linker protein 1 | .
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