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BDNF


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Gene DB Home
Symbol:BDNF
Name(s):brain-derived neurotrophic factor
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC34632
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17579366 brain derived neurotrophic factor Met allele(s) moderated the effect of early adversity on depressive symptoms (two-way interaction)
18203754 Observational study of gene-disease association. (HuGE Navigator)
18205169 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
18242852 Observational study of gene-disease association. (HuGE Navigator)
18242855 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18263664 Observational study of gene-disease association. (HuGE Navigator)
18286632 Observational study of gene-disease association. (HuGE Navigator)
18294085 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18325670 Observational study of gene-disease association. (HuGE Navigator)
18347599 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDbrain-derived neurotrophic factornitric oxide synthase 3--Pubmed
HPRDbrain-derived neurotrophic factornitric oxide synthase 3--Pubmed
HPRDbrain-derived neurotrophic factorneural cell adhesion molecule 1 isoform 1--Pubmed
HPRDbrain-derived neurotrophic factorneural cell adhesion molecule 1 isoform 1--Pubmed
HPRDbrain-derived neurotrophic factorneurotrophin 3 isoform 2 preproprotein--Pubmed
HPRDbrain-derived neurotrophic factorneurotrophin 3 isoform 2 preproprotein--Pubmed
HPRDbrain-derived neurotrophic factorneurotrophin 5 preproprotein--Pubmed
HPRDbrain-derived neurotrophic factorneurotrophin 5 preproprotein--Pubmed
HPRDbrain-derived neurotrophic factorneurotrophic tyrosine kinase, receptor, type 2 isoform a precursor--Pubmed
HPRDbrain-derived neurotrophic factorneurotrophic tyrosine kinase, receptor, type 2 isoform a precursor--Pubmed

Recent Publications on BDNF:

Pubmed Logo
Androgen Regulates Brain-Derived Neurotrophic Factor in Spinal Motoneurons and Their Target Musculature.
Trophic factors maintain motoneuron morphology and function in adulthood....
3rd November, 2009
Department of Psychological and Brain Sciences and Program in Endocrinology. 2009 Oct 30.
DOI Direct Link
Pharmacogenetics studies in STAR*D: strengths, limitations, and results.
Several lines of evidence support an important genetic contribution to the...
3rd November, 2009
Genetic Basis of Mood and Anxiety Disorders Unit, National Institute of Psychiatr Serv. 2009 Nov;60(11):1446-57.
DOI Direct Link
Site-Specific Antidepressant Effects of Repeated Subconvulsive Electrical Stimulation: Potential Role of Brain-Derived Neurotrophic Factor.
BACKGROUND: Electroconvulsive therapy (ECT) is a very effective treatment...
3rd November, 2009
Department of Neurobiology, Weizmann Institute of Science, Rehovot, Biol Psychiatry. 2009 Oct 30.
DOI Direct Link
Phylogenesis of Brain Derived Neurotrophic Factor (BDNF) in Vertebrates.
Brain-Derived Neurotrophic Factor (BDNF) belongs to neurotrophin family, a...
3rd November, 2009
Dipartimento di Biotecnologie e Scienze Molecolari, Universita degli Studi Gene. 2009 Oct 28.
DOI Direct Link
THE LAMELLAR CELLS IN HUMAN MEISSNER CORPUSCLES EXPRESS TrkB.
Cutaneous Meissner corpuscles depend for development and survival...
3rd November, 2009
Departamentos de Morfologia y Biologia Celular, Universidad de Oviedo, Neurosci Lett. 2009 Oct 28.
DOI Direct Link

View more research publications.

Press Releases on BDNF:

BioPortfolio Logo
Reportlinker Adds World Neurodegenerative Diseases Market 2009-2024 3rd November, 2009 Reportlinker
-- Rilutek.

In our pipeline analyses we include emerging therapeutics such as stem cells, gene therapy and monoclonal antibodies, among other prominent developments.

Sigma-Aldrich Announces SAGE(TM) Priority Partners Program; Seeks Researchers to Evaluate New Knockout Rat Models 20th October, 2009 Sigma-Aldrich
4. BDNF - Brain derived neurotrophic factor - The BDNF protein is a nerve growth factor found in the brain that acts by supporting existing neurons and encouraging the growth of new
Raptor Pharmaceuticals to Collaborate with Centre Hospitalier Universitaire d'Angers for Phase II Clinical Trial in Huntington's Disease 10th November, 2008

NOVATO, California, November 10 /PRNewswire/ -- Raptor Pharmaceuticals Corp. ("Raptor" or the "Company") (OTC Bulletin Board: RPTP), today announced that the Company has entered

Raptor Pharmaceuticals to Collaborate with Centre Hospitalier Universitaire d?Angers for Phase II Clinical Trial in Huntington?s Disease 10th November, 2008 Raptor Pharmaceuticals Corp.

NOVATO, Calif., Nov. 10 /PRNewswire-FirstCall/ -- Raptor Pharmaceuticals Corp. ("Raptor" or the "Company") (OTC Bulletin Board: RPTP), today announced that the Company has

BioNews Results for BDNF

: RSS Logo
BioPortfolio Logo
Science: a gene that drives you to distraction
Times Online:  Nov 13 2009 11:17PM Matching: bdnf
A rat model for studying neural stem cell transplantation
Nature:  Nov 11 2009 12:58PM Matching: bdnf
Bad Genetics Make Bad Drivers
cars.com:  Nov 5 2009 12:40AM Matching: bdnf
Bad driving could be in the genes
Canadian Underwriter:  Nov 5 2009 1:32AM Matching: bdnf
Bad driving might be linked to genes, study finds
Houston Chronicle:  Nov 3 2009 7:07PM Matching: bdnf
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Effect of Salmeterol on Brain-Derived Neurotrophic Factor (BDNF) Concentrations in Asthma

Patents:

Patents logo
US Patent No.Title
7575589 Light-emitting device and method for providing phototherapy to the brain
7585671 Hedgehog interacting proteins and uses related thereto
7585673 .gamma.-heregulin
7585880 Phenylpropanoic acid derivatives
7585892 Compound for promoting the growth of neural cells

View more patents.

BDNF results (if any) from reagent suppliers

Google CSE Logo
BDNF antibody (ab9793) | Abcam
Western Blot:To detect BDNF by Western Blot analysis this antibody can be used at a ... Contact Abcam with a Technical Enquiry about BDNF antibody ...
http://www.abcam.com/BDNF-antibody-ab9793.html...

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BDNF Antibody / BDNF Antibodies
BDNF Antibody / BDNF Antibodies. ... BDNF specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-bdnf.html...

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Antibody Assistant - Anti-Human BDNF pAb
BDNF, a 27kDa homodimer originally derived from human brain and which shares high sequence homology with NGF, NT-3 and NT-4/5, influences many neuron types
...
http://www.promega.com/techserv/tools/abasst/AntibodyPages/A...

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BDNF antibody (ab46176) | Abcam
The antibody is specific to recombinant BDNF protein and when used in rat brains extracts .... Contact Abcam with a Technical Enquiry about BDNF antibody ...
http://www.abcam.com/BDNF-antibody-ab46176.html...

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BDNF Antibody Biotin - Anti-Human BDNF - Rabbit
BDNF antibody: Polyclonal rabbit antibody from ProSci Incorporated for research on growth factors,
http://www.prosci-inc.com/shop/catalog1/BDNF-Antibody-p-1901...

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BDNF antibody (ab6201) | Abcam
Brain derived neurotrophic factor (BDNF) is a member of the neurotrophin ... ab6201 BDNF antibody immunostaining in the ventral horn of the spinal cord. ...
http://www.abcam.com/BDNF-antibody-ab6201.html...

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BDNF (N-20) Antibody sc-546
Positive AMPA receptor modulation rapidly stimulates BDNF release and increases ... Cryostat sections of mouse skin showing hair follicle staining with BDNF ...
http://www.scbt.com/datasheet-546-bdnf-n-20-antibody.html...

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